#299 Why Fasting Slows Brain Aging - Mark Mattson

#299 Why Fasting Slows Brain Aging - Mark Mattson

Welcome to the Siim Land Podcast I’m your host Siim Land and today our guest is Mark Mattson. Mark is a professor of neuroscience at John Hopkins University and is known for his early research on intermittent fasting. The National Institute of Health considers him “one of the world’s top experts on the potential cognitive and physical health benefits of intermittent fasting”. This episode is brought to you by BluBlox – my favorite light and sleep optimization company. Artificial light at night exposure at night is associated with diabetes, obesity, heart disease, cancer, and Alzheimer’s. BluBlox provides the highest quality blue-blocking glasses that filter out the specific wavelengths that have been shown to suppress melatonin in studies. Melatonin is more than the sleep hormone. It’s also vital for longevity, anti-aging and immunity. Artificial light exposure suppresses melatonin up to 99% and makes your brain think it’s daytime before bed. That’s why I love using my BluBlox blue blockers to guarantee my body is making a high amount of melatonin prior to sleep. They also have daytime lenses that you can use to reduce digital eye strain and retinal damage when working in front of a computer all day. You can get a sweet 15% discount off all the BluBlox glasses, red light bulbs, red light devices, and sleep masks if you head over to blublox.com/siimland and use the code SIIM15. That’s BLUBLOX.com/SIIMLAND and the code is SIIM15. Timestamps: 01:40 Mark Mattson Intermittent Fasting Book 06:25 What Happens to Your Body During Fasting 13:30 Fasting Benefits on the Brain 16:45 How Long Do You Need to Fast 22:50 Siim's Fasting Window Explained 25:37 How Fasting Affects Neurotransmitters 33:25 Autophagy in the Brain 41:00 Effects of Obesity and Sedentary Lifestyle 47:55 Leptin and Overeating 52:19 Are Fasting Benefits Just From Calorie Restriction 57:10 Should You Do Fasting with Migraine 01:01:40 Does Fasting Raise Cortisol Levels 01:05:35 Fasting in Mice vs Humans 01:12:45 Why Resistance Training Is Important And much more Here are the links to the podcast on all platforms Link to the Audio Podcast on iTunes and Stitcher Link to the podcast on Spotify Link to the podcast on CastBox Watch the Biohacking Bootcamp Videos on Patreon This episode is sponsored by BiOptimizers. They're giving the listeners of this podcast an exclusive offer on one of their best-selling products. It's called Magnesium Breakthrough and is the most full-spectrum magnesium supplement out there. Most supplements contain only 1 or 2 forms of magnesium... when in reality there are at least 7 that your body needs and benefits from. Magnesium is the master mineral that governs virtually all physiological processes in the body. With volume discounts combined with our custom 10% coupon code, SIIM10, you can save up to 40% off select packages of Magnesium Breakthrough! That’s an AMAZING value. And I promise that deal is ONLY available on this specific website, Click Here to Support the Show on Patreon! Show Notes Code SIIM15 for 15% OFF BluBlox My NEW Book WIN on Amazon! Join Inside Tracker for 25% Off with Code SIIMLAND Lucas Aoun's Natural Testosterone Optimization Course 10% OFF The Immunity Fix on Amazon Get Magnesium Breakthrough for a 10% Discount! Use Code SIIM for 10% Off Self Decode Use Code SIIM for a 10% Discount on the KAATSU Bands My New Book Stronger by Stress My NEW BOOK Metabolic Autophagy Metabolic Autophagy Audiobook Metabolic Autophagy Master Class Total Sleep Optimization Video Course Get the FULL GUIDE to INTERMITTENT FASTING FREE BOOK Get the Metabolic Autophagy Program Keto Adaptation Manual Book Watch the Biohacking Bootcamp Videos on Patreon Body Mind Empowerment Handbook Keto Fit Program Keto // IF Program Stay Empowered Siim

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#456 Q&A at Vitalist Bay About Health and Longevity

#456 Q&A at Vitalist Bay About Health and Longevity

Order my new book: https://www.amazon.com/dp/B0CW1B2XM1Timestamps:00:00 Intro00:18 How long do I want to live01:04 What improved my health the most02:46 Do I have a doctor04:15 Figuring out what's tru...

7 Juni 202543min

#455 The Optimal Plan to Build Muscle & Lose Fat - Menno Henselmans

#455 The Optimal Plan to Build Muscle & Lose Fat - Menno Henselmans

Order my new book: https://www.amazon.com/dp/B0CW1B2XM1Timestamps:00:00 Intro00:16 Surprising new research about muscle growth03:16 Surprising new research about diets08:16 How you need to train to bu...

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#454 25 Minutes to Make You Healthier Than 95% of People

#454 25 Minutes to Make You Healthier Than 95% of People

Order my new book: https://www.amazon.com/dp/B0CW1B2XM1Join the next conference in Tallinn, Estonia: https://www.hololifesummit.com/Timestamps:00:00 Longevity Intelligence02:30 Lifestyle risk factors0...

25 Maj 202524min

#453 Nitric Oxide: The Molecule for Better Blood Flow and Longevity

#453 Nitric Oxide: The Molecule for Better Blood Flow and Longevity

Get Bon Charge Infrared Sauna Blanket (Code SIIM): https://boncharge.com/siimlandTimestamps:00:00 Intro00:23 Why is nitric oxide important04:08 Nitric oxide, blood pressure and erectile dysfunction10:...

16 Maj 202559min

#452 Dr Eye Health Explains How to Preserve Your Eyesight with Age

#452 Dr Eye Health Explains How to Preserve Your Eyesight with Age

Order my new book: https://www.amazon.com/dp/B0CW1B2XM1Timestamps:00:00 Intro00:25 Why eye health is important02:50 Link between poor eyesight and chronic diseases05:25 Are digital screens bad for the...

9 Maj 20251h 12min

#451 Creatine Masterclass: Benefits, Myths, Dosage and Loading with Dr Darren Candow

#451 Creatine Masterclass: Benefits, Myths, Dosage and Loading with Dr Darren Candow

Get Bon Charge products (Code SIIM): https://boncharge.com/siimlandTimestamps:00:00 Intro00:25 Why is creatine the most studied supplement of all time01:45 What does creatine do to your body05:45 Why ...

2 Maj 202553min

#450 Optimize Fertility and Health in a Modern Toxic World - Kayla Barnes-Lentz

#450 Optimize Fertility and Health in a Modern Toxic World - Kayla Barnes-Lentz

Get Bon Charge Infrared Sauna Blanket (Code SIIM): https://boncharge.com/siimlandTimestamps:00:00 Intro00:35 How Kayla interviewed his date for his health04:35 Why Kayla got interested in health09:11 ...

24 Apr 20251h 7min

#449 Matt Kaeberlein Unleashed: Rapamycin, Peptides, Protein, Supplements Q&A

#449 Matt Kaeberlein Unleashed: Rapamycin, Peptides, Protein, Supplements Q&A

Timestamps:00:00 Intro00:37 Thoughts on Bryan Johnson stopping rapamycin06:59 Are more antioxidants always better09:57 Supplements versus lifestyle for longevity12:43 Life extension compounds other th...

17 Apr 20251h 11min

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