Permissive azotemia during AKI enables more rapid renal recovery and less renal fibrosis
ESICM Talk17 Maj 2023

Permissive azotemia during AKI enables more rapid renal recovery and less renal fibrosis

Preclinical models of acute kidney injury (AKI) consistently demonstrate that a uremic milieu enhances renal recovery and decreases kidney fibrosis.

Reduced renal clearance has the surprising and counterintuitive effect of being an effective treatment for AKI.

In this perspective, Dr Lakhmir S. Chawla suggests a hypothesis describing why the uremic milieu is kidney protective and proposes a clinical trial of ‘permissive azotemia’ to improve renal recovery and long-term renal outcomes in critically ill patients with severe AKI.

Hear more about the explanation of this hypothesis in the following podcast, organised by the ESICM AKI Section.

Speakers

Lakhmir S. CHAWLA. Chief Medical Officer, Silver Creek Pharmaceuticals. Recipient of the International Vicenza Award for Critical Care Nephrology.

Eric HOSTE. UZ Gent (BE). AKI Section Representative, ESICM Social Media & Digital Content Committee.

Marc ROMAIN. Hadassah Medical Center, Jerusalem (IL).

Det här avsnittet är hämtat från ett öppet RSS-flöde och publiceras inte av Podme. Det kan innehålla reklam.

Avsnitt(101)

2025 ESICM guidelines on circulatory shock and haemodynamic monitoring

2025 ESICM guidelines on circulatory shock and haemodynamic monitoring

What has changed in the 2025 ESICM guidelines on circulatory shock and haemodynamic monitoring, and what does it mean for clinical practice?In this podcast, our guest, Dr Antonio Messina, Chair of the...

23 Sep 32min

Drug Clearance in RRT: What Are the Determinants?

Drug Clearance in RRT: What Are the Determinants?

How do you optimise drug dosing in a critically ill patient undergoing continuous renal replacement therapy (CRRT)? Drug dosing during CRRT can be challenging, with multiple factors influencing drug c...

14 Sep 54min

2026 World Sepsis Day: From Awareness to Action

2026 World Sepsis Day: From Awareness to Action

This year, ESICM is proud to mark World Sepsis Day with a special podcast, "From Awareness to Action," featuring ESICM President Jan De Waele in conversation with Krista Bracke, sepsis survivor and ad...

12 Sep 43min

Heatstroke

Heatstroke

Why should every ICU clinician be prepared to recognise heat stroke?In this podcast, we explore the importance of early recognition and treatment of heat stroke, from the emergency department to the I...

26 Aug 30min

Is the curtain falling on pre-hospital whole blood?

Is the curtain falling on pre-hospital whole blood?

Whole blood has made a remarkable comeback in trauma care—but is it here to stay? In this thought-provoking podcast, leading experts unpack the latest evidence comparing whole blood with component the...

6 Juli 25min

Switching from controlled to assisted ventilation: evidence, risks, and opportunities in AHRF?

Switching from controlled to assisted ventilation: evidence, risks, and opportunities in AHRF?

What are the benefits of moving from controlled to assisted mechanical ventilation in patients with Acute Hypoxemic Respiratory Failure (AHRF)? In this podcast, experts discuss the physiological ratio...

8 Juni 38min

Biomarkers in Severe Infections and Sepsis - Moving from Trials to the Bedside

Biomarkers in Severe Infections and Sepsis - Moving from Trials to the Bedside

Sepsis care is evolving fast. Are you keeping up? Don’t miss this podcast episode, where we explore the latest clinical trials reshaping antibiotic therapy for severe infections, from optimised treatm...

27 Maj 25min

Advanced Practice in Nursing and Allied Health Professionals

Advanced Practice in Nursing and Allied Health Professionals

What does advanced practice really look like in the ICU? In this podcast episode, we are joined by two advanced intensive care practitioners who share their roles, career journeys, and impact within t...

13 Maj 43min

Populärt inom Business & ekonomi

framgangspodden
varvet
rss-jossan-nina
rss-borsens-finest
uppgang-och-fall
badfluence
24fragor
rss-inga-dumma-fragor-om-pengar
avanzapodden
rss-dr-bjorklund
lastbilspodden
bathina-en-podcast
tabberaset
rss-kort-lang-analyspodden-fran-di
fill-or-kill
rikatillsammans-om-privatekonomi-rikedom-i-livet
kapitalet-en-podd-om-ekonomi
rss-dagen-med-di
borsmorgon
rss-hos-psykologen