Are GLP-1 Drugs "the Greatest Medical Breakthrough of the 21st Century"?

Are GLP-1 Drugs "the Greatest Medical Breakthrough of the 21st Century"?

In the past few years, we've learned that GLP-1 drugs don’t just help with diabetes or increase people’s feelings of fullness to help them lose weight. They have broad effects on substance abuse and behavior. They even seem to help with otherwise incurable illnesses, like Alzheimer's and schizophrenia. This month, a team of scientists studying 2 million patients in the Veterans Affairs medical system found that GLP-1s were associated with “a reduced risk of substance use and psychotic disorders, seizures, neurocognitive disorders (including Alzheimer’s disease and dementia), coagulation disorders (clotting), cardiometabolic disorders (like strokes and heart attacks), infectious illnesses and several respiratory conditions.” Today’s guest is a coauthor on the paper, Ziyad Al-Aly. He is a physician-scientist at Washington University in St. Louis. We talk about his new paper, the steps he took to make sure his findings were trustworthy, why GLP-1 drugs might work so well, what they’re teaching us about the brain and body, how they’re scrambling our sense of where volition begins and where free will ends, and what scientists should do next with the revelation that these drugs have effects that go far beyond obesity and diabetes. If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek Thompson Guest: Ziyad Al-Aly Producer: Devon Baroldi Links: Al-Aly et al. on the effectiveness and risks of GLP-1 drugs [link] Learn more about your ad choices. Visit podcastchoices.com/adchoices

Avsnitt(348)

Abortion Pills Are a Game Changer, Plus Our Next Big Culture War

Abortion Pills Are a Game Changer, Plus Our Next Big Culture War

In last week's instant reaction pod, Derek said he thought abortion pills were one of the most fascinating and important aspects of the end of the era of Roe. In this episode, he goes deeper into how ...

1 Juli 202237min

Five Reasons Everybody Is Wrong About a U.S. Recession—Including Me

Five Reasons Everybody Is Wrong About a U.S. Recession—Including Me

I feel like the theme of this podcast recently has been that everything is going off the rails: the Supreme Court, inflation, oil prices, air travel snafus. Take the economy, for example. My theory fo...

28 Juni 202237min

The End of Roe v. Wade Changes Everything

The End of Roe v. Wade Changes Everything

We react to the landmark Supreme Court decision and explain how it could affect the future of the court, national politics, fertility and family planning, state law, corporate policy, and more. To fur...

24 Juni 202242min

Why Air Travel Is a Hot Mess Right Now

Why Air Travel Is a Hot Mess Right Now

Lately, it feels like we’re surrounded by systems and industries that aren’t working the way they should. There's an oil shortage, and a baby formula shortage, and a used car shortage, and a microchip...

24 Juni 202242min

Why Gas Prices Are Skyrocketing—and an Ingenious Plan to Bring Them Down

Why Gas Prices Are Skyrocketing—and an Ingenious Plan to Bring Them Down

Expensive energy is an economic, psychological, and political scourge. Nominally, gas prices are at a record high. Adjusted for inflation, they could break the all-time record if they rise just anothe...

21 Juni 202245min

The Big Winners and Losers From the Remote Work Revolution

The Big Winners and Losers From the Remote Work Revolution

Most news is all about the immediate present. For instance, everything that is happening in the economy right now could be a historical anecdote in five years. But sometimes, norms change—and they sta...

17 Juni 202248min

The End of the Everything Boom (Plus: The Federal Reserve's Risky Move)

The End of the Everything Boom (Plus: The Federal Reserve's Risky Move)

This is a huge week for economic and finance news. On Wednesday afternoon, the Federal Reserve raised interest rates by 0.75 percentage points, its biggest move since 1994. Derek breaks down what this...

15 Juni 202240min

The Big Inflation FAQ: Why It’s So High, How Everyone Got It Wrong, and What's Next

The Big Inflation FAQ: Why It’s So High, How Everyone Got It Wrong, and What's Next

Inflation is the story that everybody keeps missing. In 2020, many people didn't expect inflation to rise. Wrong. In 2021, many expected inflation to be brief or "transitory." Wrong. Last month, many ...

13 Juni 202250min

Populärt inom Politik & nyheter

aftonbladet-krim
motiv
p3-krim
rss-krimstad
fordomspodden
rss-viva-fotboll
flashback-forever
svenska-fall
rss-sanning-konsekvens
aftonbladet-daily
svd-dokumentara-berattelser-2
spar
rss-krimreportrarna
rss-vad-fan-hande
rss-frandfors-horna
krimmagasinet
olyckan-inifran
rss-aftonbladet-krim
dagens-eko
grans