117 | Sean B. Carroll on Randomness and the Course of Evolution

117 | Sean B. Carroll on Randomness and the Course of Evolution

Evolution is a messy business, involving as it does selection pressures, mutations, genetic drift, and the effects of random external interventions. So in the end, how much of it is predictable, and how much is in the hands of chance? Today we're thrilled to have as a guest my evil (but more respectable, by most measures) twin, the biologist Sean B. Carroll. Sean is both a leader of the modern evo-devo revolution, and a wonderful and diverse writer. We talk about the importance of randomness and unpredictability in life, from the evolution of species to the daily routine of every individual.

Support Mindscape on Patreon.

Sean B. Carroll received a Ph.D. in immunology from Tufts University. He is currently the Andrew and Mary Balo and Nicholas and Susan Simon Endowed Chair of Biology at the University of Maryland, Vice-President for Science Education at the Howard Hughes Medical Institute, the Executive Director of HHMI Tangled Bank Studios, and Professor Emeritus of Genetics and Molecular Biology at the University of Wisconsin. His new book, A Series of Fortunate Events: Chance and the Making of the Planet, Life, and You, explores the role of chance in the development of life.


Avsnitt(418)

Bonus | Cuts to Science Funding and Why They Matter

Bonus | Cuts to Science Funding and Why They Matter

The Trump administration, led by Elon Musk and his Department of Government Efficiency, has proposed sweeping cuts to spending on science research here in the US, in particular at the National Institu...

12 Feb 20251h 10min

304 | James Evans on Innovation, Consolidation, and the Science of Science

304 | James Evans on Innovation, Consolidation, and the Science of Science

It is a feature of many human activities - sports, cooking, music, interpersonal relations - that being able to do them well doesn't necessarily mean you can accurately describe how to do them well. S...

10 Feb 20251h 16min

303 | AMA | February 2025

303 | AMA | February 2025

Welcome to the February 2025 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Pa...

3 Feb 20253h 44min

303 | James P. Allison on Fighting Cancer with the Immune System

303 | James P. Allison on Fighting Cancer with the Immune System

A typical human lifespan is approximately three billion heartbeats in duration. Lasting that long requires not only intrinsic stability, but an impressive capacity for self-repair. Nevertheless, thing...

27 Jan 20251h 7min

302 | Chris Kempes on the Biophysics of Evolution

302 | Chris Kempes on the Biophysics of Evolution

Randomness plays an important role in the evolution of life (as my evil twin will tell you). But random doesn't mean arbitrary. Biological organisms are physical objects, after all, and subject to the...

20 Jan 20251h 30min

301 | Tina Eliassi-Rad on Al, Networks, and Epistemic Instability

301 | Tina Eliassi-Rad on Al, Networks, and Epistemic Instability

Big data is ruling, or at least deeply infiltrating, all of modern existence. Unprecedented capacity for collecting and analyzing large amounts of data have given us a new generation of artificial int...

13 Jan 20251h 9min

300 | Solo: Does Time Exist?

300 | Solo: Does Time Exist?

A new year, and a new centennial -- 300 (regularly-numbered) episodes of Mindscape! Our tradition is to have a solo episode, and what better topic than the nature of time? Physicists and philosophers ...

6 Jan 20252h 11min

Holiday Message | Hits and Misses

Holiday Message | Hits and Misses

It's the end of the year, and time for our annual holiday break here at Mindscape. But as usual, we wrap up with a Holiday Message. This year, inspired by Joni Mitchell's "Hits" and "Misses" albums, I...

23 Dec 20242h 1min

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