112 | Fyodor Urnov on Gene Editing, CRISPR, and Human Engineering

112 | Fyodor Urnov on Gene Editing, CRISPR, and Human Engineering

Not too long ago nobody carried a mobile phone; now almost everybody does. That's the kind of rate of rapid progress we're seeing with our ability to directly edit genomes. With the use of CRISPR-Cas9 and other techniques, gene editing is becoming commonplace. How does that work — and perhaps more importantly, how are we going to put it to use? Fyodor Urnov has worked in this area from its beginning, having coined the term "gene editing." We talk about how this new technology can be used to cure or prevent disease, as well as the pros and cons of designer babies.

Support Mindscape on Patreon.

Fyodor Urnov received his Ph.D. in Biology from Brown University. He is currently professor of Genetic, Genomics, and Development in the Department of Molecular and Cell Biology at UC Berkeley, as well as Director for Technology and Translation at the Innovative Genomics Institute. His research focuses on using CRISPR gene-editing techniques to develop treatments for sickle cell disease, radiation injury, and other conditions, as well as guiding IGI researchers as they bring these therapies from the lab to the clinic.

Todays episode is sponsored by The Great Courses Plus. Mindscape listeners get a free trial if they sign up at http://thegreatcoursesplus.com/mindscape.

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65 | Michael Mann on Why Our Climate Is Changing and How We Know

65 | Michael Mann on Why Our Climate Is Changing and How We Know

We had our fun last week, exploring how progress in renewable energy and electric vehicles may help us combat encroaching climate change. This week we're being a bit more hard-nosed, taking a look at ...

23 Sep 20191h 17min

64 | Ramez Naam on Renewable Energy and an Optimistic Future

64 | Ramez Naam on Renewable Energy and an Optimistic Future

The Earth is heating up, and it's our fault. But human beings are not always complete idiots (occasional contrary evidence notwithstanding), and sometimes we can even be downright clever. Dare we imag...

16 Sep 20191h 16min

63 | Solo -- Finding Gravity Within Quantum Mechanics

63 | Solo -- Finding Gravity Within Quantum Mechanics

I suspect most loyal Mindscape listeners have been exposed to the fact that I've written a new book, Something Deeply Hidden: Quantum Worlds and the Emergence of Spacetime. As I release this episode o...

9 Sep 20191h 50min

62 | Michele Gelfand on Tight and Loose Societies and People

62 | Michele Gelfand on Tight and Loose Societies and People

Physicists study systems that are sufficiently simple that it's possible to find deep unifying principles applicable to all situations. In psychology or sociology that's a lot harder. But as I say at ...

2 Sep 20191h 12min

61 | Quassim Cassam on Intellectual Vices and What to Do About Them

61 | Quassim Cassam on Intellectual Vices and What to Do About Them

All of us have been wrong about things from time to time. But sometimes it was a simple, forgivable mistake, while other times we really should have been correct. Properties that systematically preven...

26 Aug 20191h 10min

60 | Lynne Kelly on Memory Palaces, Ancient and Modern

60 | Lynne Kelly on Memory Palaces, Ancient and Modern

Memory takes different forms. Memories can be encoded in the strength of neural connections in our brains, but there's a sense in which photographs and written records are memories as well. What did p...

19 Aug 20191h 15min

59 | Adam Becker on the Curious History of Quantum Mechanics

59 | Adam Becker on the Curious History of Quantum Mechanics

There are many mysteries surrounding quantum mechanics. To me, the biggest mysteries are why physicists haven't yet agreed on a complete understanding of the theory, and even more why they mostly seem...

12 Aug 20191h 40min

58 | Seth MacFarlane on Using Science Fiction to Explore Humanity

58 | Seth MacFarlane on Using Science Fiction to Explore Humanity

Fiction shines a light on the human condition by putting people into imaginary situations and envisioning what might happen. Science fiction expands this technique by considering situations in the fut...

5 Aug 20191h 12min

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