Podcast #276: Angioedema

Podcast #276: Angioedema

Author: John Winkler, M.D.

Educational Pearls

  • Angioedema is immediately life-threatening due to airway obstruction.
  • Mechanisms include allergic reaction (histamine-related) or bradykinin-related (ACE-inhibitor, C1 esterase inhibitor deficiency).
  • The bradykinin-related mechanism will not respond to the traditional meds used for anaphylaxis. Instead, use FFP to replace depleted factors.
  • If a patient displays signs of respiratory compromise, intubation is indicated. Anesthesia should be consulted as this will be a very difficult airway.

References: https://emcrit.org/pulmcrit/treatment-of-acei-induced-angioedema/

Avsnitt(1146)

Podcast # 473: Direct to Consumer Antibiotics

Podcast # 473: Direct to Consumer Antibiotics

Author: Sam Killian, MD Educational Pearls: A recent study in Pediatrics compared the rates of antibiotic prescriptions for acute respiratory infections (ARIs) between direct to consumer (DTC) teleme...

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Podcast # 472: SMART Crystalloids

Podcast # 472: SMART Crystalloids

Author: Gretchen Hinson, MD Educational Pearls: In most healthcare settings, normal saline (NS) has become ubiquitous as an intravenous fluid despite some potential drawbacks Compared to normal salin...

23 Maj 20195min

Podcast # 471: Cyclic Vomiting

Podcast # 471: Cyclic Vomiting

Author: Don Stader, MD Educational Pearls: Cyclic vomiting syndrome (CVS) is different than cannabis hyperemesis syndrome (CHS). It is important to differentiate the two. CHS is thought to be caused ...

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Podcast # 470: Zofran and Pregnancy

Podcast # 470: Zofran and Pregnancy

Author: Jared Scott, MD Educational Pearls: Ondansetron (Zofran) is one of the latest drugs that has had concerns raised about side effects, particularly in pregnancy 2018 study probed two birth defe...

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Podcast # 469: Go PO

Podcast # 469: Go PO

Author: Dave Rosenberg, MD Educational Pearls: Nothing by mouth (NPO) status routinely used before surgery to reduce the theoretical risk of aspiration However, surgery poses a large physiological st...

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Podcast # 468: Typhlitis

Podcast # 468: Typhlitis

Educational Pearls: Tiflitis refers to the presence of enterocolitis in the setting of neutropenia - also known as neutropenic enterocolitis Commonly a result of chemotherapy for hematologic malignan...

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Podcast # 467: Cauda Equina Syndrome

Podcast # 467: Cauda Equina Syndrome

Author: Erik Verzemnieks, MD Educational Pearls: Cauda equina syndrome is caused by the compression of the nerve roots that extend beyond the termination of the spinal cord Trauma, infection, hematom...

9 Maj 20192min

Podcast # 466: Subacute Sclerosing Panencephalitis

Podcast # 466: Subacute Sclerosing Panencephalitis

Author: Nicholas Hatch, MD Educational Pearls: Measles has a period of infectivity starts before the appearance of the characteristic rash, up to 4-5 days A devastating consequence of measles is Suba...

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