Merel Kindt: How to Eliminate Phobias and PTSD Permanently

Merel Kindt: How to Eliminate Phobias and PTSD Permanently

Merel Kindt discusses how fear extinction can be achieved permanently, covering propranolol, epigenetics, psychedelics, and the broader implications of erasing fear. The conversation explores scientific approaches to phobias, PTSD, and future challenges in fear‑removal research.- 00:00 - Introduction to fear extinction- 14:07 - Propranolol and blood/brain barrier- 18:32 - Epigenetics and inherited fears- 26:33 - Removing fear of public speaking- 30:36 - PTSD- 33:45 - Psychedelics MDMA for self‑treatment- 37:29 - Pilot study with cigarette addiction- 42:31 - Should we get rid of fear? Consequences- 43:13 - MDMA vs LSD vs Psilocybin- 48:07 - Fear of silverfish- 50:13 - Modeling‑based phobias- 54:37 - Kindt 2009 paper on memory engrams- 55:34 - Kindt 2019 paper- 58:02 - Imagery scripting- 59:35 - Disgust removal?- 1:00:36 - How beta‑blockers work- 1:02:04 - Sleep for memory reconsolidation- 1:03:33 - Startle reflex measurement- 1:06:07 - Testing alternative beta‑blocker- 1:07:12 - Future challenges and limitationsSPONSORS:- Patreon: https://patreon.com/curtjaimungal- PayPal: https://bit.ly/2EOR0M4- Twitter: https://twitter.com/TOEwithCurt- Apple Podcasts: https://podcasts.apple.com/ca/podcast/better-left-unsaid-with-curt-jaimungal/id1521758802- Pandora: https://pdora.co/33b9lfP- Spotify: https://open.spotify.com/show/4gL14b92xAErofYQA7bU4e- Google Podcasts: https://play.google.com/music/listen?u=0#/ps/Id3k7k7mfzahfx2fjqmw3vufb44RESOURCES:- DOCUMENTARY SERIES: https://www.youtube.com/watch?v=pM3G6kITdYk- MEREL'S WEBSITE: https://kindtclinics.com/en/- http://betterleftunsaidfilm.com Theories of Everything with Curt Jaimungal features long-form, technically detailed interviews with leading researchers in physics, mathematics, consciousness, and philosophy, exploring topics at the level of active research. For academics, graduate students, and anyone seeking depth beyond popular science. SPONSOR: I subscribe to The Economist for their science and tech coverage. As a TOE listener, get 35% off! No other podcast has this: https://economist.com/TOE FOLLOW: Substack | Spotify | YouTube | Twitter Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices

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David Kaiser: MIT Physicist on Black Holes Older Than the Universe

David Kaiser: MIT Physicist on Black Holes Older Than the Universe

MIT physicist and historian David Kaiser examines primordial black holes, exploring how they might explain dark matter and connect to cosmic inflation. He discusses their potential impact on our under...

12 Maj 20251h 53min

Curt Jaimungal: Demystifying Godel's Theorem

Curt Jaimungal: Demystifying Godel's Theorem

Gödel’s incompleteness theorem is often misrepresented in popular science. In this episode we cut through the hype, correcting misconceptions from figures like Neil deGrasse Tyson, Veritasium, Michio ...

5 Maj 202524min

Ted Jacobson: The Proof That Gravity Equals Entropy

Ted Jacobson: The Proof That Gravity Equals Entropy

Ted Jacobson explains how Einstein's equations emerge from thermodynamic principles, proving gravity is entropic. The discussion explores Rindler horizons, quantum vacuum states, and holographic duali...

1 Maj 20251h 49min

Julian Barbour: What Happens When Physics Abandons Time Entirely

Julian Barbour: What Happens When Physics Abandons Time Entirely

Julian Barbour argues that time is an illusion and quantum mechanics should be replaced by relational ratios. He explores how entropy, consciousness, and the structure of the universe can be understoo...

29 Apr 20252h 22min

Curt Jaimungal: The Geometric Unity Iceberg

Curt Jaimungal: The Geometric Unity Iceberg

Curt Jaimungal unpacks Eric Weinstein's Geometric Unity in a three-hour mathematical deep dive. The episode serves as an extensive “iceberg” guide, moving from foundational concepts to advanced theory...

23 Apr 20253h 15min

Neil Turok: Black Hole Interiors Are Antimatter Mirrors (New Theory)

Neil Turok: Black Hole Interiors Are Antimatter Mirrors (New Theory)

Neil Turok proposes a radical black‑hole theory in which the interior is a mirror reflecting an antimatter twin, eliminating information loss, multiverses and extra dimensions. He explains the role of...

22 Apr 20252h 34min

Jennifer Nagel: Why Universal Skepticism Defeats Itself

Jennifer Nagel: Why Universal Skepticism Defeats Itself

Philosopher Jennifer Nagel argues that universal skepticism is philosophy’s greatest deception, claiming that doubt is an illusion and knowledge is a primitive instant recognition. We explore the natu...

19 Apr 20252h 43min

Curt Jaimungal: Debunking the All Possible Paths Myth

Curt Jaimungal: Debunking the All Possible Paths Myth

Curt Jaimungal debunks the popular “all possible paths” myth, explaining what Feynman’s path integral actually demonstrates and why the misconception endures. He also examines related misunderstanding...

17 Apr 202515min

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