Will Taking GH Before Going To Sleep Suppress Your Natural Production Of GH?
More Plates More Dates13 Feb 2020

Will Taking GH Before Going To Sleep Suppress Your Natural Production Of GH?

At supraphysiological dosages, taking GH before going to sleep makes sense because there is a negative feedback loop on the growth hormone (GH)/insulin-like growth factor I (IGF-1) axis. In this study, IGF-1 was constantly infused, and the effect on endogenous GH secretion was assessed [R]. Overall, GH concentrations were suppressed during the rhIGF-I infusion by 85±3%, mainly by attenuating spontaneous GH pulse amplitude (77±4% suppression). The apparent GH pulse frequency was attenuated from 7.8±0.9 to 4.7±0.6 pulses/24h (P= 0.006). IGF-1 is the primary feedback, and the mechanism is similar to what you see with the HPTA axis. When there is enough Testosterone and Estrogen, your body has this mechanism in place to prevent you from making more. The same thing happens with exogenous GH use. When you administer exogenous GH, IGF-1 elevates. When your body recognizes that IGF-1 is elevated, it starts to suppress GH pulse amplitude in a dose dependent manner. If you are using supraphysiological amounts of GH for bodybuilding purposes, you can assume that your natural secretion is greatly inhibited during sleep as this negative feedback loop will prevent your body from secreting GH in your sleep like it normally would. When endogenous GH production is suppressed, administering exogenous GH at times that lipolysis or muscle growth can be optimized is the most logical approach to injection timing. https://youtu.be/8j9MGfQPeXg If fat loss is the goal, then taking GH in a fasted state prior to fasted cardio would be ideal. There is a ceiling on how much GH is needed to maximize lipolysis, so if your dosage exceeds 2 IU per day, then I would advise splitting up that dose into two (or more if needed) different periods of the day with as much time between them as possible. If muscle growth is the goal, GH should still be administered in a pulsatile fashion to mimic endogenous secretions. Topped out stimulation of autocrine IGF-1 in skeletal muscle can be achieved with fairly low dosages of exogenous GH, and administering a higher dose above and beyond that may just be a waste. This is why it would be wise to split up your daily GH dose into multiple administrations if you are using supraphysiological dosages. Learn more about your ad choices. Visit megaphone.fm/adchoices

Avsnitt(1360)

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Crippling ‘Ballerina Feet’ Claw Syndrome From Limb Lengthening Surgery (6’0” → 6’6”)

📌 The 6’0” → 6’6” Limb Lengthening Surgery That Went Viral. From My Full 3+ Hour Conversation With Brian the Sasquatch Going Live Next Week. ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Rigorous Bloodwork Analysis: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— Instagram: https://www.instagram.com/moreplatesmoredates/ Twitter: https://x.com/Derek_Fitness Snapchat: https://www.snapchat.com/add/derek-fit TikTok: https://www.tiktok.com/@moreplates Facebook: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

6 Feb 20255min

Why Steroid Abusers Age Faster

Why Steroid Abusers Age Faster

📌 From my conversation with ​ @WillTennyson  about gear, TRT, and the fitness industry, coming Thursday ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Rigorous Bloodwork Analysis: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— Instagram: https://www.instagram.com/moreplatesmoredates/ Twitter: https://x.com/Derek_Fitness Snapchat: https://www.snapchat.com/add/derek-fit TikTok: https://www.tiktok.com/@moreplates Facebook: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

5 Feb 20253min

Being On TRT vs. Being On "TRT"!

Being On TRT vs. Being On "TRT"!

📌 From my conversation with ​⁠@WillTennyson about gear, TRT, and the fitness industry, coming soon ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Rigorous Bloodwork Analysis: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— Instagram: https://www.instagram.com/moreplatesmoredates/ Twitter: https://x.com/Derek_Fitness Snapchat: https://www.snapchat.com/add/derek-fit TikTok: https://www.tiktok.com/@moreplates Facebook: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

27 Jan 20254min

What % Of People On Steroids Achieved Their Natural Limit First?

What % Of People On Steroids Achieved Their Natural Limit First?

📌 From my conversation with Will Tennyson about gear, TRT, and the fitness industry, coming soon ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Rigorous Bloodwork Analysis: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— Instagram: https://www.instagram.com/moreplatesmoredates/ Twitter: https://x.com/Derek_Fitness Snapchat: https://www.snapchat.com/add/derek-fit TikTok: https://www.tiktok.com/@moreplates Facebook: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

19 Jan 20252min

Steroids Aren’t Safe, But TRT Is - True Or False?

Steroids Aren’t Safe, But TRT Is - True Or False?

📌 Check out the full podcast here: https://youtu.be/9AmUnTGo2_U ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Rigorous Bloodwork Analysis: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— Instagram: https://www.instagram.com/moreplatesmoredates/ Twitter: https://x.com/Derek_Fitness Snapchat: https://www.snapchat.com/add/derek-fit TikTok: https://www.tiktok.com/@moreplates Facebook: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

13 Jan 20255min

The Truth About Aging Clocks And Death

The Truth About Aging Clocks And Death

📌 Check out the full podcast here: https://youtu.be/_PG6sLMuWS8 ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Rigorous Bloodwork Analysis: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— Instagram: https://www.instagram.com/moreplatesmoredates/ Twitter: https://x.com/Derek_Fitness Snapchat: https://www.snapchat.com/add/derek-fit TikTok: https://www.tiktok.com/@moreplates Facebook: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

3 Jan 202522min

$25,000 Follistatin Gene Therapy - Before & After Results Analysis With Peter Attia

$25,000 Follistatin Gene Therapy - Before & After Results Analysis With Peter Attia

📌 The Full Podcast On Peter Attia's Channel: https://youtu.be/-wkQA_oxOwA ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Rigorous Bloodwork Analysis: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— Instagram: https://www.instagram.com/moreplatesmoredates/ Twitter: https://x.com/Derek_Fitness Snapchat: https://www.snapchat.com/add/derek-fit TikTok: https://www.tiktok.com/@moreplates Facebook: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

2 Jan 202518min

Bryan Johnson's $25,000 Follistatin Gene Therapy - Dissecting The Results

Bryan Johnson's $25,000 Follistatin Gene Therapy - Dissecting The Results

📌 Check out the full podcast here: https://youtu.be/_PG6sLMuWS8 ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Rigorous Bloodwork Analysis: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— Instagram: https://www.instagram.com/moreplatesmoredates/ Twitter: https://x.com/Derek_Fitness Snapchat: https://www.snapchat.com/add/derek-fit TikTok: https://www.tiktok.com/@moreplates Facebook: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

1 Jan 202521min

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