Biohacking News Weekly Update : 1363

Biohacking News Weekly Update : 1363

This episode covers:


• Cocoa Extract Cuts Heart Deaths

A massive COSMOS trial found that older adults taking high flavanol cocoa extract daily saw a 27 percent reduction in cardiovascular deaths along with drops in inflammation markers like HSCRP. Women showed unique anti inflammatory cytokine shifts, pointing to a broader longevity effect. Dave explains why cocoa extract is becoming a foundational nutrient for vascular health rather than a dessert ingredient.

Source: https://www.sciencedaily.com/releases/2025/09/250926135957.htm


• AI Stethoscope for Home Diagnostics

Lapsi Health’s Keikku 2.0 just became the first FDA cleared AI powered digital stethoscope for both clinicians and home users. It records heart and lung sounds, analyzes them instantly, and flags early warning signs before symptoms appear. Dave breaks down why tools like this move you from reactive to predictive medicine and why they belong in every quantified self toolkit.

Source: https://www.prnewswire.com/news-releases/lapsi-health-unveils-keikku-2-0-worlds-first-fda-cleared-digital-stethoscope-with-integrated-ai-scribe-302585083.html?utm_source=chatgpt.com


• Beef Organ Supplements Surge

Beef organ supplements have exploded more than 8,000 percent this year, driven largely by women reporting improvements in energy, hormones, mood, and skin. Liver, kidney, and heart deliver vitamin A, heme iron, B12, copper, and choline that modern diets often lack. Dave covers sourcing concerns, purity standards, and why this shift reflects a move from fear based nutrition to evolutionary nutrition.

Source: https://www.verywellhealth.com/beef-organ-supplement-11710185?utm_source=chatgpt.com


• Spirulina for Collagen and DNA Protection

New research highlights spirulina’s ability to support collagen production, reduce oxidative stress, protect DNA, and improve glucose and lipid balance. It is becoming a staple of eco focused anti aging routines and is driving the viral green stacking trend with chlorella and chlorophyll. Dave explains why spirulina functions as a clean daily defense against oxidative stress.

Source: https://www.news-medical.net/news/20250707/Is-Spirulina-the-Next-Anti-Aging-Superfood.aspx


• Health Data Privacy Reform

A new Senate bill aims to extend HIPAA level protections to wearables, genomic tools, glucose monitors, and wellness apps. The goal is to give users control over who sees their biometrics, how they are stored, and whether they can be sold. Dave outlines why this matters for anyone using Oura, Whoop, CGMs, or genetic testing and why your biology should belong to you and not the cloud.

Source: https://natlawreview.com/article/federal-healthcare-update-november-7-2025


All source links provided for easy reference to the original reporting and research above.


This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality.


Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.


New episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.


Keywords: cocoa extract, flavanols, heart health, nitric oxide pathways, COSMOS trial, AI stethoscope, digital diagnostics, Keikku device, predictive health tech, beef organ supplements, women’s hormonal health, nutrient dense foods, ancestral nutrition, spirulina benefits, collagen support, oxidative stress defense, green stacking, chlorella pairing, DNA protection, wearable privacy laws, HIPAA reform, biometric data rights, longevity news, biohacking updates


Thank you to our sponsors!


Resources:

• Subscribe to my weekly newsletter: https://substack.daveasprey.com/welcome

• Danger Coffee: https://dangercoffee.com/discount/dave15

• My Daily Supplements: SuppGrade Labs (15% Off)

• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)

• Dave Asprey’s BEYOND Conference: https://beyondconference.com

• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated

• Upgrade Collective: https://www.ourupgradecollective.com

• Upgrade Labs: https://upgradelabs.com

• 40 Years of Zen: https://40yearsofzen.com


Timestamps:

0:00 – Intro

0:19 – Cocoa Extract & Heart Health

1:52 – AI Digital Stethoscope

3:01 – Beef Organ Supplements

4:24 – Spirulina for Longevity

5:42 – Substack Announcement

6:53 – Health Data Privacy Reform

8:23 – Weekly Upgrade Protocol

9:46 – Outro

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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How to Stack Cold Water, Sauna and Breathing to Accelerate Your Metabolism – Susanna Soeberg, Ph.D. : 1014

How to Stack Cold Water, Sauna and Breathing to Accelerate Your Metabolism – Susanna Soeberg, Ph.D. : 1014

IN THIS EPISODE OF THE HUMAN UPGRADE™…Susanna Soeberg, Ph.D., a Danish researcher, international scientist and expert in cold and heat therapy for health and performance, explains how you can harness the massive benefits of cold water immersion (winter swimming), sauna, breathing, and your metabolism.When it comes to biohacking, a few things rise to the top and make a pretty big difference in your body and brain. Through her research, Susanna discovered the minimum threshold of cold and heat exposure for health benefits. We get right into that on the show. She also works with functional breathing during cold environmental conditions and cold water immersion, especially winter swimming. Have you been considering this biohack for awhile? Baby steps won’t get you there—prepare to go all-in with the cold. “You could take cold showers, for sure,” Susanna says, “but it's not going to activate your parasympathetic nervous system in the same way as submerging yourself into cold water.”Earning a Ph.D. in metabolism at the University of Copenhagen set her on course to focus her expertise on ways metabolism works for and against you—and what you can do to improve your metabolic profile. She researches obesity, Type 2 diabetes and insulin management, as well as how brown and white adipose tissue (fat) function differently within the human body.In Susanna’s new book, “Winter Swimming: The Nordic Way Towards a Healthier and Happier Life,” she describes the benefits of winter swimming and cold water immersion on your physiology, mental health, and capacity for resilience.Watch this episode on YouTube!SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://www.soeberginstitute.com and use code DAVE for a special discount on Susanna Soeberg’s 3-week course, The Thermalist CureTM.Opportunity: Breath, Cold, Stress & Resilience Conference, Feb. 18, 2023. Presentations by Susanna Soeberg, James Nestor and other experts. Register here.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Capture Life Force Energy: https://leelaq.com, use discount code DAVE10 to get 10% off sitewideMust-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discount9th Annual Biohacking Conference: https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

25 Jan 20231h 1min

How Quantum Energy Raises Your Biohacking to a New Level – Philipp Samor von Holtzendorff-Fehling : 1013

How Quantum Energy Raises Your Biohacking to a New Level – Philipp Samor von Holtzendorff-Fehling : 1013

Leela Quantum Tech sponsored this episode.IN THIS EPISODE OF THE HUMAN UPGRADE™…you’ll learn why energy frequencies have such a powerful influence on human physiology. Skeptics take note: science backs this up.Philipp Samor Von Holtzendorff-Fehling introduced quantum energy on episode #809 and its benefits on body function, cellular voltage and chakra energy. He returns to the show with exciting new research that further validates the power of this energy and its frequencies on human physiology.“Energy and frequency—that’s where the real truth is.” Philipp says. “And that's where the real life also is.”Leela Quantum Tech creates blocs (Infinity, Quantum, Travel), frequency cards, H.E.A.L. capsules, and other products charged with quantum energy. The products have been through single- and double-blind, randomized studies and tests. This research has measured mental and physical energy, organ function, neutralization of radioactive particles, protection against pesticides and herbicides, and much more. Studies also explored how quantum energy affects ATP production, HRV (heart rate variability) and food allergies. You can feel and measure the effects. And dark field microscopy studies (placebo-controlled and double-blind) performed by Dr. Beverly Rubik in the U.S. and the BESA institute in Austria looked at the physical effectiveness of Leela Bloc technology.SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://leelaq.com and use code DAVE10 to get 10% off.Watch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Protein Bars with All the Good Stuff and None of the Crap: https://rowdybars.com, use code DAVE to get 10% off9th Annual Biohacking Conference: https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

20 Jan 20231h 5min

How Your Mitochondria Control Your Brain Energy – Chris Palmer, M.D. : 1012

How Your Mitochondria Control Your Brain Energy – Chris Palmer, M.D. : 1012

IN THIS EPISODE OF THE HUMAN UPGRADE™…Harvard psychiatrist, researcher and assistant professor Christopher Palmer, M.D., introduces a bold new premise about the root cause of mental illness based on decades of research.Dr. Palmer integrated existing theories and research into one unifying theory—the brain energy theory of mental illness that’s rooted in your metabolism. Through his research, he initially pioneered using a medical ketogenic diet to treat psychiatric disorders. In this conversation, you’ll learn how he went even further to uncover the connection between mental health and metabolic disorders of the brain. That connection lies in mitochondrial dysfunction or dysregulation.His new book, “Brain Energy: A Revolutionary Breakthrough in Understanding Mental Health and Improving Treatment for Anxiety, Depression, OCD, PTSD, and More,” also explains the increased risk for mental disorders in all metabolic conditions, including diabetes, heart attacks, strokes, pain disorders, obesity, Alzheimer’s disease, and epilepsy. “Once you see the big picture of metabolism and all of the things that influence metabolism, you actually can see novel ways to intervene,” Dr. Palmer says. “And you can also raise some red flags about some of our current treatments.” Watch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Mineral-rich Salt—Unrefined & Unprocessed: https://oryxdesertsalt.com, use code DAVE10 to get 10% offSleep Solutions for High Performance: https://sleepbreakthrough.com/dave, use code DAVE10 to get an extra 10% off9th Annual Biohacking Conference: https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

18 Jan 202355min

Attention Span: How It’s Getting Lost & How to Get it Back – Gloria Mark, Ph.D. : 1011

Attention Span: How It’s Getting Lost & How to Get it Back – Gloria Mark, Ph.D. : 1011

IN THIS EPISODE OF THE HUMAN UPGRADE™…you’ll meet Gloria Mark, Ph.D., who studies how digital media impacts people's lives. Her research specifically covers how attention is affected by, and has changed, with the rise of the digital age. She’s found that attention span now averages 47 seconds on a screen—and even that’s shrinking.As a Chancellor’s Professor of Informatics at the University of California-Irvine researching human-computer interaction, Gloria examines how people handle multitasking, task-switching, interruptions, and emotions. Her new book “Attention Span: A Groundbreaking Way to Restore Balance, Happiness and Productivity” looks at human technology use from a psychological perspective.“In the thousands of hours that I have studied people in the course of their daily work, I have heard a common sentiment,” Gloria says in her book. “People report that they are overworked and exhausted because they have to deal with too much information and too many messages.”This conversation gets into the science of attention, the stress it’s causing, plus real solutions for how you can regain focus with your personal technologies. You’ll learn:How to recognize the four main types of attention;What consequences of constant interruption do to your stress levels and productivity;How to achieve focus, rhythm and balance in a day filled with attention-switching; How to structure a flow state within your day; and What four things you can do to gain agency in the digital world. Watch this episode on YouTube!Shield Yourself from EMFs: https://quantumupgrade.io, use code DAVE to get a two-week free trialKnowing Labs: Test Your Own Biology: https://knowinglabs.com/dave, use code dave to save 20% off any test kit9th Annual Biohacking Conference: Come join like-minded people June 22-24 in Orlando, Florida, for three days of awesome! You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

13 Jan 20231h 2min

Change Absolutely Everything With One Hack – Robert Waldinger, M.D. : 1010

Change Absolutely Everything With One Hack – Robert Waldinger, M.D. : 1010

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll meet Robert Waldinger, M.D., who leads an extraordinary scientific study on happiness that’s still going strong after eight decades. The study set out to understand human health by what made people thrive.Since 1938, the Harvard Study of Adult Development has tracked two groups of men and their families with the goal of discovering what really makes for a good life. Along the way, thousands of questions were asked, and hundreds of measurements were taken—from brain scans to blood work. Three strong themes emerged from the study: Social connections are really good for you. Loneliness kills.It’s the quality of your close relationships that matters.Good close relationships don’t just protect your body, they protect your brain.Dr. Waldinger combined those lifelong case studies with modern psychological research in his new book, co-authored with Marc Schulz, Ph.D., “The Good Life: Lessons from the World's Longest Scientific Study of Happiness." This discussion gives you real-life tools to hack your happiness. You’ll learn things like:how relationships improve your physical, mental and emotional health. (More than you know!)how to evaluate the effect of your relationships on your well-being. (Don’t be dragged down.)what social fitness is and how to practice it. (Yes, it’s a flex.)ways to enliven and energize your relationships. (Energy totally matters.)why casual and work relationships matter more than you think. (A surprisingly big contribution.)Watch this episode on YouTube!Don’t Miss This! Dr. Waldinger’s TEDtalk about the study is one of TED’s Top 10 episodes and viewed more than 43 million times.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Energize Your Brain & Body: https://nootopia.com/davegenius, use code DAVE10 to get an extra 10% offClear Out Zombie Cells with Senolytics: https://neurohacker.com/dave, code ASPREY to get an additional 15% off9th Annual Biohacking Conference: Come join like-minded people June 22-24 in Orlando, Florida, for three days of awesome! You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life.https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

10 Jan 20231h 13min

Upgrade Spotlight: How to Fight Zombie Cells and Win Aging – Neurohacker Collective : 1009

Upgrade Spotlight: How to Fight Zombie Cells and Win Aging – Neurohacker Collective : 1009

Neurohacker Collective sponsored this episode.IN THIS "UPGRADE SPOTLIGHT" EPISODE OF THE HUMAN UPGRADE™… you’re going to learn about the zombie cells taking up valuable space in your body and how you can clear them out with senolytics.When these zombie cells accumulate (formally called senescent cells), they negatively impact how you age. You may experience symptoms like joint discomfort, low mental and physical energy, poor metabolic health, and diminished muscular response when you work out.Naturopathic physician Greg Kelly joins the show from Neurohacker Collective, where he’s director of Product Development. His expertise includes nootropics, anti-aging and regenerative medicine, weight management, sleep, and the chronobiology of performance and health.The hallmarks of aging include nine characteristics that organisms all the way up to humans share as we age, Dr. Kelly explains. One of those characteristics is senescent cells.This discussion gets into the reasons why senescence happens, the science of senolytics, exciting new research, and new product developments that help bodies naturally eliminate senescent cells. This means a better aging process for you!SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://neurohacker.com/dave and code ASPREY to get an additional 15% off. You can trial Qualia Senolytic for up to 100 days with a full 100% money-back guarantee. Watch this episode on YouTube!9th Annual Biohacking Conference: Come join like-minded people June 22-24 in Orlando, Florida, for three days of awesome! You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

7 Jan 202332min

Sync Your Body & Mind for a More Vibrant Life – Legacy Upgrade ft. Dr. Andrew Weil : 1008

Sync Your Body & Mind for a More Vibrant Life – Legacy Upgrade ft. Dr. Andrew Weil : 1008

IN THIS EPISODE OF THE HUMAN UPGRADE™... the new year starts off with a Legacy Upgrade conversation between Dave Asprey and Dr. Andrew Weil recorded live at True Food Kitchen in Phoenix, Arizona. Dr. Weil’s an internationally known pioneer and leader in integrative medicine. He’s also a Harvard-trained botanist and medical doctor recognized worldwide for his views on living a healthy lifestyle, his philosophy of healthy aging, and his critique of the future of medicine and health care. This broad discussion both hits the high points and goes deep into nutrition, aging, energy, lifestyle, and, of course, tea. Specifically, vibrant green matcha. (Or as Dave says, “It looks like green paint.”) There’s a lot of knowledge and humor shared, as well as hard-hitting truths: “One of the most toxic cultural messages here is that the value of life diminishes with aging,” Dr. Weil says.His five pillars of good health touch on foundational elements that contribute to your core vitality and life force. Eat right! Learn the principles of nutrition and apply them to your lifeGet regular physical activityLearn and practice methods to neutralize the harmful effects of stressMaintain emotional and intellectual connectivity as you go through lifeAttend to your spiritual well-beingMore about Dr. Andrew Weil: He founded the Andrew Weil Center for Integrative Medicine at the University of Arizona. He champions the use of medicinal plants and alternative medicine, as well as the reform of medical education. He’s a clinical professor of medicine and a professor of Public Health at the University of Arizona and the author of more than a dozen books on health, wellness and optimal living. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to www.matcha.com and use code Bulletproof15 to save 15% off sitewide.Watch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!A Probiotic to Ease Stress: https://www.omnibioticlife.com/DAVE, use code DAVE20 to get 20% off. 9th Annual Biohacking Conference: Come join like-minded people June 22-24 in Orlando, Florida, for three days of awesome! You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

6 Jan 202351min

How to Simplify Your Intentions and Realize Love – Humble the Poet : 1007

How to Simplify Your Intentions and Realize Love – Humble the Poet : 1007

IN THIS EPISODE OF THE HUMAN UPGRADE™… Humble The Poet joins the show to talk about a unique perspective on love. You’ll learn:what “real” love means (hint: it’s not found or earned) and how to recognize it in your life. how to shift away from a mindset of earning more, achieving more, and gaining more attention so you can clear pathways for love to enter and flourish in your lifehow to ditch restrictive “resolutions” (that fail more often than they succeed) and instead set intentions that allow you more freedom to love yourself and others.This Canadian-born rapper, spoken-word artist, poet and international bestselling author began reciting spoken word poetry in coffee shops more than a decade ago. That creative outlet turned into an adventure that crossed genres, mediums and oceans. His style stimulates audiences with ideas that challenge conventional wisdom. His first two books, “Unlearn” & “Things Nobody Can Teach Us” became international bestsellers. His newest book focuses on self love, love for others, defining love in a different way, and how to ease up on expectations that may be holding you back: “How to Be Love(d): Simple Truths for Going Easier on Yourself, Embracing Imperfection & Loving Your Way to a Better Life.” “I’m writing this because I’m desperate,” he says in the book. “Desperate to realize love, accept love, and learn how I keep f**king it up.”Watch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Comfort Options for Hot & Cold Sleepers: https://sleep.me/daveasprey, use code ASPREY for 25% off your purchaseMust-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discount. Kickstart Autophagy: https://timelinenutrition.com/DAVE, use the code ASPREY10 to get 10% off any planSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

4 Jan 20231h 2min

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