Nature Podcast26 Mars 2025

New lasso-shaped antibiotic kills drug-resistant bacteria

In this episode:

00:46 Newly discovered molecule shows potent antibiotic activity

Researchers have identified a new molecule with antibiotic activity against a range of disease-causing bacteria, including those resistant to existing drugs. The new molecule — isolated from soil samples taken from a laboratory technician’s garden — is called lariocidin due to its lasso-shaped structure. The team say that in addition to its potent antibiotic activity, the molecule also shows low toxicity towards human cells, making it a promising molecule in the fight against drug-resistant infections.

Research Article: Jangra et al.

09:36 Research Highlights

A reduction in ships' sulfur emissions linked to a steep drop in thunderclouds, and the epic sea-voyage that let iguanas reach Fiji.

Research Highlight: Ship-pollution cuts have an electrifying effect: less lightning at sea

Research Highlight: Iguanas reached Fiji by floating 8,000 kilometres across the sea

13:54 Assessing the nuances of humans’ biodiversity impacts

A huge study analysing data from thousands of research articles has shown that the human impacts on biodiversity are large but are in some cases context dependent. The new study reveals that at larger scales, communities of living things are becoming more similar due to human influence, but at the smaller scale they are becoming more different. "These are generally unwanted effects on biodiversity," says study author Florian Altermatt, "this is one more very strong argument that stopping and reducing these pressures to halt and reverse biodiversity declines is needed."

Research article: Keck et al.

21:45 Briefing Chat

How a proposed green-energy facility in Chile could increase light pollution at one of the world’s most powerful telescopes, and how a calving Antarctic iceberg revealed an unseen aquatic ecosystem.

Nature: Light pollution threatens fleet of world-class telescopes in Atacama Desert

Scientific American: Stunning Antarctic Sea Creatures Discovered after Iceberg Breaks Away

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