Your Brain on Cocaine - The SHOCKING Truth About Dopamine!

Your Brain on Cocaine - The SHOCKING Truth About Dopamine!

In this video, I uncover the secrets behind cocaine's manipulation of our dopamine system, which plays a pivotal role in reward, motivation, and addiction. Whether you're curious about the science or looking to understand the mechanics behind addiction, this video is your starting point.We'll explore how cocaine, in its many forms like cocaine hydrochloride, freebase, and crack, disrupts your brain's delicate balance. By blocking the dopamine transporter, cocaine creates a dopamine overload, leading to euphoria and stimulation. However, this seemingly pleasant effect harbors a darker consequence. Our deep dive doesn't stop at dopamine.We'll traverse various brain regions influenced by cocaine, witnessing its impact on the meso limbic system responsible for reward and reinforcement, and the mesocortical system overseeing decision making and impulse control. The stakes are high as we venture into the realms of stress and arousal, exploring how cocaine tips the balance and intensifies norepinephrine release, contributing to increased heart rates and blood pressure and significantly elevating the risks of heart attacks or strokes.Chapters00:00:00 Introduction and Overview 00:00:44 Cocaine and the Dopamine System 00:01:25 Mechanism of Action: Dopamine Transporter (DAT) Blockage00:02:24 Neurotransmitter Spillover: Serotonin and Norepinephrine 00:03:33 Cocaine's Effects on Reward Pathway 00:04:16 Role of the Nucleus Accumbens and Amygdala00:05:21 Hippocampus and Memory Formation 00:06:17 Decision Making and Impulse Control: Mesocortical System00:07:02 Motor System and Nigrostriatal Pathway 00:07:54 Stress and Arousal: Hypothalamus 00:08:00 Conclusion

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Opioid use disorder and pregnancy

Opioid use disorder and pregnancy

Episode 18 of Cracking Addiction explores the management of opioid use disorder in pregnancy.Most women presenting with opioid dependence are of child-bearing age with chaotic drug use predisposes to amenorrhoea. The initiation of opioid substitution therapy (OST) facilitates stability and reinstatement of regular menstrual cycles and thus OST is a risk factor for unplanned pregnancy. About Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses availablehttps://www.meducate.com.au

1 Dec 202117min

Drugs of Concern

Drugs of Concern

Episode 17 of Cracking Addiction explores the range of drugs one can become dependent upon or addicted to and how to identify someone at risk of prescription drug aberrancy.About Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses availablehttps://www.meducate.com.au

24 Nov 202121min

How to take an accurate substance use history

How to take an accurate substance use history

How to take an accurate substance use history.Taking an accurate substance use history is of great importance in the management of addiction. There are a number of strategies that one could use but the most important part of history taking is that of demeanour and empathy. The best results and most accurate information are often obtained when one treats one’s patients with human empathy and in a non-judgemental manner. About Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses availablehttps://www.meducate.com.au

17 Nov 202115min

Methadone and it’s social benefits

Methadone and it’s social benefits

Cracking Addiction explores the social and societal benefits of Methadone. Methadone has a number of benefits that extend from not only the person taking it but also society as a whole. Methadone decreases criminality with the overall reduction in convictions and cautions estimated to be at 10% for each six months enrolled in methadone maintenance therapy with patients in continuous treatment receiving the best outcomes.

10 Nov 202115min

Methadone in Opioid Agonist Therapy

Methadone in Opioid Agonist Therapy

Ferghal & Thileepan explore the role of Methadone in opioid agonist therapy.

3 Nov 202113min

Opioid Replacement Therapy Part 1

Opioid Replacement Therapy Part 1

Episode 13 of Cracking Addiction covers opioid replacement therapy (ORT) and the philosophy and evidence behind this highly effective treatment for patients with opioid use disorder.

26 Okt 202119min

Dependence, Addiction and Opioid Use Disorder

Dependence, Addiction and Opioid Use Disorder

In this episode of Cracking Addiction we cover the difference between dependence and addiction, the intricacies of addiction and provide a definition of opioid use disorder

20 Okt 202113min

OPQRST

OPQRST

Cracking Addiction covers the OPQRST framework and how to use this framework to prescribe safely to patients on opioid medications.

13 Okt 202118min

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