Harnessing the Immune System in Relapsed AML: Dr. Reagan, Rhode Island Hospital

Harnessing the Immune System in Relapsed AML: Dr. Reagan, Rhode Island Hospital

The use of the immune system to treat patients with AML is being heavily pursued as a strategy to more effectively fight AML and give patients with relapsed or refractory disease a better chance at achieving remission or a cure. Immunotherapy in the form of allogeneic stem cell transplant has been a foundation of curative therapy in AML since the 1970s. While the effectiveness and tolerability of stem cell transplant has improved over the years, significant limitations still exist, warranting the development of new and improved immunotherapy options. Join us live September 30th at 12 PM Central to learn from Dr. John Reagan, an AML expert from Rhode Island Hospital, about what steps you can take if you have relapsed or refractory AML. He will be discussing what immunotherapy is, it’s current use in AML and his open clinical trial looking at whether the FDA approved drug Gemtuzumab, followed by an infusion of blood cells called leukocytes from a donor, can stimulate the immune system to potentially fight AML.

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HealthTree Podcast for AML: Gabriela Hobbs, MD, Massachusetts General Hospital

HealthTree Podcast for AML: Gabriela Hobbs, MD, Massachusetts General Hospital

Allogeneic stem cell transplantation is the only curative option for patients battling acute myeloid leukemia. However, a significant number of patients will relapse after transplant. Innovative resea...

5 Okt 20221h 2min

HealthTree Podcast for AML: Eytan Stein, MD, Memorial Sloan Kettering

HealthTree Podcast for AML: Eytan Stein, MD, Memorial Sloan Kettering

The IDH mutation can be found in approximately 20% of adult AML cases. Isocitrate dehydrogenase isoform 1 and 2 or IDH1 and IDH2 mutations are typically found in older AML patients and have an interme...

24 Aug 202258min

Digging Deeper Into the TP53 Mutation in AML with Rory Shallis, MD, Yale

Digging Deeper Into the TP53 Mutation in AML with Rory Shallis, MD, Yale

The TP53 mutation in AML is considered to be a high risk mutation and occurs in approximately 5-10% of patients. This genetic mutation has been difficult to treat, often being chemoresistant with a po...

14 Juli 20221h 1min

HealthTree Podcast for AML: Dr. Jane Liesveld, University of Rochester

HealthTree Podcast for AML: Dr. Jane Liesveld, University of Rochester

The FLT3 gene mutation is the most common mutation seen in acute myeloid leukemia patients. It occurs in up to 37% of adult patients with AML. FLT3 mutations have been harder to treat with poor outcom...

29 Juni 20221h

HealthTree Podcast for AML: Dr. Kendra Sweet, Moffitt Cancer Center

HealthTree Podcast for AML: Dr. Kendra Sweet, Moffitt Cancer Center

Immunotherapy continues to be an expanding and evolving area of research for AML with many drugs in development. One drug currently being studied is IMGN632, an antibody drug conjugate, that targets C...

9 Juni 202258min

HealthTree Podcast for AML: Dr. Joseph Jurcic, Columbia University

HealthTree Podcast for AML: Dr. Joseph Jurcic, Columbia University

Immunotherapy is one of the most promising areas of cancer research. Drugs like checkpoint inhibitors, monoclonal and bispecific anitbodies, antibody drug conjugates and CAR-T cell therapy are all ext...

26 Maj 20221h 1min

HealthTree Radio for AML:  Margaret Kasner, MD, Thomas Jefferson University

HealthTree Radio for AML: Margaret Kasner, MD, Thomas Jefferson University

About 30% of acute myeloid leukemia patients have developed a mutation in the FLT3 gene. Up until recently, this specific mutation usually resulted in poor treatment outcomes. Today, we have several d...

7 Feb 202256min

HealthTree Radio for AML: Eytan Stein, MD, Memorial Sloan Kettering

HealthTree Radio for AML: Eytan Stein, MD, Memorial Sloan Kettering

There is a tremendous amount of progress being made in AML. It was remarkable to see the significant work being done in the field of AML at the recent American Society of Hematology (ASH) conference i...

2 Feb 20221h 5min

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