Biohacking News Weekly Update : 1363

Biohacking News Weekly Update : 1363

This episode covers:


• Cocoa Extract Cuts Heart Deaths

A massive COSMOS trial found that older adults taking high flavanol cocoa extract daily saw a 27 percent reduction in cardiovascular deaths along with drops in inflammation markers like HSCRP. Women showed unique anti inflammatory cytokine shifts, pointing to a broader longevity effect. Dave explains why cocoa extract is becoming a foundational nutrient for vascular health rather than a dessert ingredient.

Source: https://www.sciencedaily.com/releases/2025/09/250926135957.htm


• AI Stethoscope for Home Diagnostics

Lapsi Health’s Keikku 2.0 just became the first FDA cleared AI powered digital stethoscope for both clinicians and home users. It records heart and lung sounds, analyzes them instantly, and flags early warning signs before symptoms appear. Dave breaks down why tools like this move you from reactive to predictive medicine and why they belong in every quantified self toolkit.

Source: https://www.prnewswire.com/news-releases/lapsi-health-unveils-keikku-2-0-worlds-first-fda-cleared-digital-stethoscope-with-integrated-ai-scribe-302585083.html?utm_source=chatgpt.com


• Beef Organ Supplements Surge

Beef organ supplements have exploded more than 8,000 percent this year, driven largely by women reporting improvements in energy, hormones, mood, and skin. Liver, kidney, and heart deliver vitamin A, heme iron, B12, copper, and choline that modern diets often lack. Dave covers sourcing concerns, purity standards, and why this shift reflects a move from fear based nutrition to evolutionary nutrition.

Source: https://www.verywellhealth.com/beef-organ-supplement-11710185?utm_source=chatgpt.com


• Spirulina for Collagen and DNA Protection

New research highlights spirulina’s ability to support collagen production, reduce oxidative stress, protect DNA, and improve glucose and lipid balance. It is becoming a staple of eco focused anti aging routines and is driving the viral green stacking trend with chlorella and chlorophyll. Dave explains why spirulina functions as a clean daily defense against oxidative stress.

Source: https://www.news-medical.net/news/20250707/Is-Spirulina-the-Next-Anti-Aging-Superfood.aspx


• Health Data Privacy Reform

A new Senate bill aims to extend HIPAA level protections to wearables, genomic tools, glucose monitors, and wellness apps. The goal is to give users control over who sees their biometrics, how they are stored, and whether they can be sold. Dave outlines why this matters for anyone using Oura, Whoop, CGMs, or genetic testing and why your biology should belong to you and not the cloud.

Source: https://natlawreview.com/article/federal-healthcare-update-november-7-2025


All source links provided for easy reference to the original reporting and research above.


This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality.


Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.


New episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.


Keywords: cocoa extract, flavanols, heart health, nitric oxide pathways, COSMOS trial, AI stethoscope, digital diagnostics, Keikku device, predictive health tech, beef organ supplements, women’s hormonal health, nutrient dense foods, ancestral nutrition, spirulina benefits, collagen support, oxidative stress defense, green stacking, chlorella pairing, DNA protection, wearable privacy laws, HIPAA reform, biometric data rights, longevity news, biohacking updates


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• Upgrade Collective: https://www.ourupgradecollective.com

• Upgrade Labs: https://upgradelabs.com

• 40 Years of Zen: https://40yearsofzen.com


Timestamps:

0:00 – Intro

0:19 – Cocoa Extract & Heart Health

1:52 – AI Digital Stethoscope

3:01 – Beef Organ Supplements

4:24 – Spirulina for Longevity

5:42 – Substack Announcement

6:53 – Health Data Privacy Reform

8:23 – Weekly Upgrade Protocol

9:46 – Outro

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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#69 Clearing Up Cholesterol with Jimmy Moore

#69 Clearing Up Cholesterol with Jimmy Moore

What if everything you thought you knew about cholesterol was wrong? In this episode of Bulletproof Radio cholesterol expert Jimmy Moore about how we’re being lied to about our cholesterol health. We discuss triglycerides and lab results and reveal a wealth of information on the basics of cholesterol. You’ll learn the difference between LDL and HDL, why you don’t have to be fat to have bad heart health, and why low cholesterol is bad for baby making! And that’s just the tip of the iceberg. Enjoy! In January 2004, Jimmy Moore made a decision to get rid of the weight that was literally killing him. At 32 years of age and 410 pounds, the time had come for a radical change of lifestyle. A year later, he had shed 180 pounds, shrunk his waist by 20 inches, and dropped his shirt size from 5XL to XL. He is regarded as a fan of low carbohydrate diets and eating plans and promotes them through his blog, books, YouTube videos and podcasts. He currently resides in Spartanburg, South Carolina. Moore's latest book Cholesterol Clarity is a joint venture with Dr. Eric C. Westman. This book lays out in plain language what the numbers in a cholesterol test mean, and what can be done about them. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

25 Okt 201356min

#67 For the Love of Fermentation with Jill Ciciarelli

#67 For the Love of Fermentation with Jill Ciciarelli

Fermenting phenomenon Jill Ciciarelli is on the show to talk about her healthy hobby turned full-time passion, food fermentation. It’s a discerning topic amongst Bulletproof Radio listeners and enquiring minds want to know: Is fermenting optimal or not? You’ll hear Jill and Dave share their personal experiences with eating fermented foods, how it improves Jill’s life, and why Dave’s still a bit skeptical. Jill Ciciarelli is the author of Fermented: A Four Season Approach to Paleo Probiotic Foods and founder of the health blog First Comes Health. She graduated from the Institute for Integrative Nutrition as a holistic health coach and is certified by the American Association for Drugless Practitioners. Ciciarelli lives in Pennsylvania with her husband and a cat named Quincy. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

17 Okt 201342min

#66 “The Calorie Myth” with Jonathan Bailor

#66 “The Calorie Myth” with Jonathan Bailor

Millions of enquiring minds want to know: Calories, do they count or not? What if everything you were taught about eating, exercise, weight loss, and health could be proven wrong? On this episode you’ll hear Jonathan Bailor make a pretty sane argument for no more calorie counting and how doing so may actually be bad for your health! Learn how to eat more to weigh less, why you’ll want to ignore that number on the treadmill, and how not to be a slave to willpower. There’s a lot going on in this show! Collaborating with top scientists for over 10 years, analyzing over 1,300 studies, and garnering endorsements by top doctors from Harvard Medical School, Johns Hopkins, Yale, and UCLA, Jonathan Bailor is a nutrition and exercise expert and  former personal trainer who specializes in using high-quality food and exercise to simplify wellness. He has registered over 25 patents and authored the revolutionary upcoming book “The Calorie Myth.”   Bailor serves as a Senior Program Manager at Microsoft, hosts a popular syndicated wellness radio show, blogs on The Huffington Post, and consults for organizations around the world. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

15 Okt 201345min

#65 The Paleo Manifesto with John Durant

#65 The Paleo Manifesto with John Durant

Author of “The Paleo Manifesto” and professional caveman, John Durant, came on Bulletproof Radio to chat about primitive living in an urban jungle. In this fun and down to earth episode you’ll hear John and I talk about Paleo being a biohack and cricket-based protein! Whether you live in a cave now or just plan on retiring in one, there’s something in this show for everyone. John Durant is an author and health entrepreneur. He recently released his first book – The Paleo Manifesto: Ancient Wisdom for Lifelong Health – in which he advocates using evolutionary principles to combat the global epidemic of obesity, diabetes, and other chronic health conditions. He studied evolutionary psychology at Harvard before moving to New York City and becoming a “professional caveman”: running barefoot through Central Park, mimicking a hunter-gatherer diet, experimenting with intermittent fasting, and doing polar bear swims in the Atlantic. John has been featured in the New York Times, and interviewed on The Colbert Report and NPR Morning Edition. He keeps a freezer chest full of organ meats in the bedroom of his Manhattan apartment, and he is fully aware of how strange that is.     See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

10 Okt 201351min

#64 Grass Fed Beef from the Mountains of Idaho, with Glenn Elzinga from Alderspring Ranch

#64 Grass Fed Beef from the Mountains of Idaho, with Glenn Elzinga from Alderspring Ranch

Alderspring Ranch produces some of the best tasting and highest quality grass fed beef in North America. Glenn Elzinga, expert organic rancher and owner of Alderspring Ranch, shares what goes into creating Bulletproof approved beef and why it’. For over 20 years Glenn and Caryl Elzinga have worked hard and stayed true to the land and the cattle that roam on it. It’s a family ranch with a ton of heart and in this episode you will hear Glenn and I really geek out about beef. You will learn about the roots of Alderspring, why it’s so important not to micro-manage roaming cattle, how eating grass fed beef makes you more Bulletproof, and a lot more! Alderspring Ranch is a real place, a family ranch. Glenn and Caryl Elzinga have grown grass fed and finished beef in Idaho’s Rocky Mountains for over 20 years. It is in the wild and pristine setting of Idaho’s high Pahsimeroi Valley that they found the ideal place to raise their certified organic Angus beef.  In addition, Glenn’s background in forest ecology and Caryl’s as a PhD in plant ecology specifically equipped them to manage their landscape-level ranch comprised of over 70 square miles of high elevation wildlands- one of the largest certified organic ranches in the U.S They are experts at producing top quality cuts of beef for the discerning public. They are the opposite of a corporate outfit or a front through which to funnel odd cattle. Their passion is to grow the best beef you’ve ever had, and do it in a way that benefits all parts of an agricultural system, including the consumer, the land, the community, the cattle, and family. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

8 Okt 201358min

#63 Q&A: Heart Rate Variability, Food Sensitivities, and Charcoal

#63 Q&A: Heart Rate Variability, Food Sensitivities, and Charcoal

Being Bulletproof is about asking questions and getting answers. Take that suspicious spot on your calf, for example. Have you ever wondered what the heck it is? Have you ever questioned how marijuana can have an effect on heart rate variability? Each month, I record a special podcast to answer questions from the Bulletproof community. We pick the best questions that come from emails, Facebook, Twitter, the Bulletproof Forum, and the blog’s comment section. In this show you’ll gain access to a wealth of information that I hope will empower you on the way to living a more optimal life. Please enjoy! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

4 Okt 201353min

#62 The New “Naked Calories” & Micronutrient, with Mira and Jayson Calton

#62 The New “Naked Calories” & Micronutrient, with Mira and Jayson Calton

Forget everything you thought you knew about micronutrients! Mira and Jayson Calton are back on the show to tell you the importance of micronutrients and discuss the new and improved “Naked Science.” You will hear about the dangers of micronutrient defficiency, the ABCs of optimal supplementation, and the importance of taking a properly formulated multi-vitamin. Did you know that in order to become micronutrient sufficient you would need to eat 27,575 calories a day of the standard American diet? Pretty crazy, right? The Calton’s have certainly done their research and this is definitely a podcast you don’t want to miss! Mira and Jayson Calton are among the world's leading experts on the topics of weight management, lifestyle medicine and micronutrient deficiency. In 2005 the Caltons’ lead a 100-country, 7 continent, 6-year global expedition to explore the dietary and lifestyle habits of people around the world– which also resulted in reversing Mira's advanced osteoporosis. The Caltons are columnists for First for Women magazine and Livestrong.com, and contribute regularly to media sources such as “Fox and Friends,” “Happening Now,” Headline News, NBC, ABC, AOL Travel, Prevention, Shape and more. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

1 Okt 201355min

#61 Gluten Sensitivity, Celiacs & Bulletproofing Your Gut, with Dr. Tom O'Bryan

#61 Gluten Sensitivity, Celiacs & Bulletproofing Your Gut, with Dr. Tom O'Bryan

Have you heard? Gluten is harmful, but do you know why? Dr. Tom O’Bryan explains away dietary gluten, how it is detrimental to your health, and why it keeps you from being optimal – in a big way! He talks about his 30 years of experience in researching Celiac disease and gluten sensitivity and how you can drastically increase the quality of your life by getting rid of gluten in your diet. We also talk about the number one supplement he recommends to Bulletproof your gut, how gluten is like morphine, and if there are such a thing as “good” grains.  If you want to understand gluten in a way you never have before and learn how it affects your body, this episode   is for you! Dr. Tom O’Bryan is a nationally recognized speaker, workshop leader, healer, and researcher specializing in Celiac disease & gluten intolerance. He is a highly esteemed clinician in treating chronic disease and metabolic disorders from a Functional Medicine perspective. Dr. O’Bryan is the Sherlock Holmes for chronic disease & metabolic disorders, a triathalete, and a second-degree black belt in Aikido. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

24 Sep 201352min

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