1005: David Fajgenbaum | Leveraging AI to Cure Rare Diseases

Update: There is some controversy about the information presented in this episode. A counterpoint to some of the statistics and specifics on the problem of human/child trafficking is in this piece released on Dec 9, 2021 from The Atlantic.  Tim Ballard (@TimBallard) is a former Homeland Security agent who reluctantly got involved in chasing down global child trafficking. As the founder of Operation Underground Railroad, he is featured in the documentary film Operation Toussaint: Operation Underground Railroad and the Fight to End Modern Day Slavery, and is a co-author of the book adaptation as well as Slave Stealers: True Accounts of Slave Rescues -- Then and Now. What We Discuss with Tim Ballard: Slavery is the fastest-growing criminal enterprise in the world. There are more people enslaved right now than there were during the transatlantic slave trade period between the 15th and 19th centuries. Slavery generates three times the revenue of the NFL. With the money from all the trafficking in the world, you could buy every Starbucks outlet in the world. Every NBA team in the nation. Every Target store. There are 30 million slaves in the world; 10 million of them are children. 17,500 children are trafficked into the US every year. And much more... Full Show Notes and Resources Can Be Found Here: jordanharbinger.com/369 Sign up for Six-Minute Networking -- our free networking and relationship development mini course -- at jordanharbinger.com/course! Like this show? Please leave us a review here -- even one sentence helps! Consider including your Twitter handle so we can thank you personally!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

25 Juni 20201h 15min

Coffeezilla (@coffeebreak_YT) is a prolific YouTuber who exposes fake guru scam artists and alerts would-be victims to the tactics used to part them from their hard-earned money. What we discuss with Coffeezilla: How fake gurus who profess to teach you how to get rich quick aren't using these same methods to get rich -- they're using you. The classic framework used by fake gurus to entice their target demographic. How fake gurus leverage cult of personality dynamics to be both relatable and unquestionable. How fake gurus pass off once-legitimate moneymaking methods long after they've become obsolete and worthless. Why you don't have to be especially gullible to fall for what a fake guru is selling, and you don't have to be a steel-willed ice king or queen to resist their sleazy machinations. And much more... Full show notes and resources can be found here: jordanharbinger.com/368 Sign up for Six-Minute Networking -- our free networking and relationship development mini course -- at jordanharbinger.com/course! Like this show? Please leave us a review here -- even one sentence helps! Consider including your Twitter handle so we can thank you personally!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

23 Juni 20201h 22min

Your significant other has picked up some bad habits while self-quarantining during the pandemic; how can you fix your relationship without nagging? We'll figure out this -- and more -- here on Feedback Friday! And in case you didn't already know it, Jordan Harbinger (@JordanHarbinger) and Gabriel Mizrahi (@GabeMizrahi) banter and take your comments and questions for Feedback Friday right here every week! If you want us to answer your question, register your feedback, or tell your story on one of our upcoming weekly Feedback Friday episodes, drop us a line at friday@jordanharbinger.com. Now let's dive in! Full show notes and resources can be found here: https://jordanharbinger.com/367. On This Week's Feedback Friday, We Discuss: First, let's address some reactions to the advice we gave to the ex-self-help cultist/current registered sex offender featured on a recent Feedback Friday. Moving across the country would afford you better business opportunities, but leave you without the safety net of free housing you enjoy now. How can you be confident enough to take this big, scary leap and ensure you do it right? Your significant other has picked up some bad habits while self-quarantining during the pandemic; how can you fix your relationship without nagging? You seem to show appreciation more than verbalize it, but you want to be good at both. How can you improve your ability to verbalize appreciation? You're working at one of the top places in your field and it's making you second-guess your choice of career. So is it time to find a new career entirely, or just a new place to work? You work for a well-known, rapidly growing startup, and former colleagues, peers, and friends of friends are reaching out for referrals. So how do you honestly deal with the ones you're not entirely stoked about referring? Are you thinking about confidence wrong? Don Moore, author of Perfectly Confident: How to Calibrate Your Decisions Wisely joins us to find out and, if so, offer some course corrections. A shout out to Christina (and Elisa and Garrett) for letting us know how our episodes with BJ Fogg and Ramit Sethi helped them change up their habits and their money! Have any questions, comments, or stories you'd like to share with us? Drop us a line at friday@jordanharbinger.com! Connect with Jordan on Twitter at @JordanHarbinger and Instagram at @jordanharbinger. Connect... See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

19 Juni 20201h

Bill Nye (@billnye) is a lifelong champion of science who is determined to teach you something today that you didn't know yesterday -- whether it's from a television screen, the pages of a book, or next to you at a dinner party. What We Discuss with Bill Nye: Why denying proven science -- like climate change and the efficacy of vaccination -- is in nobody's best interest. On reinvention and pivoting: How Bill Nye went from Boeing engineer to television personality. Why episodes of Bill Nye The Science Guy are still being used to teach kids science two decades after they first aired. How to look at the world with radical curiosity. Why it's key to internalize our fears in order to move forward. And so much more... Full show notes and resources can be found here: https://jordanharbinger.com/366 Sign up for Six-Minute Networking -- our free networking and relationship development mini course -- at jordanharbinger.com/course! Like this show? Please leave us a review here -- even one sentence helps! Consider including your Twitter handle so we can thank you personally!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

18 Juni 202046min

Benjamin Hardy (@BenjaminPHardy) is an organizational psychologist and author of Willpower Doesn't Work: Discover the Hidden Keys to Success and Personality Isn't Permanent: Break Free from Self-Limiting Beliefs and Rewrite Your Story. What We Discuss with Benjamin Hardy: Why treating the results of a "scientific" personality test like Myers & Briggs or Enneagram as gospel is akin to trusting horoscopes to safely guide your life decisions -- inaccurate and potentially dangerous. Hear the story about how Benjamin and his wife almost didn't get married because a personality test indicated they weren't an ideal match. What looking back at the person you were 10 or 20 years ago should reveal about personality as an unfixed, malleable quality. Why categorizing yourself or accepting labels leads to a tunnel vision of mindlessness that tends to accentuate the negative qualities you believe yourself to have. You're always a work in progress -- you're never "finished." The person you'll be in 10 years may well be as different as you are from the person you were 10 years ago. So who do you want the future you to be? And much more... Full show notes and resources can be found here: https://jordanharbinger.com/365 Sign up for Six-Minute Networking — our free networking and relationship development mini course — at jordanharbinger.com/course! Like this show? Please leave us a review here -- even one sentence helps! Consider including your Twitter handle so we can thank you personally!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

16 Juni 20201h 4min

One of your fellow medical students is openly racist, misogynistic, and homophobic. Do you have a duty to report this terrible person in hopes it prevents him from ever becoming a doctor with marginalized patients whose lives may depend on him? We'll tackle this and more here on Feedback Friday! And in case you didn't already know it, Jordan Harbinger (@JordanHarbinger) and Gabriel Mizrahi (@GabeMizrahi) banter and take your comments and questions for Feedback Friday right here every week! If you want us to answer your question, register your feedback, or tell your story on one of our upcoming weekly Feedback Friday episodes, drop us a line at friday@jordanharbinger.com. Now let's dive in! Full show notes and resources can be found here: https://jordanharbinger.com/364. On This Week's Feedback Friday, We Discuss: If someone could only see your actions and not hear your words, what would they say are your priorities? One of your fellow medical students is openly racist, misogynistic, and homophobic. Do you have a duty to report this terrible person in hopes it prevents them from ever becoming a doctor? You're skeptical of mainstream viewpoints and want to explore every angle of an issue, but you find yourself getting sucked into conspiracy theory-level stuff. How can you maintain a healthy balance that errs toward accuracy, not nonsense? You're in school to be an airline pilot (your lifelong dream), but COVID-19 has decimated the industry and made your chance of being hired in the US uncertain. What options might you explore? You read so many books and consume such a vast amount of information that it becomes difficult to remember the important bits. How can you retain this data without becoming overwhelmed? VPN! Huh! What is it good for? Absolutely lots, as ExpressVPN VP Harold Li explains here. Life Pro Tip: When you’re dealing with someone who is notoriously bad at responding to email and you need to ask them a yes/no question, frame your question so that their lack of reply is a response.  Recommendation of the Week: Mr. Toilet: The World’s #2 Man Have any questions, comments, or stories you'd like to share with us? Drop us a line at friday@jordanharbinger.com! Connect with Jordan on Twitter at @JordanHarbinger and Instagram at See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

12 Juni 202050min

Mick West (@mickwest) is a co-founder and former technical director of Neversoft Entertainment, coder, pilot, Metabunk and  Contrail Science founder, and author of Escaping the Rabbit Hole: How to Debunk Conspiracy Theories Using Facts, Logic, and Respect. What We Discuss with Mick West: Why people believe -- and want to believe -- conspiracy theories. The types of bias and bad thinking that allow conspiracy theories to take root and thrive. Who really benefits from propagating conspiracy theories and what they have to gain. Ways in which we can help people discover bad thinking patterns in themselves and others. How to help our friends and family escape the conspiracy theory rabbit hole. And much more... Full show notes and resources can be found here: https://jordanharbinger.com/363 Sign up for Six-Minute Networking -- our free networking and relationship development mini course -- at jordanharbinger.com/course! Like this show? Please leave us a review here -- even one sentence helps! Consider including your Twitter handle so we can thank you personally!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

11 Juni 20201h 36min

Mark Cuban (@mcuban) is a Shark Tank investor in over 200 companies, owner of the Dallas Mavericks, and author of How to Win at the Sport of Business: If I Can Do It, You Can Do It. What We Discuss with Mark Cuban: The advice Mark is giving his CEOs and founders during these angry, uncertain, and unprecedented times. What Mark sees as the future of the knowledge and technology economies here in the United States. What jobs will exist in the not-so-distant future? How America can beat China, and the areas we need to invest in to do so. How Mark stays on top of trends and separates fact from fiction when it comes to his investments -- and how to reach Mark and get his attention for your own business idea. And much more... Full show notes and resources can be found here: https://jordanharbinger.com/362 Sign up for Six-Minute Networking -- our free networking and relationship development mini course -- at jordanharbinger.com/course! Like this show? Please leave us a review here -- even one sentence helps! Consider including your Twitter handle so we can thank you personally!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

9 Juni 202050min