#164 – Kevin Esvelt on cults that want to kill everyone, stealth vs wildfire pandemics, and how he felt inventing gene drives

#164 – Kevin Esvelt on cults that want to kill everyone, stealth vs wildfire pandemics, and how he felt inventing gene drives

"Imagine a fast-spreading respiratory HIV. It sweeps around the world. Almost nobody has symptoms. Nobody notices until years later, when the first people who are infected begin to succumb. They might die, something else debilitating might happen to them, but by that point, just about everyone on the planet would have been infected already.

And then it would be a race. Can we come up with some way of defusing the thing? Can we come up with the equivalent of HIV antiretrovirals before it's too late?" — Kevin Esvelt

In today’s episode, host Luisa Rodriguez interviews Kevin Esvelt — a biologist at the MIT Media Lab and the inventor of CRISPR-based gene drive — about the threat posed by engineered bioweapons.

Links to learn more, summary and full transcript.

They cover:

  • Why it makes sense to focus on deliberately released pandemics
  • Case studies of people who actually wanted to kill billions of humans
  • How many people have the technical ability to produce dangerous viruses
  • The different threats of stealth and wildfire pandemics that could crash civilisation
  • The potential for AI models to increase access to dangerous pathogens
  • Why scientists try to identify new pandemic-capable pathogens, and the case against that research
  • Technological solutions, including UV lights and advanced PPE
  • Using CRISPR-based gene drive to fight diseases and reduce animal suffering
  • And plenty more.

Producer and editor: Keiran Harris
Audio Engineering Lead: Ben Cordell
Technical editing: Simon Monsour
Additional content editing: Katy Moore and Luisa Rodriguez
Transcriptions: Katy Moore

Avsnitt(318)

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#230 – Dean Ball on how AI is a huge deal — but we shouldn’t regulate it yet

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We often worry about AI models “hallucinating” or making honest mistakes. But what happens when a model knows the truth, but decides to deceive you anyway to achieve a goal of its own? This isn’t sci-...

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Rob & Luisa chat kids, the 2016 fertility crash, and how the 50s invented parenting that makes us miserable

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Global fertility rates aren’t just falling: the rate of decline is accelerating. From 2006 to 2016, fertility dropped gradually, but since 2016 the rate of decline has increased 4.5-fold. In many weal...

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#228 – Eileen Yam on how we're completely out of touch with what the public thinks about AI

#228 – Eileen Yam on how we're completely out of touch with what the public thinks about AI

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#227 – Helen Toner on the geopolitics of AGI in China and the Middle East

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