Part 35 - Dr. Thomas Seyfried on Cancer as a Metabolic Disease, More Effective Therapies, and Treating it Without Toxicity

Part 35 - Dr. Thomas Seyfried on Cancer as a Metabolic Disease, More Effective Therapies, and Treating it Without Toxicity

Dr. Thomas Seyfried is a Professor of Biology at Boston College, and received his Ph.D. in Genetics and Biochemistry from the University of Illinois. He then worked as an assistant professor in the neurology department at the Yale school of medicine. He has over 180 peer-reviewed publications and is author of the book, Cancer as a Metabolic Disease. He recently received a Lifetime Achievement Award from the Academy of Complimentary and Integrative Medicine.

I got a chance to meet and interview him at the Metabolic Health Summit earlier this year. You'll notice we did this podcast shortly after the Super Bowl. In case people aren't familiar with American football the New England Patriots had just beaten the LA Rams.

I hope people look up the paper he recently published that we mention and watch his presentation I linked to in the show notes and go deeper on this topic. It's very surprising to learn of this completely new view on cancer if you haven't heard of it before. This really shouldn't be very surprising to anyone, however, because of course our modern diet and lifestyle would have the biggest effect on the rising cancer rates. And of course fixing these things would also be a major part of the treatment. He's really doing legendary work. So without further ado, here's professor Seyfried.

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Show Notes

  • Dr. Thomas Seyfried believes cancer is a metabolic disease, not a genetic disease and explains in simple terms why that is
  • The mitochondria in your cells make energy (ATP)
  • There's 2 types of energy: ancient energy which is a fermentation metabolism which means you can make energy without oxygen, or respiration where you make energy from breathing air
  • Cancer cells ferment - therefore they don't use oxygen
  • Not all cancer cells have genetic mutations, but all cancer cells ferment
  • The mitochondrial metabolic theory says that the organelle that makes energy from respiration is defective, forcing the cell to ferment. When the cell ferments, mutations collect in the nucleus
  • This means the genetic mutations seen in cancer cells come from a downstream effect of disruption of energy metabolism
  • The cancer cell has to consume a large amount of glucose and the amino acid glutamine in order to survive on a fermentation metabolism
  • On the other hand, normal cells use oxygen and very little amounts of glucose
  • This should make sense to a lot of people because they've probably heard cancer cells need a lot of glucose and if you starve them of that they die
  • Have to re-emphasize the fact that the DNA damage comes as a downstream effect
  • Damaged mitochondria, instead of making ATP, make Reactive Oxygen Species (ROS) or oxidative stress (which causes a lot of problems in our body)
  • The oxidative stress also causes damage to the nucleus and the genome
  • The field of cancer research studies effects instead of causes
  • We're not treating cancer by looking at the root cause - it's absurd - how would we ever cure it?
  • This is supported by thousands of experiments and studies
  • Obvious step to treat cancer is to deprive the cancer cells of glucose and glutamine and transition healthy cells into the use of ketones which they can readily use
  • We evolved as a starving creature and convert fatty acids into ketones and usable forms of energy
  • Cancer cells can't use ketones
  • There's no dietary way to restrict glutamine to the cancer cells so drugs have to be used
  • Basically nobody he's heard of is treating it this way
  • If it's so clear this is how cancer works, why has this not reached the mainstream?
  • The Federal government puts out websites saying cancer is genetic, medical schools teach it's genetic, leading cancer clinics tell patients it's genetic
  • Entrenched beliefs continue this. Also funding money is all based around the genetic theory
  • If you look at the mitochondria of any cancer cell under an electron microscope you can easily see the damage to the organelles and mitochondria
  • Cancer is a result of the industrialization as a society
  • Cancer is so rare throughout history or with non-industrialized societies they don't even have the word for it in their language
  • Cancer comes from all kinds of things like pollution, chemicals, radiation, hypoxia, infections, chronic inflammation, even some rare inherited diseases like BRCA1 (but it has to damage the mitochondria)
  • These are all secondary - the root cause is damage to the respiration
  • Obese people have higher rates of cancer and also higher inflammation (measured by C reactive protein)
  • To avoid cancer it's as simple as avoiding diets and lifestyles that risk damage to the mitochondria
  • Metabolic therapies need to at least be options for people
  • Problem is doctors aren't aware of them or aren't trained on them
  • Therapeutic ketosis is a medicine - it's different than just a diet (which is a turn-off to a lot of medical professionals)
  • There's therapeutic weight loss and toxic weight loss
  • Using a suite of therapies to cure cancer including ketogenic metabolic therapy and hyperbaric oxygen therapy
  • Hyperbaric oxygen creates reactive oxygen species that kills cancer cells but healthy cells using ketones are protected from oxidative stress and are fine
  • Burning ketones creates less ROS (which is a good thing) and is why many people without cancer eat a ketogenic diet
  • ROS damages tissues and is why you age
  • He published the glucose-ketone index calculator
  • People need to realize sweets are a treat once in awhile - not an everyday thing
  • The food industry has played into our ancient desires for sweet
  • Otto Warburg studied cancer in the early 1900s
  • He found that cancer cells would grow in an 100% oxygen environment - they continue to ferment and create lactic acid
  • Because their mitochondria are defective they can't switch back to oxidative phosphorylation
  • He recently published a paper filling in the gaps from Otto Warburg's work
  • Missing link was the glutamine that cancer cells can also use
  • Have to pulse the glutamine so the immune system can do it's job and clear out the dead cells
  • He's developed the press-pulse system in his lab to attack tumors strategically
  • Almost there with dosage, timing, and schedule - when done with this will have the pathway to resolution
  • He's having trouble getting funding for this for some reason
  • One problem is people have created separate little communities and foundations around their specific type of cancer even though they all have the common metabolic foundational problem
  • People are going to have to participate in the management of their disease and the culture of the diseases has to change
  • Another problem is the high cost of these standard therapies - people have to pay $400k
  • His paper looking at research conducted on cancer https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941741/
  • If you take a normal cytoplasm and implant a nucleus with a tumor you get normal cells. But if you implant a normal nucleus to a cell with damaged cytoplasm, you get more tumor cells. This shows it's the damaged mitochondria in the cytoplasm, not the DNA in the nucleus
  • The wheelchair doesn't cause your legs to not work
  • Needle biopsies are putting people at risk and are pointless
  • He calls this general misunderstanding of cancer the biggest tragedy in the history of medicine
  • What do critics of his views say? They try to create doubt
  • They rely on private funding and some great organizations supporting this research
  • Travis Christofferson's foundation https://foundationformetaboliccancertherapies.com
  • His book Tripping Over the Truth https://www.amazon.com/Tripping-over-Truth-Overturning-Entrenched/dp/1603587292/
  • Dr. George Yu's foundation https://yufoundation.org
  • Presentation by Dr. Seyfried https://www.youtube.com/watch?v=APwnkpD_BfI&frags=pl%2Cwn
  • Dr. Seyfried's book https://www.amazon.com/Cancer-Metabolic-Disease-Management-Prevention/dp/0470584920/

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Avsnitt(235)

Part 179 - Dr. Aseem Malhotra on Was It Safe & Effective?

Part 179 - Dr. Aseem Malhotra on Was It Safe & Effective?

Dr Aseem Malhotra is an NHS Trained Consultant Cardiologist, and visiting Professor of Evidence Based Medicine, Bahiana School of Medicine and Public Health, Salvador, Brazil. He is a world renowned expert in the prevention, diagnosis and management of heart disease. He is honorary council member to the Metabolic Psychiatry Clinic at Stanford University school of medicine California, and is Cardiology MSc examiner at the University of Hertfordshire, UK. He is a founding member of Action on Sugar and was the lead campaigner highlighting the harm caused by excess sugar consumption in the United Kingdom, particularly its role in type 2 diabetes and obesity. https://doctoraseem.com/biography/ Get the free gift from LMNT DrinkLMNT.com/PeakHuman GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org SHOW NOTES: 00:30- Introduction 04:03- How Dr. Aseem's views have changed 06:15- Transition to Rumble 08:18- A framework for the rest of the discussion 13:28- the evidence-based medicine triad 15:35- how to survive the medical miss information mess 18:30- The corruption of medicine from pharmaceutical companies 19:20- Blatant misconduct from the pharmacy industries 21:15- What about the life-saving drugs? 29:00- Statistical literacy 32:25- The effects of fear and stress 34:20- The real impact of the vaccine 49:00- Dr. Aseem's consensus on the data 1:00:00- The harms of the vaccine 1:08:00- Getting to the root of the problem? 1:28:30- Where to find the best products on the market For full show notes join the Peak Human Patreon http://patreon.com/peakhuman GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

16 Dec 20221h 34min

Part 178 - Dr. Suneel Dhand on Big Pharma Bribing Your Doctor & Worldwide Corruption

Part 178 - Dr. Suneel Dhand on Big Pharma Bribing Your Doctor & Worldwide Corruption

Dr. Suneel Dhand is an internist in Hyannis, Massachusetts and is affiliated with multiple hospitals in the area, including Salem Hospital and Beth Israel Deaconess Medical Center. He received his medical degree from The University of Wales College of Medicine and has been in practice between 11-20 years. https://suneeldhand.com/ BUY THE MEAT NosetoTail.org FREE SAPIEN LIFESTYLE GUIDE Sapien.org SHOW NOTES: 00:18- Introduction to Dr. Dhand 05:00- Dr. Dhand transition out of the typical healthcare system 08:00- Your doctor wants you to be sick 10:00- How big pharma is bribing your doctor 11:30- Dr. Dhand approach to treating his patients 15:45- Using food as medicine 21:35- Why eating meat could actually be dangerous 23:15- Dr. Dhand's optimistic view of our health future 25:30- The corruption of medicine 30:40- The real Anthony Fauci 34:20- The intertwined agenda of big pharma, big tech, and mainstream media 41:30- Big pharma's flawed studies 50:50- Medical dictatorship and mass psychosis 58:45 - The effects of mainstream media 1:04:10- The fallacy of the "greater good" 1:18:55- Where to find Dr. Dhand BUY THE MEAT NosetoTail.org Support me on Patreon! http://patreon.com/peakhuman Preorder the film here: http://indiegogo.com/projects/food-lies-post Film site: http://FoodLies.org YouTube: https://www.youtube.com/c/FoodLies Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

7 Dec 20221h 24min

Part 177 - Ty Beal on the Top Nutrient Dense Food List & Global Nutrition Solutions

Part 177 - Ty Beal on the Top Nutrient Dense Food List & Global Nutrition Solutions

Ty Beal is based in Washington DC as a Research Advisor on the Knowledge Leadership team at the Global Alliance for Improved Nutrition (GAIN). In this role, he supports programmes, research, evaluation, and dissemination of knowledge to stakeholders. He has extensive experience examining sustainable food systems, diet quality, food affordability, food supplies, micronutrient deficiencies, child growth and development, noncommunicable diseases, and global health. He obtained a PhD in Geography with emphasis in Global Nutrition from the University of California, Davis, where he was a National Science Foundation Graduate Research Fellow.   GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org   SHOW NOTES: 00:00- A little bit about who Ty is 01:40- Why should we care about nutrients? 06:30- Ty's studies and the 6 most important nutrients 13:40- The importance of bioavailability and anti nutrients 20:50- Why we should stop fearing animal foods 23:00- Astonishing worldwide deficiency statistics 31:15- What even is a whole grain? 32:40- The food compass 42:15- Nutrient intake and stunted growth 47:00- Discussion on the food environment 52:50- The environmental issue and the future of health 1:00:00- The Eat Lancet diet 1:08:00- The spectrum of healthy diets 1:09:15- Should you eat leafy greens? 1:19:00- Where to find Ty   GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org   Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

30 Nov 20221h 27min

Part 176 - Decentralization Solving Many of the World's Biggest Problems w/ Matt Grebosky & Brian Sanders

Part 176 - Decentralization Solving Many of the World's Biggest Problems w/ Matt Grebosky & Brian Sanders

This is a special episode on decentralizing the main areas of society and your life to solve some of the biggest problems we're facing. The big systems are working against us. Most aspects of society are being centralized by corporations and governments at the expense of the individual. For personal health & wealth you should be decentralizing your: - Food/food production - Finances - Health(care) - Community - Education Listen for some practical solutions! Brian Sanders is the filmmaker behind the Food Lies documentary, host of the top 5 nutrition podcast Peak Human, and an international speaker. He graduated from UCLA with a degree in Mechanical Engineering. He works as a Health Coach at Evolve Healthcare and co-founded the health education company Sapien. He also works to spread the awareness of regenerative agriculture and increase access to well-raised animal products through his company Nose to Tail. Matt Grebosky is a CHEK Practitioner, Holistic Health Coach and Head of Operations at Nose to Tail and The Sapien Center. Specializing in ancestral health, nutrition and living, Matt uses a blend of modern science and traditional practices to offer advice on how to approach living a healthy and happy life. Matt studied Holistic Lifestyle and Exercise Coaching at the CHEK Institute in Vista, California after graduating from Penn State University with a degree in Kinesiology. Coaching in various different formats for several years he then transformed his passion for ancestral health to start working for Nose to Tail and eventually The Sapien Center. Follow Matt on Instagram MattGrebosky.com

15 Nov 20221h 11min

Part 175 - Chris Kresser on Why The World is Unhealthy (And What To Do About It)

Part 175 - Chris Kresser on Why The World is Unhealthy (And What To Do About It)

Chris Kresser, M.S., L.Ac., is a globally-renowned expert, clinician, and educator in the fields of Functional Medicine and ancestral health and the New York Times bestselling author of The Paleo Cure and Unconventional Medicine. He was named one of the 100 most influential people in health and fitness by Greatist.com and has appeared as a featured guest on Dr. Oz, Time, The Atlantic, NPR, Fox & Friends, and other national media outlets. ChrisKresser.com   Chris co-founded and co-directed the California Center for Functional Medicine, one of the largest Functional Medicine clinics on the west coast. Throughout his 15-year career he has helped hundreds of patients reverse chronic disease and recover their health and vitality.   GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org   SHOW NOTES   02:40 - Barriers to proper healthcare consulting 03:50 - How the modern food system is causing Nutrient deficiencies.  05:45 - Why eating healthy might not be enough to combat nutrient deficiencies 11:00 - Can we get enough nutrients in the modern environment?  14:30 - Chris's thoughts on hair mineral analysis testing.  16:45 - The problem with vegan and carnivore diets. 21:50 - Nutrient degradation overtime 25:40- Chris's opinion on oxalates and plant toxins.  28:20- The benefits of eating seasonally 34:50 - Humans have an innate drive to eat certain foods.  39:50 - The nutrient leverage hypothesis. 45:15 - Why we don't know about our nutrient deficiencies. 48:00 - The best ways to maximize the nutrient density of our diets. 57:05 - The issues with the dietary guidelines 59:15 -  Chris's opinion on phytonutrients 1:02:30 - Many diets can work to elicit good health. 1:06:30- The height studies 1:13:40 - Practical way to optimize your nutrient status.  1:22:30 - Where to find Chris Kresser   GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org   Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

9 Nov 20221h 29min

Part 174 - Leigh Erin Connealy, MD on How to Eat to Save Your Life

Part 174 - Leigh Erin Connealy, MD on How to Eat to Save Your Life

Leigh Erin Connealy, M.D. is a prominent leader in the Integrative & Functional Medicine medical field. She is the Medical Director of two amazing clinics "The Cancer Center For Healing" & "Center For New Medicine". The clinics have become the largest Integrative Medical Clinic in North America and visited by patients from all over the world with 47,000 patients and growing. She's authored 2 books including "The Cancer Revolution" and was named one of the top 50 functional & integrative doctors in the country in 2017. https://www.connealymd.com/ GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org SHOW NOTES 0:00- Welcome back Dr. Connealy! 00:06- A picture of what life at Dr. Connealy's clinic looks like 2:03 - How to screen for cancer in the healthiest way. 9:28- The variables cancer patients need to pay attention to. 11:24- A brief aside about the health of the population 12:30- Important practices that Dr.Connealy recommends 19:30 - Dr. Connealy's approach to stress management 21:55 - Why stress is such a big issue in the modern society 27:00 - The last 10 % can make a big difference 32:25- How Dr. Connealy and her team eats. 41:45 - Why proper screening is so important. 49:40- The importance of the internal terrain. GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

2 Nov 202259min

Part 173 - Dr. Leigh Erin Connealy, MD on Treating Cancer with Diet & Lifestyle

Part 173 - Dr. Leigh Erin Connealy, MD on Treating Cancer with Diet & Lifestyle

Leigh Erin Connealy, M.D. is a prominent leader in the Integrative & Functional Medicine medical field. She is the Medical Director of two amazing clinics "The Cancer Center For Healing" & "Center For New Medicine". The clinics have become the largest Integrative Medical Clinic in North America and visited by patients from all over the world with 47,000 patients and growing. She's authored 2 books including "The Cancer Revolution" and was named one of the top 50 functional & integrative doctors in the country in 2017. https://www.connealymd.com/ GET THE MEAT http://NosetoTail.org JOIN THE NEWSLETTER http://sapien.org SHOW NOTES 06:15 -How Brian found Dr. Connealy 06:53 -What Dr. Connealy does 31:45 -Why health starts at the mitochondria 41:30 -The mindset 42:10 -Find Dr. Connealy GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

26 Okt 202243min

Part 172 - Dan Kittredge on the Amazing Power of Nutrient Density and How to Measure It

Part 172 - Dan Kittredge on the Amazing Power of Nutrient Density and How to Measure It

Dan Kittredge has been an organic farmer for more than 30 years and is the founder and executive director of the Bionutrient Food Association (BFA), a non-profit whose mission is to "increase quality in the food supply." Known as one of the leading proponents of "nutrient density," Dan works to demonstrate the connections between soil health, plant health, and human health. Out of these efforts was born the Real Food Campaign, now the Bionutrient Institute, which has engineered a prototype of a hand-held consumer spectrometer designed to test nutrient density at point of purchase. Via the Bionutrient Meter, the goal is to empower consumers to choose for nutrient quality and thereby leverage economic incentives to drive full system regeneration. https://www.bionutrientinstitute.org/meetdan BUY THE MEAT NosetoTail.org Support me on Patreon! http://patreon.com/peakhuman SHOW NOTES 00:00 - Dan's upcoming events 00:45- Why should we care about nutrient density? 1:25 - Weston A. Price 1:50 - Why are some foods more nutrient dense than others? 4:08 - Dan's background. 7:02 - The Bio nutrient association. 8:00 - Your body is made up of the foods that you are eating. 9:50 - Nutrient density starts in the soil 14:40 - The modern food environment is blunting our natural instincts for nutrients. 18:40 - Dan's mission to inform the public about nutrient density 33:30 - The sick care system 36:30 - What is spectroscopy? 44:00- Dan's vision for the future 48:00 - The beef project, and how the plants are affecting the quality of the meat. BUY THE MEAT NosetoTail.org Support me on Patreon! http://patreon.com/peakhuman Preorder the film here: http://indiegogo.com/projects/food-lies-post Film site: http://FoodLies.org YouTube: https://www.youtube.com/c/FoodLies Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

19 Okt 20221h 8min

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