The Dirty Secret Behind Ozempic: How It Wrecks Your Gut (Here’s How to Fix It) | Hannah Kleinfeld : 1265

In this Episode of The Human Upgrade™...​… Dave talks with Lisa B. about the frustration she’s experiencing with her health conditions. She says she lives a healthy lifestyle and does the “right things” and still struggles with chronic low energy. Her kids often say, “you never feel well, mom.” She agrees but finds it difficult to explain why. Now in her early 50s, she’s had panic attacks and anxiety since childhood and has taken many types of anti-depressants throughout her life. She also struggles with OCD.She’s experienced long-time hormonal imbalances, including painful periods, acne, fertility problems, and ongoing PMS “flu” that she says takes over her life during her cycles. She suffers from aggressive seasonal allergies and has a shellfish allergy. She’s been on Accutane, was diagnosed with Lupus in college and also diagnosed with exercise-induced urticaria and Mast Cell Activation Syndrome. She got COVID in 2021.In this “Interventions With Dave” episode, Dave examines what’s going on with Lisa’s varied symptom. They discuss what’s working and what’s not, and what can help her gain more energy and control of her health. The conversation gets into a bunch of topics, like:PMS “flu” (with sore throat, hot tongue, achy, brain fog, no energy, feverish feeling with no fever present, painful periods) Hormones, the Wiley Protocol and testosterone“Mold cough” and other symptoms of moldOCD and anxietyMTHFR gene mutation Histamine, Mast Cells and Mast Cell Activation SyndromeAllergiesAnd much more…Find biohacking tips, tools and resources particular to this episode on the episode web page: https://daveasprey.com/interventions-with-dave-lisa-b-949/Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

18 Juni 202259min

SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: Go to beamminerals.com/advancedset. Use code DAVE to get 20% off.IN THIS EPISODE OF THE HUMAN UPGRADE™... …you’ll find out how plant-based humic substances have the power to stop and reverse the effects of glyphosate damage in both humans and soil.Caroline Alan, co-founder and CEO of BEAM Minerals, explains how minerals provide your body systems with critical cellular support, how they get depleted and how you can replenish them. She goes even further to talk about glyphosate’s harmful effects on human health and soil health, particularly when it comes to minerals.In her former corporate career of software development and business consulting, Caroline experienced problems physically, mentally and energetically. She struggled with issues like life-long gluten intolerance, whole-body inflammation, leaky gut, chronic headaches, flat-lined adrenals and low thyroid. Her chronic health issues didn’t resolve until she began taking plant-based humic and fulvic minerals.This cellular support changed her life so dramatically, she started deep research into the science of minerals and co-founded BEAM Minerals. Then she kept going and began to look more closely at the current problems with farming in soils that have become unproductive due to a lack of microbial and mineral content. She investigated the effects of glyphosates on soils and in the human body and found:One of the root causes of unhealthy soil can be linked directly to glyphosate use in modern production farming.One of the root causes of mineral depletion and chronic illness in modern humans points directly to glyphosate ingestion.The bottom Line? We all have glyphosates in our bodies. Here's what it can do: Suppress critical enzymes, create gut dysbiosis, chelate minerals from your system, reduce mitochondrial function, and cross and affect the blood–brain barrier. Studies also show more use of glyphosate can lead to an uptick in chronic and acute health conditions.Research finds that plant-based humic and fulvic substances offset glyphosate harm. This conversation will help you recognize symptoms of mineral depletion in your own body. You’ll get practical tips about how to use 100% bioavailable, plant-based fulvic and humic mineral supplementation in easy forms like liquids and topical spray.BONUS: For research links and other resources about glyphosate and humic/fulvic substances, visit daveasprey.com/glyphosate.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Complete Spectrum Hemp + Chinese Herbs: https://radicalrootsherbs.com/DAVE, use code DAVE to get 10% offTasty Keto Bread & Chips: https://www.uprisingfood.com/DAVE, use code DAVE to get $10 off the starter bundle8th Annual Biohacking Conference: https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

17 Juni 202249min

IN THIS EPISODE OF THE HUMAN UPGRADE™... … you’ll get tips about how to lead a brain healthy lifestyle and how to keep perspective along your own entrepreneurial journey. Activism, acting and entrepreneurship are wired into Patrick Schwarzenegger’s DNA. He thoughtfully balances each passion through his work as an Alzheimer’s advocate, actor, investor and food founder. Patrick’s known for his trend-spotting abilities in the better-for-you food and beverage industry. He got into the fast-casual Blaze Pizza franchise when he was just a teen. That experience solidified his interest in health and wellness: “invest solely into entrepreneurs and companies that were providing Americans with the healthier alternative." He’s now an active investor and advisor to numerous brands and helps founders scale their emerging businesses to the next level.His latest venture encourages brain health at every age and supports programs, research, and lifestyle choices designed to make your brain work better. Patrick co-founded a new brain health food brand called “MOSH” with his mom, Maria Shriver, designed specifically to up-level your brain function.“We really want it to be a brand that was created out of a mission and out of the why, and not so much the what,” Patrick says. … “We want to be a brain health company and also educate consumers and raise money and donate that to the Women's Alzheimer's Movement. So, it's been an amazing journey.”A journey with its share of mishaps, too: “We had so many things that went wrong and that was kind of the fun part was learning about that and finding ways to fix it. That's wanting to be an entrepreneur or that's embarking on that journey, you're going to have speed bumps. You can do as much homework as you can and want and try to perfect everything before you launch, but things come out of left field every single day.”He’s on the show to discuss entrepreneurship, how to invest, how to build brands, how to hire the right people and what’s possible for high-functioning brains at every age.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!A New Peptide Builds Healthier Skin: https://www.oneskin.co, use code DAVE15 to get 15% offMinerals for Cell Function: https://www.beamminerals.com, use code DAVE20 to get 20% offUnlock Your Brain with Customized Nootropics:https://nootopia.com/dave, use code DAVE10 to save 10% on your first order See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

15 Juni 20221h 5min

IN THIS EPISODE OF THE HUMAN UPGRADE™...… you’ll learn how your cells, mitochondria, immune system, sleep patterns, inflammation, nerve growth pattern, and energy levels all benefit from mushrooms. These fungi are full of compounds and nutrients that your body will love. There’s a whole lot of science behind this now.In this special podcast edition, you’ll hear how two mushroom experts are studying and harnessing the amazing powers of mushrooms for the deepest parts of human biology and the natural environment. Paul Stamets, is a speaker, author, mycologist, medical researcher and entrepreneur. He’s considered an intellectual and industry leader in habitat, medicinal use and production of fungi, and he considers himself a “mycological warrior.” He’s spent over four decades in the Pacific Northwest studying and researching the world of mushrooms. Listening to him describe, decode and illuminate the workings of the mushroom world is an enthralling experience, indeed. He says we’re intertwined with mushrooms at a cellular level. He believes that habitats have immune systems—just like people—and mushrooms are cellular bridges between the two. Our close evolutionary relationship to fungi can be the basis for novel pairings in the microbiome that lead to greater sustainability and immune enhancement. And from neurogenesis to our microbiome to our mitochondria, fungi are linked to us. He’s also making some amazing discoveries having to do with bears, bees, butterflies and biodefense.Mycelium Just Might Save the Bees, And Us – Paul Stamets – #624 Learn more at fungi.com Julian Mitchell, —co-founder and CEO of the Australian-based company Life Cykel—and his team work with mushrooms as innovative food sources and medicinals in Australia. “Mushrooms and mushroom-based foods are going to play a huge role in the future of food,” Julian explains. “They grow quickly requiring very little resources in terms of water, power, and land. They have an amazing nutritional profile, and of course, they are 100% natural.” … “Mushrooms are almost an uncharted continent, with infinite applications not just in food but in biotechnology.”For day-to-day use, you’ll want to go with cooked, not raw, mushrooms. For those of you who aren’t fans of eating mushrooms, there’s an option for you, too: “Having it as a tincture makes it very easy to add to a coffee, add to a tea, add to a smoothie,” Julian says. “It’s quite tasteless and at the same time micro-dosing it in small amounts straight into your mouth is a great way to have it as well and absorb it straight into your blood system.” Mushrooms Are Your New Anti-Aging Strategy – Life Cykel #603Learn more at lifecykel.comWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Science-backed, Music-driven Breathwork: Go to https://www.othership.us/dave, sign up for the app and get two weeks free.Fitness Center of the Future: Check out franchise opportunities for biohackers at https://ownanupgradelabs.comKickstart Autophagy: https://timelinenutrition.com/DAVE, use the code ASPREY10 to get 10% off any planSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

10 Juni 202231min

IN THIS EPISODE OF THE HUMAN UPGRADE™... … you’ll learn why every breath you take makes a difference in how your entire body functions. The way you breathe affects the quality of your life and every one of your body systems. Full stop. This goes for adults and kids alike.In this special edition, breathing experts Patrick McKeown (“THE BREATHING CURE: Develop New Habits for a Healthier, Happier, and Longer Life”) and James Nestor (“Breath: The New Science of a Lost Art”) approach the topic from diverse perspectives, but agree on a lot. Especially the benefits of nose breathing and the detriment of mouth breathing.They explain the biochemical, biomechanics and psychological components of how you breathe. They also present exciting new research in pulmonology, psychology, biochemistry and human physiology that shows how making even slight adjustments to the way you inhale dramatically influences things like:sleep and snoringfitness and athletic performancebrain functionfocus and concentrationoxygen intakeheart rate and blood pressureblood sugarinternal organ functionnervous systemrespiratory healthasthma and allergiesautoimmune diseasesexfemale hormonespainstress and anxiety That's just the start of what you can change when you change your breathing. Big claims, yes. All true. And even bigger benefits for you.Breathing can nurture your body, center you, and rebalance you. When you start harnessing the power of your breath, you're going to feel incredibly better than you do right now. Patrick McKeown, an author, educator and one of the world’s leading breathing re-education experts, has researched breathing for more than two decades. Listen to more: Shut Your Mouth! Nose Breathing Improves All Your Body Systems – Patrick McKeown – #835James Nestor, a San Francisco-based science journalist, author, surfer, free diver, adventurer, and speaker, set out on a decade-long quest to find out where our breathing went wrong—and how to fix it. Listen to more: Breathing Essentials That Will Change Your Life – James Nestor – #751WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Support Your Body’s Natural Repair Mechanisms: https://eng3corp.com/DAVE/Must-Have Magnesium: https://magbreakthrough.com/DAVE, use code DAVE10 to get a 10% discountMeat Sticks! All the Good Stuff-No BS: https://paleovalley.com/DAVE, use code DAVE to get 15% off your first orderSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

8 Juni 202229min

SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: Go to https://www.oneskin.co and use code DAVE15 to get 15% off your first-time purchase.IN THIS EPISODE OF THE HUMAN UPGRADE™...…you’re listening to a new Upgrade Spotlight series based on what you told me you wanted to hear on this podcast. On one Friday each month, these shorter episodes will feature guests who’ll get right into useful information in a Q&A style. You’ll find out how to improve your energy and upgrade your performance. You’ll also get the latest knowledge about powerful tools and technologies that allow you to change your biology and the environment around you. Introducing OneSkin! During this Upgrade Spotlight, you’ll learn about new products designed to target skin aging at the molecular level and promote skin and body health. You’ll also find out the science behind OneSkin’s formulas and why they are considered “daily topical supplements.” They can help you maintain functional and resilient skin as you age. OneSkin topical supplements are powered by a proprietary peptide: OS-01, which decreases the accumulation of aged/senescent (zombie) cells in the skin. By targeting the major driver of skin aging, OS-01 has been scientifically proven to:• Repair cellular damage, including UV damage• Increase epidermal thickness• Improve barrier function• Increase the activity of genes associated with collagen, hyaluronic acid, and elastin production• Reverse the biological age of skin“So this peptide has a very interesting profile because it's small enough to penetrate and it's super safe,” explains Carolina Reis Oliveira, Ph.D., scientist, CEO and co-founder of OneSkin. “There is no toxicity, no irritation. We've done all the recommended studies by FDA for personal care products, and, has this beautiful effect of reducing the accumulation of senescent cells, and also reduces the release of inflammatory markers, and increase the production of hyaluronic acid, elastin and collagen. So, in the end, there's a molecule that has all these attributes that's very important for healthy skin, overall.”Another exciting part of this peptide work includes MolClock, the first skin-specific molecular clock, capable of reliably and accurately determining the biological age of skin. This was created by OneSkin’s team of female PhD-level longevity scientists as part of its research and development platform.Carolina relocated from Latin America to Silicon Valley in 2016 to co-found OneSkin and lead the development of the company’s disruptive skin rejuvenation technologies. She holds a Ph.D. in Immunology, along with degrees in biochemistry, stem cell biology and tissue engineering. Her team of co-founders includes three other female scientists with additional expertise in skin regeneration, bioinformatics, genomics, immunology and molecular biology. Among them, they’ve invented numerous patents and have published nearly 100 peer-reviewed papers in scientific journals.This episode explores exciting new information about improving skin health at the molecular level for the long-term. When you do that, your body will be more equipped to defend itself from environmental stressors and aggressors, especially with age. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

4 Juni 202229min

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Capture Life Force Energy: https://leelaq.com, use discount code DAVE10 to get 10% off sitewideSkin Health and Healing: https://alituranaturals.com/shop/, use code DAVE20 for 20% off storewideBusiness Growth With SEO: https://www.stephanspencer.com, get a FREE consultationSPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: Go to https://pendulumlife.com and use promo code "DAVEVIP" to get an exclusive discount.IN THIS EPISODE OF THE HUMAN UPGRADE™...…you’ll learn about emerging science that points to the effects of sugar on your gut microbiome and metabolism and the connections between sugar, your mental acuity and longevity.Biochemist and molecular biologist Colleen Cutcliffe, Ph.D., continually searches for new ways to improve your gut health and help you live longer. As CEO and co-founder of Pendulum Therapeutics, she works to turn scientific discoveries into real products that hack and heal your microbiome and its associated body systems. At Pendulum, her team identifies and isolates new bacterial strains then combines those new strains to create unique probiotics.“We really worked hard on ways to modulate post-postprandial glucose spikes through the microbiome,” Colleen says. The result? Pendulum’s Glucose Control lowers blood glucose spikes by 33 to 34% for people with type 2 diabetes. “What we didn't realize was how many people who don't have type 2 diabetes were going to end up benefiting from it.”This conversation homes in on sugar management and a broad range of research that’s exploring what you can do about managing your glucose to keep up your mental acuity (less brain fog, sharper thinking) and live a longer life. Science has discovered that as you age:You have reduced ability to metabolize sugar. Your microbiomes become less diverse and depleted of certain key strains that are important for sugar metabolism.If you improve glucose control, you see reduced neuronal inflammation and improved cognition.In the past decade, especially, sugar dominates a lot of the conversation around diet and health. It’s been studied, substituted, moderated, restricted and demonized. With that type of focus, you lose the bigger point. “You can't completely cut out sugar,” Colleen says. “You do need sugar. Not all sugar is bad for you all the time. Every cell in your body, except for your colon cells, need glucose in order to survive, in order to replicate, in order to perform functions. All of the things that allow you to be a human being require some amount of sugar."She wants you to know what’s happening to cause the change in metabolic processing as you age and what you can do about it, like:How to understand your blood glucose range and what fluctuations mean.How to track your blood glucose and what to do about peaks and dips.How to improve your focus, sharpness and mental endurance through diet and fitness.“I'm a scientist, so I'm always going to say more data is better,” Colleen explains. “[Especially] when you're trying to make improvements and you're making these micro-adjustments in your life, and you want to understand what impact are they having.”See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

3 Juni 202257min

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Hydrate with Electrolytes: https://DrinkLMNT.com/DAVE, get a free LMNT Sample Pack with 8 single-serving packets for the cost of shipping ($5 for U.S. customers) Control Blood Glucose: https://pendulumlife.com, sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipmentMattress Temperature Tech: https://www.eightsleep.com/dave, use code DAVE to save $250 on the Pod ProIN THIS EPISODE OF THE HUMAN UPGRADE™... …you’ll learn how to connect the principles of self-coaching to biohacking. You may already be doing some things, but this topic will help you fine-tune your approach in simple, yet powerful, ways.High performers typically know the value of coaches: experts who can train them and guide them toward goals. But what if you could become your own coach? Podcast guest Jason Goldsmith emphasizes the value of combining the mental and physical aspects of human performance. He knows, too, that it’s important to learn to coach yourself to achieve any kind of life success you go after. Self-coaching doesn't mean you do it all on your own, it means that you take charge of yourself, for yourself.This episode brings these concepts together so you can be in charge of yourself and be confident and purposeful when making decisions. A globally recognized performance coach and founder of Goldsmith Performance, Jason’s best known for his work with golfers, from junior, to amateur to professional skill levels. He also coaches athletes from other major sports, as well as Fortune 500 executives.He’s distilled his knowledge and partnered with David Novak, cofounder & former CEO and Chairman of Yum! Brands (owner of 45,000+ restaurants) to present sports and business coaching for high performance. They’ve created a practical guidebook for you to learn how to be your own best coach: “Take Charge Of You: How Self Coaching Can Transform Your Life and Career.”This conversation covers strategies to develop an understanding of who you are and what drives you. “That is a crucial part of choosing your SBT (single biggest thing): it should feel big, important, impactful, even aspirational,” Jason says in his book. “There is a difference between setting a goal and choosing a destination.”You can outline a process with that knowledge that sets you up for success. And then add in something you may not have considered: “Joy is a critical ingredient, and I don't think enough people have enough joy in their day-to-day life,” Jason says. “It’s really important for people to know what it is that brings them joy and what are the things that diminish their joy. So, if I was able to biohack my day, what are the things I do every single day that make me feel the best possible version of myself? But then what are the things that get in the way of that joy? And then how do I eliminate those joy blockers and have more of those joy builders?”You’ll find out how in this episode! “Take Charge of You” includes do-it-yourself lessons, stories, tips, and questions to ask yourself to track your personal growth and professional development. You can follow this blueprint for self-coaching, no matter what your goals may be.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

1 Juni 20221h 6min