
The Link between Insulin Resistance and Depression – An interview with Dr. Natalie Rasgon
Metabolic dysfunction, such as insulin resistance and pre-diabetes, is closely associated with symptoms of depression. But how do we know if metabolic dysfunction causes depression? Or if metabolic therapies could treat depression? Those are more difficult questions to answer, but there is accumulating biological evidence that links insulin resistance and depressive disorders. Dr. Natalie Rasgon, a psychiatrist and clinician-researcher at Stanford University, published an important paper suggesting a possible causative role. Her research showed that measures of insulin resistance predicted the incidence of major depressive disorder. We discuss the background and findings of the study, as well as the take-home message–screening for and treating metabolic dysfunction can improve symptoms of depression. Experts featured in this video: Natalie Rasgon, MD PhD Professor of Psychiatry and Behavioral Sciences at Stanford University https://profiles.stanford.edu/natalie-rasgon Articles referenced in this video: Incident major depressive disorder predicted by three measures of insulin resistance: A Dutch cohort study https://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.2021.20101479 Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind™ is a nonprofit initiative incubated by Baszucki Group. Our mission is to provide education and resources in the emerging field of metabolic psychiatry, including ketogenic interventions for mental disorders. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #KetoForMentalHealth #MetabolicPsychiatry #BipolarTreatment #MetabolicNeuroscience #KetogenicMetabolicTherapy #DepressionTreatment#NutritionalKetosis#MentalIllnessTreatment#MentalHealthIsMetabolicHealth#BipolarDiet#insulinresistance #InsulinResistanceDepression#TreatmentResistantDepression
6 Apr 202327min

Keto for Brain Health – A Dramatic Personal Journey
Here's an inspiring story of one family using nutritional ketosis to treat dementia and eventually regain their lives. While everyone may not have as dramatic benefits from a keto diet, Mary and her daughter Suzi demonstrate what's possible. Born with Down's Syndrome, Suzi lived with cognitive delay but was always able to enjoy her life and her family. Then, at the age of 43, dementia set in, and her family's life changed, seemingly forever. But then Mary found Dr. Anette Bosworth and learned about nutritional ketosis. The rest is a heartwarming and motivational story that highlights the power of this metabolic nutritional intervention. Published case report: Case report: Ketogenic diet acutely improves cognitive function in patient with Down syndrome and Alzheimer’s disease https://www.frontiersin.org/articles/10.3389/fpsyt.2022.1085512/full Featured in this video: Dr. Annette Bosworth Youtube: https://www.youtube.com/user/annettebosworthmd Twitter: https://twitter.com/AnnetteBosworth Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind™ is a nonprofit initiative incubated by Baszucki Group. Our mission is to provide education and resources in the emerging field of metabolic psychiatry, including ketogenic interventions for mental disorders. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #KetoForMentalHealth #MetabolicPsychiatry #alzheimerdisease #dementia #dementiacare #downsyndrome #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis#MentalHealthIsMetabolicHealth
4 Apr 202339min

Metformin, Insulin Resistance and Bipolar depression: From research to clinical care
Dr. Cynthia Calkin's study using Metformin in treatment-resistant Bipolar Disorder showed that improving insulin resistance dramatically improved depression outcomes. This research is helping shift the paradigm for how we treat bipolar disorder. Her clinical practice and research studies demonstrate that metabolic dysfunction significantly contributes to mental illness and, perhaps even more importantly, that treating metabolic dysfunction results in significant symptomatic improvements. This is a dramatic clinical shift in psychiatry, and as you will hear, it has been slow to catch on within the psychiatry community. But with Dr. Calikn’s research and her desire to help as many people as possible, Dr. Calkin is helping spread the word so more clinicians understand the benefit of approaching patients from a metabolic perspective. Studies referenced in this video: Treating Insulin Resistance With Metformin as a Strategy to Improve Clinical Outcomes in Treatment-Resistant Bipolar Depression (the TRIO-BD Study): A Randomized, Quadruple-Masked, Placebo-Controlled Clinical Trial https://pubmed.ncbi.nlm.nih.gov/35120288/ Insulin Resistance and Blood-Brain Barrier Dysfunction Underlie Neuroprogression in Bipolar Disorder https://pubmed.ncbi.nlm.nih.gov/34113269/ Table of Contents: 0:00 - Introduction 1:57 - Interview with Dr. Cynthia Calkin 46:06 - Conclusion Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind™ is a nonprofit initiative incubated by Baszucki Group. Our mission is to provide education and resources in the emerging field of metabolic psychiatry, including ketogenic interventions for mental disorders. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. #MetabolicMind #KetoForMentalHealth #MetabolicPsychiatry #BipolarTreatment #BipolarDepression #InsulinResistanceBipolar #MetforminForBipolar #TrioBDStudy. #MetabolicNeuroscience #KetogenicMetabolicTherapy #DepressionTreatment #NutritionalKetosis #MentalIllnessTreatment #MentalHealthIsMetabolicHealth #BipolarDiet
24 Mars 202345min

Researcher with Bipolar Shatters Stigma
If you or a loved one lives with bipolar disorder, this podcast is one you don’t want to miss. Dr. Iain Campbell is a shining example of what “success” looks like in treating serious mental illness. For years, Dr. Campbell took medications to minimize his most serious symptoms of Bipolar Disorder but never felt well. Then, by chance, he tried a ketogenic diet, which, as he describes it, “turned the lights back on” and radically changed his life. Since then, he became a researcher in metabolic psychiatry, a husband, a father, and a consistent role model for those with bipolar disorder. Dr. Campbell has a Ph.D. in global health from the University of Edinburgh and is a researcher at the University of Edinburgh. He is the co-principal investigator of the first European trial of a ketogenic diet for Bipolar Disorder and is the recipient of the inaugural Baszucki Brain Research Fund Metabolic Psychiatry Research Fellowship. He co-hosts the Bipolarcast podcast and frequently speaks about his experience with bipolar. His openness is helping transform the way we publicly talk and think about bipolar disorder. Dr. Campbell has a rare combination of personal knowledge and experience combined with a deep scientific understanding that will help revolutionize the treatment of Bipolar disorder. Bipolarcast on Youtube https://www.youtube.com/channel/UCDB-iMvEJ-HeHqpamIN5JWw/videos?view=0&sort=dd&shelf_id=0 Twitter @iaincampbellphd https://twitter.com/IainCampbellPhD?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Eauthor Website https://ketobipolar.com/ About us: Metabolic Mind™ is a nonprofit initiative incubated by Baszucki Group. Our mission is to provide education and resources in the emerging field of metabolic psychiatry, including ketogenic interventions for mental disorders. Join our mailing list and learn more about metabolic psychiatry at https://metabolicmind.org/ Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
24 Mars 202331min

Metabolic Mind: Metabolism and Mental Health
Metabolic Mind is a non-profit initiative providing education & resources at the intersection of metabolic & mental health. Metabolic interventions like nutritional ketosis are being used to treat serious mental illnesses like Bipolar Disorder, Schizophrenia, & Major Depressive Disorder. We are here to help you learn if a ketogenic lifestyle could help you or a loved one living with a mental disorder improve your quality of life, or even send your psychiatric symptoms into remission. Watch our videos at https://www.youtube.com/@metabolicmind Our channel is for information only. Consult your physician before changing your lifestyle or medications.
24 Mars 20234min