Spermidine – The Powerful AntiAging compound you’ve never heard of but is about to take the world by storm

Spermidine – The Powerful AntiAging compound you’ve never heard of but is about to take the world by storm

Primeadine
Spermidine – The Powerful AntiAging compound you’ve never heard of but that is about to take
the world by storm. In this episode I sit down with Leslie Kenny the CEO and Founder of
OxFord Healthspan – a company founded for the purpose of bringing powerful healthy/anti
aging compounds to market. Today we deep dive into their first entry which is rooted in
ancient knowledge and yet relatively new to the modern world. Consider that this compound
hits at least 5 of the 9 hallmarks of aging….even better, new research seems to point to its
ability to improve immune response in elderly adults by helping certain areas of the immune
system to reboot and rejuvenate!! Oxford Span is committed to making this
supplement available to as many people as possible – for the month of December you can
benefit from introductory pricing PLUS an additional 15% discount (BIONAT15 promo code). If
you are this after December 2020 the discount code will still work!!
Note that this supplement will produce most noticeable results in the 50+ crowd who are
already seeing a decline in endogenous spermidine production and is not appropriate for
people with celiac disease or severe wheat allergies – we talk about all this and more in the
episode….enjoy!!
6:08
Leslie’s story – from autoimmune disease & infertility to how she first came across spermidine
7:22
The link between ancient Japanese scrolls on longevity and sexual intimacy and spermidine
11:05
Compounds that target the 9 hallmarks of aging and the 5 specifically targeted by Spermidine
13:30
Dietary sources and the reason why supplement companies are having to extract spermidine
from wheat instead of Natto
15:30
Natto – possibly the best and most economical source of spermidine
17:33
Who should NOT use the current Spermidine supplements (including Primeadine) and why
18:02
Amount of gluten per serving vs a slice of
19:54
Why the 50+ crowd is likely to experience the best visible results from Primeadine
20:55

Endogenous and exogenous sources of spermidine
22:57
The physical signs that your spermidine production is declining
28:20
Short, medium and long term benefits
36:05
Maximum dose as determined by regulatory bodies
38:49
Getting back to the ancient Daoist Scrolls – the aging male’s advantage over women

45:29
Best time of day to take Primeadine
50:27
DO NOT mix with hot foods or beverages
52:25
Introductory pricing in place until December 31, 2020
15% discount code in place for December and the new year: BIONAT15
Website:
Primeadine.com or OxfordHealthSpan.com

Just a few of the growing list of studies assessing Spermidine’s possible benefits for human
and longevity
Studies/References
Effect on Hormones, Fertility in men and women
The regulatory effect of biogenic polyamines spermine and spermidine in men and women. Open
Journal of Endocrine and Metabolic Diseases, 9(03), 35
Spermidine Intake and Longevity in humans
Higher spermidine intake is linked to lower mortality: a prospective population-based study. The
American journal of clinical nutrition, 108(2), 371-380
The autophagy enhancer spermidine reverses arterial aging in aged mice. Mechanisms of ageing
and development, 134(7-8), 314-320.

Okamoto, A., Sugi, E., Koizumi, Y., Yanagida, F., & Udaka, S. (1997). Polyamine content of ordinary
foodstuffs and various fermented foods. Bioscience, biotechnology, and biochemistry, 61(9), 1582-
1584
Ramot, Y., Tiede, S., Bíró, T., Bakar, M. H. A., Sugawara, K., Philpott, M. P., ... & Paus, R. (2011).
Spermidine promotes human hair growth and is a novel modulator of human epithelial stem cell
functions. PLoS One, 6(7), e22564
Rinaldi, F., Marzani, B., Pinto, D., & Ramot, Y. (2017). A spermidine-based nutritional supplement
prolongs the anagen phase of hair follicles in humans: a randomized, placebo-controlled, double-
blind study. Dermatology Practical & Conceptual, 7(4), 17.
Schwarz, C., Horn, N., Benson, G., Calzado, I. W., Wurdack, K., Pechlaner, R., ... & Flöel, A. (2020).
Spermidine intake is associated with cortical thickness and hippocampal volume in older adults.
NeuroImage, 221, 117132
Dietary polyamine intake and colorectal cancer risk in postmenopausal women. The American
journal of clinical nutrition, 102(2), 411-419

And finally an article on new findings of the effects of Spermidine on immune function is elderly
humans:
https://www.longevity.technology/autophagy-in-t-cells-maintained-by-
spermidine/?utm_source=ZohoCampaigns

Please note that this content is intended for information purposes only and is not intended to substitute professional medical advice, diagnosis or treatment. Always seek the advice of your physician or care provider with any questions or concerns you may have regarding a medical condition before you make any changes.

Avsnitt(366)

#320: Master Muscle Mass At Any Age: How Bioavailable Peptides Are Revolutionizing Muscle Repair, Improving Gut Health, & Supporting Immune Function With Michael Antonelli

#320: Master Muscle Mass At Any Age: How Bioavailable Peptides Are Revolutionizing Muscle Repair, Improving Gut Health, & Supporting Immune Function With Michael Antonelli

In this episode of the Longevity Podcast, I'm thrilled to be joined by industry innovator Michael Antonelli, Founder & CEO of Healthgevity. Together, we dive deep into cutting-edge strategies for optimizing metabolism, muscle health, and immunity.  Try Healthgevity and use promo code: NAT10.   What We discuss: Michael Antonelli's background and journey ... 00:07:41 The inspiration behind Healthgevity ... 00:10:24 Introduction to metabolic health ... 00:19:16 Discussion on Ignite 2.0 formulation ... 00:20:16 Dosing flexibility of Ignite 2.0 ... 00:23:48 DNF10 and its role in Ignite 2.0 ... 00:30:10 Building muscle with longevity supplements ... 00:31:09 Introduction to PeptiStrong and its benefits ... 00:32:33 The importance of gut health and immunity ... 00:41:43 Prime Gut Health formula details ... 00:42:15 Discussion on Biorepair ... 00:55:56 Introduction to Immuno Reboot ... 01:00:37 Importance of sleep and Serenity product ... 01:02:26 Details on Serenity formulation ... 01:05:00 Conclusion and where to find Healthgevity products ... 01:11:37   Our Amazing Sponsors: Young Goose L.A.D.R. Serum -  Powered by light-activated DNA repair enzymes, NAD+, and collagen peptides, it reverses damage while you go about your life. Sunlight? Red light therapy? It all helps this serum work smarter, not harder. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you’re an existing customer. Future-proof your face.   Quantum Upgrade - Imagine plugging yourself into a limitless power source. It’s been rigorously tested and shown to improve blood flow, reduce stress, and boost cellular energy by up to 29%. Try it today at quantumupgrade.io/NAT and start running life, instead of life running you. Use code NAT10 to get a 15-day free trial on the All-in-One Frequency Bundle. Good through June 1st, 2025.   Wizard Sciences (Neural Rx) - Neural Rx isn’t just about a quick boost. It’s designed to protect your brain long-term. With C60 (an antioxidant) and anti-inflammatory benefits, it combats oxidative stress and helps keep those brain cells healthy and happy. Plus, it supports mitochondrial efficiency, meaning more energy and focus for the long haul. Use code NAT15 at checkout to get 15% off your purchase. Visit wizardsciences.com.   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

25 Mars 1h 14min

#319: Why You Need HONEY: Exploring the Medicinal Powers of Honey for Health and Longevity

#319: Why You Need HONEY: Exploring the Medicinal Powers of Honey for Health and Longevity

As a holistic nutritionist and epigenetic coach, I'm always looking for ways to blend modern biohacking techniques with timeless ancestral wisdom to help you take charge of your health and longevity. In this episode, we're diving deep into the wonders of honey—not just as a sweetener, but as a powerful healing agent that's been revered for centuries.    Products mentioned in the episode: Manukora - Visit http://manukora.com/NAT and use code NAT Beekeepers Naturals - Propolis Throat Spray Wyse Earth - Visit https://wyseearth.com/ and use code Longevity10 for 10% off Living Libations   What I discuss: The Unique Qualities of Honey ... 00:02:33 Honey's Medicinal Uses Through History ... 00:04:25 Living Libations' Honey Products ... 00:06:00 Wound Healing with Honey ... 00:07:15 Honey's Antimicrobial Properties ... 00:08:45 Honey in Endurance Activities ... 00:10:20 Trehalose and Its Benefits ... 00:12:05 Honey's Antioxidant Properties ... 00:14:00 MGO and Antibacterial Effects in Honey ... 00:15:45 Anti-inflammatory and Immune Support from Honey ... 00:17:50 Prebiotic Effects of Honey ... 00:19:20 Manuka Honey's Cancer Research ... 00:20:40   Our Amazing Sponsor: Just Thrive - 99% of probiotics on the market die in your stomach before they even reach your gut. Just Thrive is the only probiotic guaranteed to arrive 100% alive where you need it most. Visit JustThriveHealth.com and use code NAT20 for 20% off your first 90 day bottle.   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

21 Mars 30min

#318: Lies He Taught In Medical School: The METABOLIC Secret To Reversing Chronic Disease with Dr. Robert Lufkin

#318: Lies He Taught In Medical School: The METABOLIC Secret To Reversing Chronic Disease with Dr. Robert Lufkin

In today's episode, I'm thrilled to share a captivating conversation with Dr. Robert Lufkin, a distinguished physician and medical school professor.  Dr. Lufkin, the author of the groundbreaking book "Lies I Taught in Medical School," offers unique insights from his perspective within the medical establishment. We dive deep into the shortcomings of modern medicine, especially when it comes to addressing chronic diseases like obesity, diabetes, and cardiovascular issues.    What We discuss: Dr. Lufkin's Background and Perspective ... 00:07:21 Modern Medicine and Chronic Disease Challenges ... 00:11:48 Dr. Lufkin's Personal Health Journey ... 00:13:37 Importance of Lifestyle in Medical Treatment ... 00:17:39 Type 2 Diabetes and Aging ... 00:28:11 Perspective on Cardiovascular Health ... 01:01:16 Discussion on Statins ... 01:04:16 General Practitioner Role and Medical System ... 00:21:33 Diet and Nutritional Insights ... 00:43:23 Fasting and Metabolic Health ... 00:51:15 Stress Management and Childhood Events Impact ... 00:38:45 Dr. Lufkin's Views on Supplements ... 01:09:35 Where to Find Dr. Robert Lufkin's Book ... 01:12:25   Our Amazing Sponsors: Profound Health - Nature’s Marvels have been making bioregulators for over a decade, working directly with Prof. Khavinson, the pioneer of Bioregulator science! They’re manufactured in the UK. They’re GMP and HACCP certified and FDA-compliant. Whatever your health needs, there’s a bioregulator for you. Head to profound-health.com and use code NAT15 for 15% off your first order.  Puori - 21 grams of high-quality whey protein from pasture-raised cows with no hormones, GMOs, or pesticides. Ready to ditch the questionable protein powders? Visit Puori.com/NAT and use my code NAT to get 20% off your first order! Timeline - Improve your cellular energy, strengthen muscle, and boost endurance by taking Mitopure daily. Mitopure unlocks 6x more Urolithin A than diet alone. Visit timeline.com/nat10 for 10% off.   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

18 Mars 1h 14min

#317 How Nitric Oxide Supports Digestion, Circulation, and Sexual Function in Men & Women With Cathy Eason

#317 How Nitric Oxide Supports Digestion, Circulation, and Sexual Function in Men & Women With Cathy Eason

Today, Cathy Eason, MS, BCHN and Clinical Education Director at Berkeley Life, fills us in on the MANY functional benefits of nitric oxide. We’re diving deep into the fascinating world of nitric oxide—a tiny yet mighty molecule that's essential for a myriad of bodily functions such as blood flow, energy production, and hormone regulation.    Offer for NEW and EXISTING Customers: New customers - visit berkeleylifeprofessional.com/NAT and enter code SAVE20 to save $20 off your first order. Existing customers of Berkeley Life Pro - email info@berkeleylife.com and tell them Nathalie sent you and you will get a free pack of the Prebiotic Nitrate Chewing Gum we talk about in the episode.   What We discuss: Importance and functions of nitric oxide ... 00:00:45 Decline of nitric oxide production with age and dietary sources ... 00:08:23 Challenges with nitric oxide production: genetics, age, and lifestyle ... 00:17:55 Impacts of lifestyle choices on nitric oxide levels ... 00:22:10 Role of nitric oxide in digestion, sexual health, and immune regulation ... 00:29:09 Relevance of mitochondria and energy production with nitric oxide ... 00:38:12 Link between nitric oxide and metabolic balance ... 00:49:05 Supplementation options and Berkeley Life's approach ... 00:54:06 Using the Berkeley Life gum to support oral biome ... 01:08:55 Details on special offers for listeners ... 01:13:08   Our Amazing Sponsors: Wizard Sciences (Neural Rx) - Neural Rx isn’t just about a quick boost. It’s designed to protect your brain long-term. With C60 (an antioxidant) and anti-inflammatory benefits, it combats oxidative stress and helps keep those brain cells healthy and happy. Plus, it supports mitochondrial efficiency, meaning more energy and focus for the long haul. Use code NAT15 at checkout to get 15% off your purchase. Visit wizardsciences.com.   BEAM Minerals - These minerals come from humate, a natural substance formed over millions of years as freshwater plants broke down and deposited their nutrients into the soil. Over time, those minerals concentrated into this black, crystalline material that’s now one of the most mineral-dense substances on earth. That’s what’s going into your body—and your cells absorb it within minutes. Visit beamminerals.com/NAT20 and use code NAT20 for 20% off.   Young Goose L.A.D.R. Serum -  Powered by light-activated DNA repair enzymes, NAD+, and collagen peptides, it reverses damage while you go about your life. Sunlight? Red light therapy? It all helps this serum work smarter, not harder. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you’re an existing customer. Future-proof your face.   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

14 Mars 1h 15min

#316: The Science of Joy: How Darkness and Sound Therapy Can Shift Your Entire Being Towards Happiness and Contentment With Pavel Stuchlik

#316: The Science of Joy: How Darkness and Sound Therapy Can Shift Your Entire Being Towards Happiness and Contentment With Pavel Stuchlik

Today we get to immerse ourselves into the realm of joy and self-discovery with our special guest, Pavel Stuchlik. Pavel, an ex-professional cyclist and a dynamic human optimization expert, joins us to share insights into living a life full of happiness and coherence.  Offer from Pavel: Here is lifetime FREE community with 7 day commitment to you. There are videos, courses, and a wonderful community that awaits you. - https://www.skool.com/systemreset   What We discuss: Pavel's Story and Journey ... 00:07:01 Darkroom Experience and Revelation ... 00:11:55 The Concept of NOA AON ... 00:14:44 Solfeggio Frequencies and Their Impact ... 00:15:14 Quantifying Emotional and Mental Shifts ... 00:18:42 Unhooking Process and Its Importance ... 00:21:06 Importance of Dreaming and Visualization ... 01:03:31 Physical Health and Biohacking Benefits ... 01:04:12   Our Amazing Sponsors: Quantum Upgrade - Imagine plugging yourself into a limitless power source. It’s been rigorously tested and shown to improve blood flow, reduce stress, and even boost cellular energy by up to 29%. Visit quantumupgrade.io/NAT and start running life, instead of life running you.Use my code NAT10 to get a 15-day free trial on the All-in-One Frequency Bundle. Good through June 1st, 2025   Manukora.com/NAT - Supports immunity and gut health with high levels of antioxidants and prebiotics and MGO powerful antimicrobial compounds. 70% of the antioxidants found in Manukora honey are not found in any other honey! Head to Manukora.com/NAT to get $25 off the Starter Kit, which comes with an MGO 850+ Manuka Honey jar, 5 honey travel sticks, a wooden spoon, and a guidebook!   LVLUP: The secret to CREvolution? It’s all about GAA. This powerful compound helps you get more creatine into your cells faster than traditional creatine. Ready to crush your next workout? Head to lvluphealth.com and use the code NAT for 15% off.   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

11 Mars 1h 11min

#315: Molecular Hydrogen: Tiny Molecule, Massive Health Impacts and So EASY to Add to Your Routine With Nathalie Niddam

#315: Molecular Hydrogen: Tiny Molecule, Massive Health Impacts and So EASY to Add to Your Routine With Nathalie Niddam

Join me as I explore this tiny yet incredibly powerful molecule that offers a plethora of health benefits. From its ability to manage inflammation and oxidative stress to enhancing exercise performance and recovery, molecular hydrogen is a fascinating subject in the realm of biohacking and longevity.    Hydrogen Products Mentioned: Hyest - https://www.hyestvitamins.com/?ref=LONGEVITY - Use Code: LONGEVITY for 10% off DrinkHRW - visit https://drinkhrw.com/superhuman use code LONGEVITY for 15% off   What We discuss: Hydrogen’s Unique Properties ... 00:01:00 Hydrogen Supplementation Methods ... 00:04:30 Preferred Hydrogen Tablets ... 00:07:00 Research and Human Studies on Hydrogen ... 00:10:00 Selective Antioxidant and Anti-inflammatory Benefits ... 00:13:00 Exercise and Recovery Benefits ... 00:16:00 Cardiovascular Health Benefits ... 00:17:30 Neuroprotective Effects ... 00:20:00   Our Amazing Sponsor: BiOptimizers - Magnesium Breakthrough -  BiOptimizers: It’s the only full-spectrum magnesium supplement with 7 unique forms of magnesium that your body can actually use and absorb. Go to  bioptimizers.com/bionat and enter the coupon code BIONAT to get 10% off your order.   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

7 Mars 31min

#314: The DARK Truth About Seed Oils, Cholesterol & Nutrition Myths—Revealed by Dr. Cate Shanahan

#314: The DARK Truth About Seed Oils, Cholesterol & Nutrition Myths—Revealed by Dr. Cate Shanahan

Welcome back, Longevity listeners! I’m excited to dive into today’s episode, in which we explore the controversial world of seed oils with the insightful Dr. Cate Shanahan, a Cornell-trained physician-scientist and author of Dark Calories. As a nutritionist and epigenetic coach, I'm thrilled to unpack the complex relationship between vegetable oils, cholesterol, and heart health with you all.   What We discuss: Dr. Cate Shanahan's journey into nutrition ... 06:38 Cate's perspective on medical training ... 10:56 Framework of the four pillars of traditional diets ... 17:16 Importance and challenges of modern food industry ... 25:06 Understanding processed foods and oxidation ... 27:24 Harmful effects of vegetable oils ... 33:00 Busting myths about cholesterol ... 42:10 Misconceptions about saturated fats and genetics ... 52:11 Dr. Cate's views on cooking oils ... 59:07 Balancing taste and health in cooking ... 01:06:36   Our Amazing Sponsors: Puori - 21 grams of high-quality whey protein from pasture-raised cows with no hormones, GMOs, or pesticides. Ready to ditch the questionable protein powders? Visit Puori.com/NAT and use my code NAT to get 20% off your first order!   Timeline - Improve your cellular energy, strengthen muscle, and boost endurance by taking Mitopure daily. Mitopure unlocks 6x more Urolithin A than diet alone. Visit timeline.com/nat10 for 10% off.   Just Thrive - 99% of probiotics on the market die in your stomach before they even reach your gut. Just Thrive is the only probiotic guaranteed to arrive 100% alive where you need it most. Visit JustThriveHealth.com and use code NAT20 for 20% off your first 90-day bottle.   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

4 Mars 1h 20min

#313 From Skeptic to Advocate: Todd Shipman on Quantum Energy, EMFs, and Unlocking All-Day Energy

#313 From Skeptic to Advocate: Todd Shipman on Quantum Energy, EMFs, and Unlocking All-Day Energy

I'm thrilled to welcome Todd Shipman, an advocate of quantum technologies, to join me today as we dive into the fascinating world of quantum energy. If you want to give it a try, risk-free, visit LeelaQ.com and use code NAT10 for 10% off all purchases. For QuantumUpgrade, visit quantumUpgrade.io and use code NAT15 for a 15-day free trial of the Quantum Upgrade. What We discuss:  Importance of quantum energy and its influential effects ... 00:07 Debunking myths and skepticism around quantum energy ... 00:09 Challenges of living in a non-natural technological world ... 00:11 Quantum energy as a harmonizing force in EMF exposure ... 00:15 Studies and research on Quantum energy effects ... 00:22 The user experience of quantum devices ... 00:28 Explanation of the Lila Quantum products ... 00:41 Discussion on quantum entanglement and Quantum Upgrade service ... 00:48 Todd Shipman's personal experience with food allergies and quantum energy ... 00:56 Access to the quantum field and available frequencies through Quantum Upgrade ... 01:02 Effects of Quantum Upgrade on energy and well-being ... 01:07   Our Amazing Sponsors: ProLon - Enjoy 5 days of nutrient-dense meals designed to mimic fasting without feeling deprived. You will feel AMAZING! Visit prolonlife.com/Nat to receive 20% off at checkout. If you’re in Canada you can go to Prolonfast.ca and use code NAT20 to save.   Young Goose - Youth Daily - activates your skin's anti-aging genes, shielding against environmental nasties by day and tackling signs of aging by night. Visit Younggoose.com and use code NAT10 on your first order, or, if you’re an existing customer 5NAT will reward you with an ongoing discount.   Wizard Sciences (Neural Rx) - Designed to protect your brain long-term. With C60 (an antioxidant) and anti-inflammatory benefits, it combats oxidative stress and helps keep those brain cells healthy and happy. Use code NAT15 at checkout to get 15% off your purchase. Visit wizardsciences.com.   Nat’s links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

28 Feb 1h 12min

Populärt inom Hälsa

somna-med-henrik
rss-bara-en-till-om-missbruk-medberoende-2
inga-beiga-morsor
alska-oss
sexnoveller-deluxe
johannes-hansen-podcast
angestpodden
brottarbroder
sova-med-dan-horning
not-fanny-anymore
en-beroendepodd-av-the-house
tyngre-traningssnack
sa-in-i-sjalen
rss-viktmedicinpodden
rss-sjalsligt-avkladd
dodsdomar
en-beroendepodd-av-the-house-2
rss-activation-podcast
halsoveckan-by-tyngre
smartare-fitness-podden