Will Taking GH Before Going To Sleep Suppress Your Natural Production Of GH?
More Plates More Dates13 Feb 2020

Will Taking GH Before Going To Sleep Suppress Your Natural Production Of GH?

At supraphysiological dosages, taking GH before going to sleep makes sense because there is a negative feedback loop on the growth hormone (GH)/insulin-like growth factor I (IGF-1) axis. In this study, IGF-1 was constantly infused, and the effect on endogenous GH secretion was assessed [R]. Overall, GH concentrations were suppressed during the rhIGF-I infusion by 85±3%, mainly by attenuating spontaneous GH pulse amplitude (77±4% suppression). The apparent GH pulse frequency was attenuated from 7.8±0.9 to 4.7±0.6 pulses/24h (P= 0.006). IGF-1 is the primary feedback, and the mechanism is similar to what you see with the HPTA axis. When there is enough Testosterone and Estrogen, your body has this mechanism in place to prevent you from making more. The same thing happens with exogenous GH use. When you administer exogenous GH, IGF-1 elevates. When your body recognizes that IGF-1 is elevated, it starts to suppress GH pulse amplitude in a dose dependent manner. If you are using supraphysiological amounts of GH for bodybuilding purposes, you can assume that your natural secretion is greatly inhibited during sleep as this negative feedback loop will prevent your body from secreting GH in your sleep like it normally would. When endogenous GH production is suppressed, administering exogenous GH at times that lipolysis or muscle growth can be optimized is the most logical approach to injection timing. https://youtu.be/8j9MGfQPeXg If fat loss is the goal, then taking GH in a fasted state prior to fasted cardio would be ideal. There is a ceiling on how much GH is needed to maximize lipolysis, so if your dosage exceeds 2 IU per day, then I would advise splitting up that dose into two (or more if needed) different periods of the day with as much time between them as possible. If muscle growth is the goal, GH should still be administered in a pulsatile fashion to mimic endogenous secretions. Topped out stimulation of autocrine IGF-1 in skeletal muscle can be achieved with fairly low dosages of exogenous GH, and administering a higher dose above and beyond that may just be a waste. This is why it would be wise to split up your daily GH dose into multiple administrations if you are using supraphysiological dosages. Learn more about your ad choices. Visit megaphone.fm/adchoices

Avsnitt(1360)

Craig Jones' Submissions Tier List - S Tier vs. Completely Useless

Craig Jones' Submissions Tier List - S Tier vs. Completely Useless

📌 Check out the full podcast here: https://youtu.be/6uy75kr_O5k ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Blood Work: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— INSTAGRAM: https://www.instagram.com/moreplatesmoredates/ TWITTER: https://twitter.com/Derek_Fitness SNAPCHAT: https://www.snapchat.com/add/derek-fit TIKTOK: https://www.tiktok.com/@moreplates FACEBOOK: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

25 Sep 20244min

+10 Pounds In 1 Week!? How Much Can Creatine Actually Increase Muscle Size And Strength?

+10 Pounds In 1 Week!? How Much Can Creatine Actually Increase Muscle Size And Strength?

📌 Third-Party Tested Micronized Creatine Monohydrate: https://gorillamind.com/products/creatine?variant=42386041929773&selling_plan=1077706797 | code "MPMD" for 10% off ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Blood Work: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— INSTAGRAM: https://www.instagram.com/moreplatesmoredates/ TWITTER: https://twitter.com/Derek_Fitness SNAPCHAT: https://www.snapchat.com/add/derek-fit TIKTOK: https://www.tiktok.com/@moreplates FACEBOOK: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

24 Sep 20244min

Homocysteine, The Vasodilation Brick Wall, And The Optimal Betaine/Trimethylglycine Dosage

Homocysteine, The Vasodilation Brick Wall, And The Optimal Betaine/Trimethylglycine Dosage

📌 Gorilla Mode and Nitric pre-workout integrate a 4 gram Betaine/TMG dosage based on this: https://gorillamind.com/collections/pre-workouts | code "MPMD" for 10% off ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Blood Work: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— INSTAGRAM: https://www.instagram.com/moreplatesmoredates/ TWITTER: https://twitter.com/Derek_Fitness SNAPCHAT: https://www.snapchat.com/add/derek-fit TIKTOK: https://www.tiktok.com/@moreplates FACEBOOK: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

16 Sep 20247min

Gorilla Mode 2.0 Pre-Workout | Comprehensive Product Dissection

Gorilla Mode 2.0 Pre-Workout | Comprehensive Product Dissection

🦍 Gorilla Mode 2.0 Pre-Workout Is Now Live! | https://gorillamind.com/products/gorilla-mode | code "MPMD" for 10% off ———————————— 📌 Table Of Contents: • [0:00] Intro • [1:58] What Changed and Why? • [6:32] Summary Of Changes • [13:54] The Formula • [15:26] Dosage Changes • [16:38] Ingredient Additions • [17:57] Ingredient Removals • [26:44] Flavors & Mixability • [28:25] Formula Breakdown ○ [28:26] Essential Vitamins ∙ [30:08] Niacin (as Niacinamide) – 32 mg ∙ [30:34] P5P (Vitamin B6) (as Pyridoxal 5’-Phosphate) – 20 mg ∙ [31:56] Vitamin B12 (as Methylcobalamin) – 250 mcg ○ [33:05] Minerals & Electrolytes – 1430 mg ∙ [34:09] Impact Of Hydration ∙ [36:58] Pump, Performance, And Muscular Creatine Uptake ○ [41:26] Pure L-Citrulline (not Citrulline Malate) – 10,000 mg ∙ [45:49] Why Nitric Oxide Is Important ∙ [48:00] Muscular Endurance, RPE, And Relief Of Muscle Soreness ∙ [50:55] Explosive Power And Grip Strength ∙ [51:34] Vasodilation, Power Output, And Time To Exhaustion ∙ [52:13] Citrulline Vs. Arginine ∙ [53:12] Cardiometabolic Health ∙ [54:21] The Problem With Citrulline Malate In The Supplement Industry ○ [1:00:48] Malic Acid – 3000 mg ○ [1:05:30] Creatine Monohydrate – 5000 mg ∙ [1:05:57] How Much Can Creatine Increase Strength? ∙ [1:06:44] 10+ Pound Gain In A Week After Starting Creatine!? How Much Does Creatine Increase Muscle Size? ∙ [1:08:54] Carbohydrate Mediated Muscle Glycogen Supercompensation ∙ [1:09:39] Does Creatine Increase Your Natural Limit? The Effect On Satellite Cells & Myonuclei ∙ [1:10:58] Myostatin Levels ∙ [1:14:47] Cognitive Function ∙ [1:15:32] Do You Need To Supplement Creatine? Or Can You Get It Through Diet? ∙ [1:17:05] Methylation And Health Status ∙ [1:21:19] Why Include Creatine In A Pre-Workout If Its Effects Accumulate? ∙ [1:24:56] Does Timing Of When You Take Creatine Matter? ∙ [1:26:05] Do You Need To Cycle Off? ∙ [1:27:08] Does Creatine Cause Kidney Damage? ∙ [1:27:55] The Optimal Dosage ○ [1:30:20] L-Tyrosine – 5000 mg ∙ [1:31:03] The Pathway For Catecholamine And Trace Amine Synthesis ∙ [1:31:46] Reaction Time And Vigilance ∙ [1:31:59] Memory And Military Tracking Performance ∙ [1:32:54] Dextroamphetamine Vs. L-Tyrosine ∙ [1:34:52] Cognitive Flexibility ∙ [1:35:18] Endurance In Heat ○ [1:36:56] Betaine Anhydrous (Trimethylglycine) – 4000 mg ∙ [1:38:53] Muscular Strength, Power, And Size ∙ [1:43:23] Homocysteine And The Vasodilation Brick Wall ∙ [1:47:33] The Optimal Dosage (More Isn’t Always Better) ○ [1:51:20] Hydroprime® Glycerol Powder (65%) – 4000 mg ∙ [1:52:35] IV Infusion Of Fluids Vs. Oral Glycerol For Enhancing Endurance ∙ [1:53:52] Aerobic And Anaerobic Performance ∙ [1:54:30] The Synergistic Effect Of Glycerol + Creatine ∙ [1:58:35] Dosage ∙ [2:01:14] Why We Switched From Glycerpump® To Hydroprime® ○ [2:02:54] Alpha-GPC 50% (L-alpha-glycerylphosphorylcholine) – 800 mg ∙ [2:03:59] Memory, Focus And Overall Cognitive Function ∙ [2:06:25] HGH Production ∙ [2:07:19] Force Production And Power Output ∙ [2:11:41] Motivation Levels ∙ [2:12:43] Alpha-GPC Vs. Citicoline (CDP-Choline) ∙ [2:17:37] How Much Choline Do You Need Per Day? ∙ [2:19:05] How Choline Affects Methylation And Health Status ○ [2:21:15] Caffeine Anhydrous – 400 mg ∙ [2:22:23] Strength And Power ∙ [2:27:09] Workload When Well-Slept Vs. Sleep Deprived ∙ [2:27:58] Energy Expenditure (Calories Burned) Per Day ∙ [2:28:47] Alertness, Wakefulness And Readiness ∙ [2:29:09] Attention And Concentration ∙ [2:29:45] Working Memory ∙ [2:30:22] Reaction Time ∙ [2:31:44] Mental Fatigue ∙ [2:31:55] The Minimum Effective Dose ∙ [2:33:10] The Dosage Necessary For Enhanced Mental Or Physical Performance ∙ [2:36:22] Should You Wait 90 Minutes After Waking Up To Take Caffeine? ○ [2:44:17] Huperzine A – 200 mcg ∙ [2:44:31] Cholinergic Activity ∙ [2:46:35] Dopaminergic Activity ∙ [2:47:36] Participants Infused With IV Cocaine • [2:49:57] Ingredients I Didn’t Include In The Formula And Why • [3:55:12] Conclusion ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

13 Sep 20243h 57min

What Happened To Dave Bautista?

What Happened To Dave Bautista?

📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Blood Work: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— INSTAGRAM: https://www.instagram.com/moreplatesmoredates/ TWITTER: https://twitter.com/Derek_Fitness SNAPCHAT: https://www.snapchat.com/add/derek-fit TIKTOK: https://www.tiktok.com/@moreplates FACEBOOK: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

10 Sep 202418min

When You Pick The WRONG Training Partner

When You Pick The WRONG Training Partner

📌 Check out the full podcast here: https://youtu.be/6uy75kr_O5k ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Blood Work: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— INSTAGRAM: https://www.instagram.com/moreplatesmoredates/ TWITTER: https://twitter.com/Derek_Fitness SNAPCHAT: https://www.snapchat.com/add/derek-fit TIKTOK: https://www.tiktok.com/@moreplates FACEBOOK: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

10 Sep 20245min

The Diet Stan Put Gordon Ryan On To Get Jacked

The Diet Stan Put Gordon Ryan On To Get Jacked

📌 Check out the full podcast here: https://youtu.be/IfRbc1E9boM ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Blood Work: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— INSTAGRAM: https://www.instagram.com/moreplatesmoredates/ TWITTER: https://twitter.com/Derek_Fitness SNAPCHAT: https://www.snapchat.com/add/derek-fit TIKTOK: https://www.tiktok.com/@moreplates FACEBOOK: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

10 Sep 20242min

The World Champion Combination Of Autism And Steroids In Jiu Jitsu

The World Champion Combination Of Autism And Steroids In Jiu Jitsu

📌 Check out the full podcast here: https://youtu.be/6uy75kr_O5k ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Blood Work: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— INSTAGRAM: https://www.instagram.com/moreplatesmoredates/ TWITTER: https://twitter.com/Derek_Fitness SNAPCHAT: https://www.snapchat.com/add/derek-fit TIKTOK: https://www.tiktok.com/@moreplates FACEBOOK: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

19 Aug 20242min

Populärt inom Utbildning

rss-bara-en-till-om-missbruk-medberoende-2
historiepodden-se
det-skaver
nu-blir-det-historia
harrisons-dramatiska-historia
johannes-hansen-podcast
allt-du-velat-veta
alska-oss
not-fanny-anymore
rss-sjalsligt-avkladd
sektledare
polisutbildningspodden
rikatillsammans-om-privatekonomi-rikedom-i-livet
rss-om-vi-ska-vara-arliga
sa-in-i-sjalen
sektpodden
vi-gar-till-historien
i-vantan-pa-katastrofen
rss-max-tant-med-max-villman
sex-pa-riktigt-med-marika-smith