Podcast # 463: Buproprion Overdose

Podcast # 463: Buproprion Overdose

Author: Erik Verzemnieks, MD

Educational Pearls:

  • Buproprion is used as an antidepressant and for smoking cessation
  • Severe buproprion overdoses can cause seizures and lead to cardiac dysrhythmias
  • Benzodiazepines are treatment of choice for seizures
  • Bicarbonate and Interlipid are also possible treatment options with less evidence

References

Stall N, Godwin J, Juurlink D. Bupropion abuse and overdose. CMAJ. 2014 Sep 16;186(13):1015. doi: 10.1503/cmaj.131534. Epub 2014 Apr 28. PubMed PMID: 24778361; PubMed Central PMCID: PMC4162783.

Balit CR, Lynch CN, Isbister GK. Bupropion poisoning: a case series. Med J Aust. 2003 Jan 20;178(2):61-3. PubMed PMID: 12526723.

Bruccoleri RE, Burns MM. A Literature Review of the Use of Sodium Bicarbonate for the Treatment of QRS Widening. J Med Toxicol. 2016 Mar;12(1):121-9. doi: 10.1007/s13181-015-0483-y. Review. PubMed PMID: 26159649; PubMed Central PMCID: PMC4781799.

Avsnitt(1146)

Podcast 731: Fluid Resuscitation in Burns

Podcast 731: Fluid Resuscitation in Burns

Contributor: Chris Holmes, MD Educational Pearls: Parkland Formula: 4 mL x [Total Body Surface Area Burned (%)] x [body weight (kg)] given in 24 hours 50% given over 8 hours and 50% given over the ...

22 Nov 20214min

Podcast 730: Alternative Treatment for Gonorrhea

Podcast 730: Alternative Treatment for Gonorrhea

Educational Pearls: Recent updates to treatment guidelines increased the 250 mg ceftriaxone IM dose to 500 mg ceftriaxone IM IM dosing can be very painful, so other methods of administration can help...

16 Nov 20213min

Podcast 729: Molnupiravir for COVID

Podcast 729: Molnupiravir for COVID

Contributor: Jared Scott, MD Educational Pearls: A press release from Merck introduced Molnupiravir for treatment of mild to moderate COVID-19 The yet to be published study is a randomized control tr...

15 Nov 20215min

Podcast 728: Angiography for Out-of-Hospital Cardiac Arrest without ST Elevation

Podcast 728: Angiography for Out-of-Hospital Cardiac Arrest without ST Elevation

Contributor: Nick Tsipis, MD Educational Pearls: Meaningful survival under 10% for out of hospital cardiac arrest The most common cause of out-of-hospital cardiac arrest is due to cardiac ischemia St...

9 Nov 20215min

Podcast 727: Antibiotics for Diverticulitis

Podcast 727: Antibiotics for Diverticulitis

Contributor: Aaron Lessen, MD Educational Pearls: Classically, diverticulitis is diagnosed via CT scan and patients are discharged home on antibiotics if they are without complication The DINAMO stud...

8 Nov 20213min

Podcast 726: Ophthalmia Neonatorum

Podcast 726: Ophthalmia Neonatorum

Contributor: Peter Bakes, MD Educational Pearls: Ophthalmia Neonatorum encompasses any conjunctivitis that presents within the first 28 days of life Neonates often receive prophylactic silver nitrate...

2 Nov 20214min

Podcast 725: Hypothermia in Preterm Deliveries

Podcast 725: Hypothermia in Preterm Deliveries

Contributor: Aaron Lessen, MD Educational Pearls: Preterm deliveries in the ED can be complex and preventing hypothermia is essential to the health of the baby Recent meta-analysis examined methods f...

1 Nov 20213min

Podcast 724: Ivermectin Overdose

Podcast 724: Ivermectin Overdose

Contributor: Don Stader, MD Educational Pearls: Ivermectin is a Nobel-Prize winning antiparasitic  used to treat filariasis and onchocerciasis Ivermectin is receiving press due to a scientific study ...

26 Okt 20214min

Populärt inom Vetenskap

dumma-manniskor
svd-nyhetsartiklar
p3-dystopia
kapitalet-en-podd-om-ekonomi
allt-du-velat-veta
rss-ufo-bortom-rimligt-tvivel
det-morka-psyket
rss-vetenskapsradion
sexet
medicinvetarna
rss-vetenskapsradion-2
rss-experimentet
pojkmottagningen
dumforklarat
hacka-livet
rss-spraket
bildningspodden
rss-broccolipodden-en-podcast-som-inte-handlar-om-broccoli
rss-lara-fran-larda-en-fackbok-och-en-forfattare
intergalaktiskt