#633: Chris Palmer, MD, of Harvard Medical School — Optimizing Brain Energy for Mental Health, The Incredible Potential of Metabolic Psychiatry, Extraordinary Case Studies, and Harnessing Mitochondria for Anxiety, Depression, OCD, PTSD, and More

#633: Chris Palmer, MD, of Harvard Medical School — Optimizing Brain Energy for Mental Health, The Incredible Potential of Metabolic Psychiatry, Extraordinary Case Studies, and Harnessing Mitochondria for Anxiety, Depression, OCD, PTSD, and More

Brought to you by Levels real-time feedback on how diet impacts your health, Athletic Greens all-in-one nutritional supplement, and LinkedIn Marketing Solutions marketing platform with 800M+ users.

Dr. Christopher M. Palmer (@chrispalmermd) is a Harvard psychiatrist and researcher working at the interface of metabolism and mental health.

Dr. Palmer is the director of the Department of Postgraduate and Continuing Education at McLean Hospital and an assistant professor of psychiatry at Harvard Medical School. For over 25 years, he has held administrative, educational, research, and clinical roles in psychiatry at Harvard. He has been pioneering the use of the medical ketogenic diet in the treatment of psychiatric disorders—conducting research in this area, treating patients, writing, and speaking around the world on this topic.

He has developed the first comprehensive theory of what causes mental illness, integrating existing theories and research into one unifying theory—the brain energy theory of mental illness. You can learn more in his new book Brain Energy: A Revolutionary Breakthrough in Understanding Mental Health—and Improving Treatment for Anxiety, Depression, OCD, PTSD, and More.

Please enjoy!

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This episode is brought to you by Athletic Greens. I get asked all the time, “If you could use only one supplement, what would it be?” My answer is usually AG1 by Athletic Greens, my all-in-one nutritional insurance. I recommended it in The 4-Hour Body in 2010 and did not get paid to do so. I do my best with nutrient-dense meals, of course, but AG further covers my bases with vitamins, minerals, and whole-food-sourced micronutrients that support gut health and the immune system.

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This episode is also brought to you by LinkedIn Marketing Solutions, the go-to tool for B2B marketers and advertisers who want to drive brand awareness, generate leads, or build long-term relationships that result in real business impact.

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This episode is also brought to you by Levels! I wrote about the health benefits of using continuous glucose monitors (CGMs) more than ten years ago in The 4-Hour Body. At the time, CGMs were primitive and hard to use. Levels has now made this technology, and the unique insights that come from it, easy and available to everyone. Levels is making glucose monitoring simple, helping you see how food affects your health through real-time feedback. I started tracking my glucose years ago to learn more about what I should and shouldn’t be eating (including quantities, time of day, etc.), based on objective data from my own, unique physiology. Keeping my blood sugar stable is critical to my daily and long-term health and performance goals. Furthermore, poor glucose control is associated with a number of chronic conditions like diabetes, Alzheimer’s disease, heart disease, and obesity. It’s important.

If you’re interested in learning more about Levels and trying a CGM yourself, go to Levels.link/Tim.

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[07:14] How a woman overcame her 53-year streak of chronic paranoid schizophrenia.

[11:16] The backstory of Brain Energy‘s dedication.

[16:31] Chris’ thoughts on DSM-5 diagnostic categories.

[21:51] Chris’ first exposure to the ketogenic diet.

[28:35] Metabolic psychiatry.

[30:33] How ketosis affects the human body (e.g., sleep, mood, weight).

[39:35] Examining the mood elevation of ketosis on a bio-cellular level.

[44:24] When ketosis can be dangerous.

[46:44] How mitochondrial dysfunction can trigger a host of ailments.

[58:07] Dietary methods for sustaining ketosis over the long term.

[1:04:54] Common ketosis mistakes.

[1:07:53] Psychiatric medications, metabolism, and controversy.

[1:15:29] Indications that a medication impairs more than improves a patient’s condition.

[1:18:06] Resources to share with doctors open to conversation about these issues.

[1:20:41] Why quitting psychiatric medication cold turkey is a bad idea.

[1:23:20] Thoughts on the efficacy of exogenous ketones.

[1:30:32] Ketogenic diet as treatment for schizophrenia.

[1:38:34] Why you need to take radical ownership of your own health advocacy.

[1:40:33] Physical exercise for optimizing mitochondrial health.

[1:44:59] A cautionary note for people using medication for off-label results.

[1:48:49] Parting thoughts.

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For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.

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Past guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, Margaret Atwood, Mark Zuckerberg, Peter Thiel, Dr. Gabor Maté, Anne Lamott, Sarah Silverman, Dr. Andrew Huberman, and many more.

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#727: In Case You Missed It: February 2024 Recap of "The Tim Ferriss Show"

#727: In Case You Missed It: February 2024 Recap of "The Tim Ferriss Show"

This episode is brought to you by 5-Bullet Friday, my very own email newsletter.Welcome to another episode of The Tim Ferriss Show, where it is my job to deconstruct world-class performers to tease ou...

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#724: Claire Hughes Johnson — How to Take Responsibility for Your Life, Create Rules That Work, Stop Being a Victim, Set Strong Boundaries, and More

Claire Hughes Johnson currently serves as a corporate officer and advisor for Stripe, a global technology company that builds economic infrastructure for the Internet. Claire previously served as Stri...

27 Feb 20242h 19min

#723: In Case You Missed It: January 2024 Recap of "The Tim Ferriss Show"

#723: In Case You Missed It: January 2024 Recap of "The Tim Ferriss Show"

This episode is brought to you by 5-Bullet Friday, my very own email newsletter.Welcome to another episode of The Tim Ferriss Show, where it is my job to deconstruct world-class performers to tease ou...

22 Feb 202448min

#722: Cal Newport — How to Embrace Slow Productivity, Build a Deep Life, Achieve Mastery, and Defend Your Time

#722: Cal Newport — How to Embrace Slow Productivity, Build a Deep Life, Achieve Mastery, and Defend Your Time

Cal Newport is a professor of computer science at Georgetown University, where he is also a founding member of the Center for Digital Ethics. His books have sold millions of copies and been translated...

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#721: Master Negotiator William Ury — Proven Strategies and Amazing Stories from Warren Buffett, Nelson Mandela, Kim Jong Un, Hugo Chávez, and More

#721: Master Negotiator William Ury — Proven Strategies and Amazing Stories from Warren Buffett, Nelson Mandela, Kim Jong Un, Hugo Chávez, and More

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#720: Life Lessons from Taylor Swift, Conquering Anxiety, Coaching Teens, Career Reinvention, Supposedly Gay Bulls, Your Shadow Side, and More — Soman Chainani

#720: Life Lessons from Taylor Swift, Conquering Anxiety, Coaching Teens, Career Reinvention, Supposedly Gay Bulls, Your Shadow Side, and More — Soman Chainani

Soman Chainani is the bestselling author of The School for Good & Evil book series, which has sold more than 4 million copies, been translated into 35 languages across six continents, and been adapted...

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