The Dirty Secret Behind Ozempic: How It Wrecks Your Gut (Here’s How to Fix It) | Hannah Kleinfeld  : 1265

The Dirty Secret Behind Ozempic: How It Wrecks Your Gut (Here’s How to Fix It) | Hannah Kleinfeld : 1265

For decades, gut health was reduced to yogurt commercials and vague promises from probiotics that barely worked. But what if we’ve been targeting the wrong bugs, using the wrong delivery, and ignoring the true source of chronic inflammation and accelerated aging?

In this thought-provoking episode, Dave sits down with Hannah Kleinfeld, a leader in microbiome innovation, to expose why most probiotics fail—and how one company’s scientifically validated approach could redefine your gut, brain, immune system, and even your metabolism.

You’ll learn how dysbiosis may be wrecking your brain without you knowing it, why your probiotic likely died in your stomach acid, and the secret to rebooting your microbiome after antibiotics, GLP-1 drugs, or years of toxic exposure. This isn’t just about digestion—your gut controls your cravings, energy, sleep, mood, and aging trajectory.

So what’s the one upgrade that can actually reset your gut… for good?

What You’ll Learn in This Episode:

• Why your gut—not your brain—is making most of your decisions

• How 93% of probiotics on the market fail before they reach your intestines

• The “AB 10” protocol that rebuilds your gut after antibiotics or SIBO

• What GLP-1 weight-loss drugs are doing to your microbiome (and how to stop it)

• The shocking gut–brain–heart axis connection you’ve never heard of

• Why inflammation, brain fog, and mood swings may start with leaky gut

• Which probiotic strains are clinically proven to improve cognition and mood

• What to do if you want to eat gluten again—or survive American wheat

• How a fermented papaya concentrate could replace your acid reflux meds

• Why optimizing your gut could extend your lifespan by 40%


***Get 20% off your next purchase by going to https://omnibioticlife.com/pages/dave-asprey/ or omnibioticlife.com/dave***

SPONSORS

-Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.

-Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order.

Resources:

Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/

OMNi-BiOTiC's Instagramhttps://www.instagram.com/fatty15/

OMNi-BiOTiC's Website: https://omnibioticlife.com/

2025 Biohacking Conference: https://biohackingconference.com/2025

Danger Coffee: https://dangercoffee.com

Dave Asprey’s Website: https://daveasprey.com

Dave Asprey’s Linktree: https://linktr.ee/daveasprey

Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com

Own an Upgrade Labs: https://ownanupgradelabs.com

Upgrade Labs: https://upgradelabs.com

40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com


Timestamps:

00:00 – Trailer

03:15 – Intro

05:05 – Probiotics, Prebiotics, and Postbiotics Explained

08:21 – The Importance of Delivery Mechanisms

17:36 – Addressing SIBO and Gut Health Protocols

31:55 – The Impact of GLP-1 Drugs on Gut Health

39:26 – The Role of Gut Bacteria in Hunger and Fasting

40:01 – Painkillers and Gut Health: A Personal Experience

40:51 – The Dangers of Proton Pump Inhibitors

42:00 – The Importance of Stomach Acid

44:55 – Probiotics for Chronic Conditions

48:38 – The Impact of Glyphosate on Gut Health

57:04 – Alcohol and Gut Bacteria

01:02:01 – New Solutions for Acid Reflux

01:07:57 – The Future of Gut Health and Longevity

01:11:33 – Conclusion and Special Offer

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Avsnitt(1431)

How Whole Body Vibration Hacks Fitness & Fat Loss – Tony Molina : 963

How Whole Body Vibration Hacks Fitness & Fat Loss – Tony Molina : 963

IN THIS EPISODE OF THE HUMAN UPGRADE™...… you’ll learn how whole body vibration works and the many ways it benefits your physiology. It’s the nexus between energy and life, says Tony Molina, a performance optimization expert.“This biohack helps you burn more calories,” he says. “It helps you increase strength and reaction time. You can improve skin and circulation, bone density, pain relief, hormonal changes, posture and balance. It's also a lifelong health and longevity partner.” He’s talking about the Power Plate. He’s a high-altitude and longevity researcher and Senior Research and Development Specialist at the company.“Whole body vibration runs off Isaac Newton's second law, so force equals mass times acceleration,” he explains. “Where acceleration is what’s being increased versus mass. And generally, we focus on the mass, whether we do any kind of strength training, we focus on holding mass or dealing with the mass or changing the mass. With whole body vibration and Power Plate, you’re focusing on the acceleration or the speed change.”Other cool things about whole body vibration:You're changing the formula from conscious effort (like conventional exercise) to subconscious (harmonic vibration).You’re experiencing multiplanar movement that creates an unstable environment that’s proprioceptively challenging. (The nervous system doesn't know what to do, which is a good thing.)Your neuromuscular spindle gets stimulated without the need for the brain even to get involved. (Cognitive confidence!) Your nervous system itself is ramping up safety signals so the brain understands what it needs to do without you consciously having to do anything.Your reflexes improve; your reaction time gets better; your ability to propriocept allows your posture to improve; and you breathe better.Listen on to find out more about whole-body vibration training, therapy, and how it can make you live longer, whatever your fitness level or ability.SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: https://powerplate.com/dave to get 20% off a Power Plate® MOVE (save $659) AND a FREE Power Plate Pulse Massage Gun (valued at $249.99) WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Increase BDNF and Support Neurogenesis: Go to https://nootopia.com/davegenius, use code DAVE10 to get an extra 10% offA Cleaner Nicotine Alternative: https://lucy.co, use code DAVE20 for 20% off your first order of pouches, gums or lozengesCooler Temps for Deeper Sleep: https://www.chilisleep.com/, use code HUMANUPGRADE20 to save 20% on the Dock Pro Sleep System See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

5 Aug 202254min

How to Hack Your Metabolism and Power Your Energy – Michal Mor, Ph.D. : 962

How to Hack Your Metabolism and Power Your Energy – Michal Mor, Ph.D. : 962

IN THIS EPISODE OF THE HUMAN UPGRADE™...…you’ll learn about the critical role metabolism plays in your body’s energy and performance. Important new science findings about human metabolic health shows how you can change your metabolism. To help you make these changes, this episode gives you practical tips and tools for measuring your metabolism and ways to manage it effectively.Guest Michal Mor, Ph.D., co-founded Lumen with her twin sister, Merav Mor, Ph.D., and three long-time entrepreneur friends nearly a decade ago. As Chief of Metabolic Health & Science, Michal’s background includes degree studies in Medical Laboratory Sciences and Physiology with an emphasis on cardiac arrhythmia. The Lumen founders set out to close the gap of what existed in the science and something people could actually use to manage their metabolic health.Both Michal and her twin, Merav, were multiple-year Ironman participants. Athletic performance—and how to improve it—influenced their work with metabolism. Four years of research and development plus more years of validation studies and beta test users went into developing Lumen. Lumen is a hand-held device that accurately measures your metabolism through the breath. It uses a CO2 sensor and flow meter to measure the CO2 concentration in your breath, indicating if your body is in carb or fat burn.“So, this ability to shift between them, it's not only good for athletic performance it's also improving our quality of life,” Michal says. “It enables us to enjoy life to our fullest potential. It's about longevity. It's about being able to achieve our goals, not having those mood swings. This is so much more than improving athletic performance.”Lumen has accumulated a metabolic measurement database with over 20m measurements. These insights have shown how lifestyle habits affect metabolism and the body more than previously thought possible. Listen on to learn how with just one breath in the morning, you can set your metabolism course for the day and then monitor it throughout the day.SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: https://lumen.me, use code Asprey50 to get $50 off a Lumen deviceWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Experience the High Life with Infrared Therapy: https://higherdose.com and use code HUMAN10 for 10% off your entire purchase.Capture Life Force Energy: https://leelaq.com, use discount code DAVE10 to get 10% off sitewideBusiness Growth With SEO: https://www.stephanspencer.com, get a FREE consultationSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

2 Aug 20221h 6min

Mini-Episode: Cool Facts Friday #25

Mini-Episode: Cool Facts Friday #25

In this Episode of The Human Upgrade™...​Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.Tattoos can help monitor your blood pressure Device that protects against head injuries Upgrading your avocado toastWays to manage the harmful aging-inflammation duo Pee recycling does the soil goodEPISODE SPONSOR: The Eng3 NanoVi device helps repair oxidative stress damage and support the body’s natural repair mechanisms. https://eng3corp.com/DAVE/. Learn more: The Anti-Aging Science Behind the NanoVi Device – Rowena Gates & Hans Eng – #416.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

30 Juli 202212min

How to Fix Your Brain When It’s Tired, Wired and Slow – Matt Gallant & Mr. Noots : 961

How to Fix Your Brain When It’s Tired, Wired and Slow – Matt Gallant & Mr. Noots : 961

IN THIS EPISODE OF THE HUMAN UPGRADE™... … you’ll find out why aging and stress are the major contributors to neurodegenerative diseases in your lifetime, what you can do to stave off the effects, and how you can kickstart your brain into functioning at a way higher level.You’ll also learn about:BDNF (Brain-Derived Neurotrophic Factor) and ways to increase itOptions for how you can support your brain’s neurogenesisHow certain mushrooms and collagen can be used to increase your cognitive function—so you can focus, concentrate and be more creativeHow customized nootropics can help you reach peak mental performance Matt Gallant keeps coming back on the show to introduce innovative supplements that work with your brain and body. We’ve talked about nootropics, psychobiotics, magnesium, enzymes, blood sugar, gut health and more. As co-founder of BiOptimizers, Matt makes important connections within body systems and finds unique ways to maximum human performance. After a personal health scare with his own brain, he’s turned his professional attention to hacking and upgrading the brain in as many ways as possible.Most people’s brains aren't at 100% due to many factors, he says, like lack of sleep, chronic high stress, an inadequate diet, and overuse of certain drugs and prescriptions.Mr. Noots, (scientist Mark Effinger) teamed up with Matt on this quest to support brain health and improve cognitive function. After a childhood exploring everything science, chemistry and physics, he joined the US Air Force and became an endurance athlete and bodybuilder. His life, like Matt’s, took an unexpected turn and he struggled with health issues. It took creative, performance-enhancing nutrition to get himself well. He’s now Chief Product Officer for the mind-enhancing compounds and stacks of nootropics at Nootopia and works side-by-side with Matt.Their newest product, CollaGenius, combines powerful mushroom extracts and collagen into a formula specifically to energize your brain and body. Collagen improves skin health, relieves joint issues, strengthens hair and nails, and prevents bone loss—and it also does your brain a lot of good. And here’s what the mushrooms do for you in the right amounts. That’s the key principle—the dose creates the effect. Lion’s Mane: Boosts BDNFChaga: A natural anti-inflammatory that supports immunityReishi: Alleviates stressCordyceps: Elevates athletic performance and maximizes brain health Together, Matt and Mr. Noots continue pushing limits and finding ways to make your brain operate at its highest capacity. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERSGo to https://nootopia.com/davegenius, use code DAVE10 to get an extra 10% off.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Mineral-Rich Salt with Micronutrients: https://oryxdesertsalt.com, learn more at the website and purchase through Whole FoodsA Cleaner Nicotine Alternative: https://lucy.co, use promo code DAVE20 for 20% off your first order of pouches, gums or lozenges.Isometrics for Cardiovascular Health: https://www.zona.com, use code DAVE2022 to get $150 off the Zona Plus See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

29 Juli 202258min

Psychedelic Upgrade: Finding the Right Dose & Approach – Dr. Phil Wolfson & Dr. Julie Holland : 960

Psychedelic Upgrade: Finding the Right Dose & Approach – Dr. Phil Wolfson & Dr. Julie Holland : 960

IN THIS EPISODE OF THE HUMAN UPGRADE™...…two psychiatric research pioneers open up about the benefits people experience from psychedelic treatments. From mental health conditions to crucial social connections, there’s a dose and approach that can work for you and with your own brain chemistry.Psychiatrist and psychotherapist Dr. Phil Wolfson, creator of Ketamine Assisted Psychotherapy, leads patients through psychedelic psychotherapy sessions, guiding them through their past and present in an open, altered state of mind. His invaluable work is the result of an intense, many-decades-long clinical practice. He focuses on new pathways for healing depression, PTSD, addiction and other conditions.“There’s really no right or wrong with psychedelics,” Dr. Wolfson says. “It’s about how do we integrate our lives and relationship in this very difficult time with people and in our beings, and what practices we bring to this whole thing. So, it’s not just about substances.” Psychiatrist and psychopharmacologist Dr. Julie Holland explains in her book, “Good Chemistry: The Science of Connection, From Soul to Psychedelics,” why you need connection, how you’ve lost it, and how you might find it again. She believes psychedelics can help. Taken under the direction of a trained psychiatrist, they can catalyze a connection with the self, nature, or the cosmos.Dr. Holland’s research—with a focus on the parasympathetic nervous system—dives into how you can “turn on” and “tune in” to the brain chemistry that supports connection. At the same time, you can tamp down the fight or flight mode that derails sleep, metabolism, libido and much more. She’s leading new understanding about how your behaviors are driven by the hormones and neurotransmitters that make up good (and bad) brain chemistry, including testosterone, estrogen, dopamine, serotonin and most crucially, oxytocin. If you liked this special episode with Phil and Julie, you’ll learn even more from listening to their full podcasts on these topics:Your Guide to Psychedelic Psychotherapy – Dr. Phil Wolfson with Dave Asprey – #770Psychedelics Offer New Solutions for Social Isolation – Dr. Julie Holland with Dave Asprey – #757WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Structure Water Molecules; Achieve Body/Brain Coherence: https://analemma-water.com, use code DAVE10 for 10% offComplete Brain Nutrition with Nootropics: https://neurohacker.com/dave, use code DAVE to score an extra 15% off Qualia MindHydrate with Electrolytes: https://DrinkLMNT.com/DAVE, get a FREE LMNT Sample Pack with 8 single-serving packets for the cost of shipping ($5 for U.S. customers) See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

26 Juli 202233min

How Intuition Can Lead You To Your Highest Self – Joy Martina : 959

How Intuition Can Lead You To Your Highest Self – Joy Martina : 959

IN THIS EPISODE OF THE HUMAN UPGRADE™...…Dave’s travels take him to Amsterdam where he talks with psychic psychologist Joy Martina about intuition, hypnosis and joyful learning. Here’s some of the “how-to’s” you’ll learn about in this episode:How to find the right hypnotist for youHow to identify three common misperceptions about hypnosisHow to tap into your own intuition and tune into your own wisdomHow to recognize your body’s kinesthetic channel How to learn through joyful and pleasurable experiencesHow to listen to your gut just as much as your brainHow to use your energy for goodHow to draw from the quantum field How to connect to your highest potentialHo to create big change in your lifeHow to tune into your environment How to recognize the benefit from staying stuck in old patterns and make a shiftHow to notice your triggers and react less to themHow to move from an emotionally charged attached position to a grounded, neutral state.After this episode, head into the podcast library for Joy’s previous conversation with Dave: Intuition is Not a Feeling – #574.About Joy Martina: Joy Martina, psychic psychologist and a channeler of Christallin Consciousness specializes in high-level intuitive intelligence training for entrepreneurs, business owners and celebrities. She is an author, the creator of the Christallin Oracle Training, a master hypnotist and trainer of trainers.Must-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discountMattress Temperature Tech:https://www.eightsleep.com/dave, use code dave to save $250 on the Pod ProBusiness Growth With SEO:https://www.stephanspencer.com, get a FREE consultationSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

21 Juli 20221h 4min

How Sweden’s Herd-Immunity Approach Defied the World – Johan Anderberg : 958

How Sweden’s Herd-Immunity Approach Defied the World – Johan Anderberg : 958

IN THIS EPISODE OF THE HUMAN UPGRADE™...… Swedish journalist Johan Anderberg joins the show to talk about how he captured a rare moment in his country’s history during the worldwide COVID-19 pandemic in 2020.His book, “The Herd: How Sweden Chose Its Own Path Through the Worst Pandemic in 100 Years,” explains this unique time. In it, he gives a fly-on-the-wall account of the herd-immunity strategy that Sweden adopted during the first year of the pandemic. First, the government instituted no restrictions. Then, it declined to order that people wear face masks. While the rest of the world looked on with incredulity, condemnation, admiration, and even envy, Sweden stood alone in its decisions.“We have to value the fact that different countries do different things,” Johan says.Here’s what you’ll learn by listening:How the Swedish COVID-19 strategy veered far from what the rest of the world was doing.Why "The Swedish Experiment” has been alternately praised and held up as a cautionary tale.In what ways Sweden’s laissez-faire strategy with few restrictions worked.Differing perspectives—no judgment or right/wrong—about the actions and reactions of governments, communities and individual citizens during a medical crisis.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Save Time, Burn Fat, Build Muscle: Visit https://powerplate.com/Dave to save 20% off for a limited time and Probiotic Eases Stress: https://www.omnibioticlife.com/DAVE, use code DAVE20 to get 20% off receive a FREE Power Plate massage gun with purchase Sleep Better on Natural Memory Foam: https://myessentia.com, use code DAVEVIP to get an exclusive discountSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

20 Juli 202242min

Hacking Deep Sleep – Interventions With Dave – George Hanna : 957

Hacking Deep Sleep – Interventions With Dave – George Hanna : 957

In this Episode of The Human Upgrade™...​ … Dave talks with George Hanna about how to get better deep sleep.George says he’s been a health and fitness buff for most of his life. Now in his early 60’s, he’s adopted much of the biohacking lifestyle, including sleep hacks. Yet, deep sleep continues to elude him. He and Dave get into factors that could be messing with his circadian rhythm, like temperature, light, overtraining, heart rate variability, glucose monitoring, blood sugar and more. They also go over potential tweaks to:MushroomsHerbsAmino AcidsTestosteroneSupplementsThyroidStatinsIf you struggle with sleep or simply want to learn to fine-tune the sleep you’re getting, take a listen to this episode for tips and resources.Listen to the other episodes in the Interventions With Dave series and don’t miss the “Links & Resources” section on the episode web page: https://daveasprey.com/intervention-george-hanna-957/Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury.WE APPRECIATE OUR PARTNERS, CHECK THEM OUT!Over-the-head Pillow for Better Sleep: https://www.sleepcrown.com/dave to save $15 and get free U.S. shippingNAD+ for Brain Health: https://innovativemedicine.com/DAVE and save 20%Science-backed, Music-driven Breathwork: Go to https://www.othership.us/dave, sign up for the app and get two weeks free.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

14 Juli 202235min

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