112 | Fyodor Urnov on Gene Editing, CRISPR, and Human Engineering

112 | Fyodor Urnov on Gene Editing, CRISPR, and Human Engineering

Not too long ago nobody carried a mobile phone; now almost everybody does. That's the kind of rate of rapid progress we're seeing with our ability to directly edit genomes. With the use of CRISPR-Cas9 and other techniques, gene editing is becoming commonplace. How does that work — and perhaps more importantly, how are we going to put it to use? Fyodor Urnov has worked in this area from its beginning, having coined the term "gene editing." We talk about how this new technology can be used to cure or prevent disease, as well as the pros and cons of designer babies.

Support Mindscape on Patreon.

Fyodor Urnov received his Ph.D. in Biology from Brown University. He is currently professor of Genetic, Genomics, and Development in the Department of Molecular and Cell Biology at UC Berkeley, as well as Director for Technology and Translation at the Innovative Genomics Institute. His research focuses on using CRISPR gene-editing techniques to develop treatments for sickle cell disease, radiation injury, and other conditions, as well as guiding IGI researchers as they bring these therapies from the lab to the clinic.

Todays episode is sponsored by The Great Courses Plus. Mindscape listeners get a free trial if they sign up at http://thegreatcoursesplus.com/mindscape.

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61 | Quassim Cassam on Intellectual Vices and What to Do About Them

61 | Quassim Cassam on Intellectual Vices and What to Do About Them

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60 | Lynne Kelly on Memory Palaces, Ancient and Modern

60 | Lynne Kelly on Memory Palaces, Ancient and Modern

Memory takes different forms. Memories can be encoded in the strength of neural connections in our brains, but there's a sense in which photographs and written records are memories as well. What did p...

19 Aug 20191h 15min

59 | Adam Becker on the Curious History of Quantum Mechanics

59 | Adam Becker on the Curious History of Quantum Mechanics

There are many mysteries surrounding quantum mechanics. To me, the biggest mysteries are why physicists haven't yet agreed on a complete understanding of the theory, and even more why they mostly seem...

12 Aug 20191h 40min

58 | Seth MacFarlane on Using Science Fiction to Explore Humanity

58 | Seth MacFarlane on Using Science Fiction to Explore Humanity

Fiction shines a light on the human condition by putting people into imaginary situations and envisioning what might happen. Science fiction expands this technique by considering situations in the fut...

5 Aug 20191h 12min

57 | Astra Taylor on the Promise and Challenge of Democracy

57 | Astra Taylor on the Promise and Challenge of Democracy

"Democracy may not exist, but we'll miss it when it's gone" — or so suggests the title of Astra Taylor's new book. We all know how democracy falls short, in practice, of its lofty ideals; but we can a...

29 Juli 20191h 23min

56 | Kate Adamala on Creating Synthetic Life

56 | Kate Adamala on Creating Synthetic Life

Scientists can't quite agree on how to define "life," but that hasn't stopped them from studying it, looking for it elsewhere, or even trying to create it. Kate Adamala is one of a number of scientist...

22 Juli 20191h 12min

55 | A Conversation with Rob Reid on Quantum Mechanics and Many Worlds

55 | A Conversation with Rob Reid on Quantum Mechanics and Many Worlds

As you may have heard, I have a new book coming out in September, Something Deeply Hidden: Quantum Worlds and the Emergence of Spacetime. To celebrate, we're going to have more than the usual number o...

15 Juli 20191h 26min

54 | Indre Viskontas on Music and the Brain

54 | Indre Viskontas on Music and the Brain

It doesn't mean much to say music affects your brain — everything that happens to you affects your brain. But music affects your brain in certain specific ways, from changing our mood to helping us le...

8 Juli 20191h 15min

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