#354: The DARK Side of Bodybuilding: Eating Disorders, Cellular Health & Peptide Power—How Dylan Gemelli Rebuilt Everything

In this episode, we meet Shawn Wells, the author of The Energy Formula, his new book that covers pretty much every aspect of health optimization you can think of - from nutrition to supplementation, sleep optimization to the people you surround yourself with and, most importantly, the inner work and healing we must take on to achieve truly show up as our best selves. Shawn also shares his incredible health journey, how he came to love himself on his way to a healthy lifestyle, and the many challenges he had to overcome along the way.  As a master formulator, Shawn takes us on a deep dive into choosing the right supplements that can improve health and vitality while introducing us to some little-known compounds that are sure to be game changers in metabolic health.   Meet this week’s guest: Shawn Wells MPH, LDN, RD, CISSN, FISSN is the world’s leading nutritional biochemist and expert on Health Optimization.  He has been dubbed the “World’s Great Formulator” of nutritional supplements.  Shawn is a popular speaker and has been featured on over 150 podcasts, in documentaries and on TV segments.  He has also written for numerous magazines, blogs and websites.    Key Highlights: Shawn’s personal health journey and how it shaped his career choice early on. [21:39] Shawn’s unique take on what Biohacking means to him [30:57 ] What’s in a name - breaking down the  name of Energy Formula Book [36:41 ] The After-effects of stress on our body and their different types [43:10] Resiliency in our body critical for our well being [45:29] People that are closed to you have the biggest effect on our lives and how give-and-take should manifest in every relationship [49:13 ] This is the part where we dive into the book, supplementation etc...DiHydroBerberine, L Baiba, Grains of Paradise….   Connect with  Shawn Wells: Shawn Wells Shawn Wells on Instagram   Buy the Book!!! https://www.energyformula.com

4 Mars 20211h 23min

Dr Siobhan Newman is a fellow of Dr William Seed’s SSRP (Seed’s Scientific and Research Performance) Mastermind - a growing group of physicians specializing in practicing lifestyle and regenerative medicine using, among many other things, peptides.    Dr Newman spent 20 Years as a Board-certified Emergency Room Dr. until she decided it was time to help patients actually reclaim their health and vitality. She is co-founder and Chief Medical Officer of Newman MD Lifecare in Southern California.   Our conversation covers the span of her philosophy of caring for her patients and how she integrates peptides, lifestyle management and bioidentical hormone therapy to help her patients reclaim their health and vitality. Meet this week’s guest: Dr. Siobhan Newman is board certified in Emergency Medicine and Family Medicine, specializes in Emergency Medicine. Dr Newman has also acquired advanced certifications in Bio-Identical Hormone Therapy and Peptide Therapy - the latter through the A4M. She is affiliated with Hollywood Presbyterian Medical Center and Good Samaritan Hospital and is Co-Founder and Chief Medical Officer at Newman MD LifeCare.   Key Highlights: From Emergency Room medicine to regenerative and lifestyle practice….what made it happen? Going “back to school”, learning about ways to support the body, from lifestyle to nutrition, hormones and the discovery (and study) of peptides Healing the body from the inside out The importance of symptoms over (or with testing) when assessing hormone function & balance The role of and source of toxins in inflammation and disease - addressing them through detoxification and reduced exposure Where/when do peptides fit into a protocol? Hormone replacement/optimization for people in advanced years (70’s and 80’s) (27:00) Dr Newman’s top peptides in practice… (32:00) Optimizing the immune system with peptides.. (36:00) Using peptides in cycles and in stacks….addressing cell cycles, cellular senescence, etc.   Linkage:  BPC 157 Thymus alpha 1 AOD 9604   Connect with Dr Siobhan Newman: admin@NewmanLifecare.com Linkedin NewMan MD Lifecare

1 Mars 202154min

In this episode, Part 2 of the Biostrap EVO series, we get the perspective of Biostrap’s Chief Science Officer - Kevin Longoria on the Biostrap technology, some of the clinical studies using it and how to apply some of the metrics to your health journey. Kevin and I continue the conversation about how the Biostrap EVO could be an essential tool for Biohackers looking for clinical grade data that they can trust.  We go deeper into a new metric - arterial age and elasticity and how it may turn out to be a powerful way to assess and monitor cardiovascular health.  This episode has a lot of great insights! Listen in.   Meet this week’s guest: Kevin Longoria is an expert in the field of Clinical Physiology with an emphasis on cardiopulmonary and nervous system-based approaches to optimizing health and athletic performance. His previous role is a Chief Science Officer (CSO) for a progressive neuroscience company. He is currently a Clinical Exercise Physiologist and the Chief Science Officer at Biostrap.   To buy a Biostrap:  Biostrap.com  To save 10% use promo code Longevity10   Key Highlights: 01:51 How Kevin found the Biostrap and ultimately became their Chief Science Officer  03:34 Biostrap is adapting through generations 05:46 What are the limitations of Biostrap? 07:58 What are the reading specifications of Biostrap? 08:28 Understanding Arterial Age 10:20 The ideal metrics for humans 12:14 The Biostrap data checking process 15:42 The most important metrics for people 23:52 How meditation reflects data 27:13  Wearable technology and Covid research 29:16 Covid intervention 33:42 Biometrics trigger indicators 40:51 Ideal sleeping pattern routine   Linkage:  Patrick McCown's book, The Oxygen Circadian Pattern Photoplethysmography   Connect with Kevin: Website: biostrap.com  Linkedin: https://www.linkedin.com/in/kevin-longoria-2b581b164/

26 Feb 202158min

In this episode, Elias Arjan and I talk about the new edition of the Biostrap, the BiostrapEVO. I’ve now been using Biostrap EVO for over a month and I have to say I’m pretty impressed with the quality of the data I am getting.    The BiostrapEVO along with the Shoe pod and external Heart Rate Monitor together provide one of the most advanced wearable health, activity and sleep-tracking devices on the market. The Biostrap EVO enables you to get deeper insights about your body at various points in time by providing clinical-grade data. I’m really impressed with the detailed and highly accurate data readings, exercise tracking, and recovery recommendations based on exercise, exertion, sleep quality and recovery. Another great feature of Biostrap is the heart rate monitor that provides heart rate variability, blood oxygen saturation and respiratory rate monitoring. With the upcoming release of the Heart Lab - a new feature, Biostrap EVO customers will also be able to assess and track a relatively new metric: arterial age.   Listen in to the episode and discover the powerful pros of Biostrap that health hackers find game-changing. This is the first of a two-part series - in part two I talk to Kevin Longoria, Chief Science Officer at Biostrap.   Meet this week’s guest: Elias Arjan, is the Senior Vice President at Biostrap. As part of his executive role at Biostrap, Elias oversees the marketing, communications, and sales teams and works together with the CEO to establish strategic partnerships worldwide. As a thought-leader in the field, Elias has presented at various conferences and participated in panels across medical technology and health optimization. Elias is also the Executive Director of the LA Chapter of the Biohackers Collective, a global not-for-profit dedicated to fostering community and sharing knowledge about how to unlock the code of ultimate human potential.   Key Highlights: 6:24 Elias’ background from science to the arts and athletics - the amazing path that led to his current position as SVP of Biostrap today 10:45 LA Magazine’s recent cover story on Biohacking - an interview with Elias and a number of other prominent Biohackers in LA...setting the record straight. 13:28 Eating disorders and OCD in biohacking is it really a thing? 14:01 Managing the spectrum between growth and comfort 19:12 What is a true measurement of our health? 22:00 the Biostrap difference from other devices 26:42 Importance of HRV data - and what actually is HRV? 29:49  Obsession in data health tracking 35:03 Variation Interval between heartbeats 38:31 Wearable technology after-effects 44:36 Possible reasons in sleep latency 53:42 Specifications of medical-grade wearables 59:00 Four key biometrics 01:12:26 Arterial age vs. chronological age 01:15:49 Biostrap as a pre-screening tool...   Linkage: Heart rate variability Biohackers Collective   Connect with Elias Arjan: Facebook: https://www.facebook.com/eliasarjan Website: www.biostrap.com   Linkedin: https://www.linkedin.com/in/eliasarjan Get your Biostrap EVO today! Use promo code LONGEVITY10 and save 10%

22 Feb 20211h 18min

In this episode, I got the privilege to speak with three powerful and badass women who are incredibly driven into working together to fix the gap in women's health through a masterful program they created called PowHer, designed uniquely for women, by these three talented women. We talk about how finding the right partners has made this huge task remarkably effortless, how amazing their inner synergies have come together, how each of their strengths complements the other. It's just so great to see women coming together and creating something that is not built out of any amount of competition. Just ease and beauty it's truly extraordinary. Listen to the episode.   Meet this week’s guests: Dr. Nasha Winters A global healthcare authority and best-selling author in integrative cancer care and research consulting with physicians around the world. She has educated hundreds of professionals in the clinical use of mistletoe and has created robust educational programs for both healthcare institutions and the public on incorporating vetted integrative therapies in cancer care to enhance outcomes. Dr. Nasha aims to bring integrative, bio-individual care to the women's health community and beyond.   Dasha Maximov Dasha is a yoga teacher, health coach, and founder of WhealthCo. As the Director of Health Coaching for the PowHer Program, her goal is to impart to clients and other coaches the habits that are required to make long-lasting change in health happen and to bring forth the idea that health is not reductionist, but a symphony of cascading events and things in our bodies the create an environment for disease or for health.   Kayla Osterhoff Former CDC Health Scientist, Researcher, and Health Optimization Medicine Practitioner formally trained across the spectrum of the health sciences. As the Director of Research and Development for the Women’s Health Organization, she aims to use their pilot 12-month women’s health cohort program (PowHer) as a vehicle to help bridge the gap in women’s health research and build the evidence base for high quality women-centric health care.   Key Highlights:  How Nasha, Dasha, and Kayla came into this together Why women get left out of too many clinical studies About the PowHer program How is the program different from other programs out there? Critical things included in the program How does this amazing program work Optimizing women's health like never before How do the tests work Common misconceptions in women's health Your cycle is a superpower The program is limited to 30 women in the US and Canada this March How do people learn about the program? Program limitations such as the age range, health issues, health history, etc.   Linkage: BioCurious Podcast American Board of Naturopathic Oncology World Health Organization Summit in London Whealth.co (Women's Health Community) on Mighty Networks Centers for Disease Control and Prevention Global Heart Initiative Ambien The Red Tent book   Social links: Instagram: @powherprogram | @drnashawinters | @_dashofhealth | @biocurious_kayla Website: www.powherprogram.org

16 Feb 20211h 4min

Everything You Need to Know About BPC 157 and its Practical Application in Anti-Aging, Muscle Growth and Health in General Jean-Francois Tremblay is an anti-aging expert and the owner of CanLab in Montreal, Quebec and a regular guest. In this episode, we dive deep into BPC 157, an incredibly versatile peptide that seems to have a positive effect on virtually every major system in the body.    There are a plethora of different aspects of human healing that BPC 157 can assist with - from gut healing to healing of wounds, muscle, ligament, bone and tendon repair.   It can also help to normalize blood pressure, improve brain health, ease withdrawal from alcohol and much more.   Although there is no one peptide that can do all the work on its own,  BPC 157 is one of the ones that may come the closest.   It's one of a few peptides that in certain conditions can deliver results almost before people make significant changes to anything else. At this time most of the published research on BPC 157 is still mostly animal studies but we are gradually seeing an increase in human research - we still have much to learn but in this episode, we spend some time exploring what we do know and have seen. Meet this week’s guest: Jean-François Tremblay is a frequent guest on this podcast.  He is the founder and owner of Canlab - a lab in Montreal that synthesizes high quality peptides.  Jean-Francois studied Exercise Physiology, Biochemistry, and Pharmacy at UQAM.  He has been researching (in theory and in practice) peptides and SARMS since the 90’s and has been studying the theoretical basis of what peptides are and their practical applications in sports performance, anti-aging, and health in general.  Key Highlights: 4:32 What is BPC 157? 5:57 Does BPC 157 really work? 7:18 Using BPC 157 for gastric ulcers 8:08 BPC 157's effect on growth hormone receptors 9:11 How BPC 157 supports angiogenesis 14:11 Talking about cholesterol 16:35 Applications for Crohn's disease and Ulcerative Colitis 18:09 BPC 157 for repairing ligaments 18:59 How it normalizes blood pressure, vs lowering it 24:48 Nerve regeneration 25:29 It improves alcohol intoxication 26:51 Kidney support 27:54 The stability of BPC 157 and other peptides after reconstitution 29:19 Peptides that are used in cancer research 32:46 How fast does BPC 157 break down when we ingested? 34:47 Is BPC 157 bioavailable taken sublingually? 40:33 Tricks for using  BPC 157 on an empty stomach 40:55 It resists more than we would predict with the digestive tract Connect with Jean-François Tremblay: Canlabsciences.com Promo Code: Niddam10 Disclaimer: This podcast is intended for information purposes only, none of the information is to be taken or used as medical advice.  Before making any changes to your lifestyle, supplementation or nutrition please consult with your medical provider.

5 Feb 202154min

In this episode I deep dive into the fascinating world of ketone esters with Frank Llosa one of the most passionate entrepreneurs you will meet.  By now, most of us have heard of the ketogenic diet – at its center are 3 fascinating molecules called Ketones – in this case, we are talking about beta hydroxybutyrate or BHB.  While it is often talked about as a fuel source, it turns out the BHB is so much more than that as it is also an important signalling molecule that has wide ranging benefits to the human body.  Ketone Esters are known for tasing awful and costing a small fortune but through utter dedication Frank has managed to make them palatable and more affordable in order to make this important compound accessible to more people including researchers who are still uncovering the many ways they can benefit human health.   Links https://shop.ketoneaid.com Use Promo Code Longevity to save on shipping! Frank Llosa’ s story – how he first became interested in Ketone Esters and his surprising connection to Dr Veech, a pioneer in Ketone research and science 6:35 Frank’s first pitch to Venture Capitalists on marketing Ketone Esters was not exactly a winner… 7:20 The first competitive athletes who used Ketone Esters to improve their performance and how Frank ended up providing the initial seed capital to bring Ketone Esters to the market 9:25 The journey of bringing KetoneAid to market from sending them to athletes to Indiegogo campaigns… 14:47 How much of the KE1 and the KE4 do you actually need to use in one sitting and cost? 16:51 The different sports/athletes using Ketone Esters from Triathletes to half mile runners, how and why….is it helping muscles or brain? 18:30 Talking about Ketone esters and the brain – mouse studies that show that Ketogenic Diet can heal traumatic brain injuries in mice 20:45 The brain energy gap starts at age thirty 25:22 Ketone esters for Tour de France Athletes delivered 15% faster time trials… 25:52 Ketone Esters for recovery and the importance of timing Ketone esters right during athletic competitions… 27:02 How Greg Henderson former Tour de France athlete discovered that Ketone Esters not only materially improved his performance but also affected his recovery the next day…. 29:10 How should regular people use Ketone Esters around their workouts?  No need to be Keto if you’re using it fasted (and are used to fasted workouts).  For alttitude workouts/results…. For hill workouts…. 30:37 The muscle groups that can actually use ketone esters and how this might impact how you train when using ketone esters 34:47 Ketone esters post workout for recovery and to manage excess caloric intake ….and to bring your brain online post workout. 38:02 the interplay between Ketone esters and glucose at the end of a race/event….it’s all about lasting power sometimes even at the expense of peak performance.. 39:36 Using Ketone esters for cognitive performance – a couple of real life examples … 42:57 The good news/bad news of Ketone Esters and Caffeine…augmentation and replacement 46:12 Exploring why some people may respond better or faster to ketone esters than others – ketone transporters 50:22 Franks role in getting a (30 pages!) paper written on how Ketone esters may be helpful in supporting COVID19 patients…next step….clinical trials under way as we speak!! 53:19 Setting up the first clinical trial happening in Denmark to see how ketone Esters can support the heart in patients with severe COVID19 symptoms 53:59 The link between high blood glucose levels and worse COVID19 outcomes…could a Keto diet help long haulers? 1:01 Using Ketoneaid before bedtime for sleep… 1:04 A theory on why KetoneAid might be helpful for sleep…. 1:07 How Frank occasionally uses Ketones to pre-emptively mitigate the negative impact of insufficient sleep 1:08 Ketones may help to protect from harmful effects of radiation – for people living near nuclear power plants, when flying….an unpublished mouse study on how ketones massively increased survival rate of mice exposed to deadly levels of radiation. 1:13 Ketones and weight loss – how NOT to use them… 1:14 The difference between having ketones in your blood and actually being in ketosis. 1:16 Adopting a ketogenic diet before starting to use exogenous ketones of any kind… 1:19 Do people need to be on a ketogenic diet to get benefits from ketone esters? 1:20 Using Ketone Esters to fuel the brain energy gap, to extend a fast Links: KetoneAid.com Promo Code: Longevity to save up to $20 off shipping Disclaimer:  This podcast is provided and intended for information purposes only, none of the information is to be taken or used as medical advice.  Before making any changes to your lifestyle, supplementation or nutrition please consult with your medical provider.

27 Jan 20211h 31min

Dr Nichola Conlon from Nuchido talks about why simply taking NAD is not enough to solve your NAD deficiency.  Have you ever asked yourself why NAD levels go down as we age? After all, our cells are built to recycle NAD - so why on earth is everyone so deficient?  In this episode I dig deep into the issues of NAD deficiencies due to aging or disease and, TIME+  a supplement that may just provide the missing link in restoring youthful NAD levels.   To try TIME+ for yourself: Nuchido.com  Promo Code:  Longevity10 saves you 10%   Episode Notes: 4:51 All about Nichola, she looks 22 but definitely isn’t, she has an 11 year old daughter. What she got her PHD in and more about her background. 6:40 Nutrient transport and how it actually gets transferred into the cell 9:30 How drug companies go about creating a solution. Single target approach 10:10 Biology is very complex, every pathway is connected, and expecting a drug to only affect one thing is not ideal.  11:00 The body has backup plans, the body is resilient  12:00 Why drugs have side-effects  14:00 The multi target approach and why it’s important  16:00 How aging and drug development came together 18:00 How Nuchido was born 20:24 How this supplement addresses NAD in the cell (totally unique)  21:00 Why just hoping that NAD gets to right place is not ideal 22:10 NAD is estimated to be involved in 500 different reactions in the body 23:00 When maintenance and repair pathways get turned down 24:05 The cycles of NAD that we want 25:55 How damage to the cells/aging correlate with NAD 26:15 By the time we’re 20, we’ve already lost half the NAD we’re born with, but there’s good news! 27:00 Why NAD levels naturally decline, and certain diseases decrease NAD 27:35 Chronic fatigue syndrome  27:57 The people who will notice the greatest benefits from Time+ 29:50 Lifestyle factors that affect your NAD levels 31:00 Mitochondria, lyme disease and even COVID-19 34:00 How MOST supplements boost NAD through precursors NMN and NMR 37:00 The problem with relying on precursors, and why the root cause is so important 37:57 Enzymes and NAD\ 38:20 Why in some cases taking precursors is actually worse than not taking them 39:50 Methylation and why you may need to take a methyl donor if you take precursors   40:50 The importance of NAD and NADH balance  41:30 Instead of just adding to the factory, fix the factory so that it works well 46:00 NMMT 48:00 The optimal ratio of NAD and NADH 52:00 Can NAD+ be found in nutrition?  57:30 Ingredients in Time+ and why you shouldn’t be worried if you accumulate high levels of zinc 59:20 Why green tea is so amazing, egcg and methylation  1:01:24 Why parsley is so important 1:09:00 Why whole systems are so important 1:11:40 Senescent cells and why you should pay attention to this! Disclaimer:  This podcast is intended for information purposes only and none of the information presented should ever be taken as medical advice.  Consult with your physician or medical provider before making any changes to your diet or lifestyle (including starting new supplements).

20 Jan 20211h 19min