
How Neuroinflammation Disrupts Your Immune System – Gary Kaplan, D.O. : 889
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Mattress Temperature Tech: https://www.eightsleep.com/dave, use code DAVE to save $250 on the Pod ProMust-Have Magnesium: https://magbreakthrough.com/DAVE, use code DAVE10 to get a 10 percent discountProbiotic Eases Stress: https://www.omnibioticlife.com/DAVE/, use code DAVE20 to get 20% offIN THIS EPISODE OF THE HUMAN UPGRADE...… you’ll learn about neuroinflammation and its connection to the immune system from integrative medicine pioneer Gary Kaplan, D.O. The conversation gets into many topics like the immune system, infections, chronic disease and why your brain may be on fire. It’s all connected!Dr. Kaplan is a pro at alleviating chronic pain and illness in the field of integrative medicine, by combining integrative and alternative strategies. Conventional thinking about chronic pain and depression is flawed, he says, as more research shows often those symptoms are rooted in inflammation in the brain. Three major causes of inflammation include environmental factors, childhood trauma, and epigenetics and genetics.Inflamed brains, specifically, cause mental, emotional and physical pain like depression, anxiety, chronic fatigue syndrome, chronic fibromyalgia, pediatric neuropsychiatric disorders and more, he says.Dr. Kaplan’s treats patients at the Kaplan Center for Integrative Medicine he founded in 1985. He’s board-certified in Family Medicine, Pain Medicine, and Medical Acupuncture. He’s also studied and practiced Osteopathic Manipulative Medicine, Emergency Medicine, Herbal Medicine and is certified in Chelation Therapy.Virtual Conference Zeros in on Neuroinflammation Dr. Kaplan’s drawn on his interest in brain inflammation, the immune system and chronic disease to assemble experts from around the world. This group will share new developments and research about chronic illness at a virtual conference in February 2022.The conference topics will cover brain inflammation due to immune dysregulation. You’ll also hear about new breakthrough data on diagnosis and treatment of long-hauler Covid. It’s open to the public and healthcare professionals.“Symposium on Autoimmune Encephalopathy Secondary to Infectious Disease: A New Perspective on the Pathogenetic Interaction of the Immune system, Infection and Chronic Disease”Feb. 9, 10, 11, 2022Early bird pricing = $69 before Jan. 10. Regular pricing = $99 after Jan. 10Webpage: www.hopehealingknowledge.comLanding Page (with agenda & speakers)RegistrationSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
4 Jan 20221h 7min

Upgrade Your Metabolic System with the Right Foods – Dr. Robert Lustig – Best of 2021
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Vascular System Protection: https://arterosil.com/DAVE/, get 30% off and protect your blood vessels from vulnerable plaquePowerhouse Mushrooms: https://lifecykel.com/, use code ASPREY25 to save 25%Upgrade Digestive Health: https://globalhealing.com/dave, use code DAVE15 to get 15% offIN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™… … Dr. Robert Lustig’s knowledge about the metabolic system landed with listeners in a big way.He’s a New York Times bestselling author of several books about the problems caused by sugar, processed food and the health conditions of obesity. In his latest book “Metabolical: The Lure and the Lies of Processed Food, Nutrition, and Modern Medicine,” he focuses on how real food can reverse chronic disease and promote longevity. He also challenges the current healthcare paradigm and the influence of Big Food, Big Pharma, and Big Government. “I wrote Metabolical to basically explain what is healthy,” Dr. Lustig says. “And based on the empiric data, based on the science, based on the pathologies that I describe in the book that belie chronic disease, I distilled all of the information down to six words – two precepts, six words: ‘Protect the liver, feed the gut.’”These are the eight cell pathologies that underlie all chronic disease, according to Dr. Lustig:glycationoxidative stressmitochondrial dysfunctioninsulin resistancemembrane instabilityinflammationepigeneticsautophagy"[When] you look at the entire molecular mechanism of every single one of those eight subcellular pathologies, none of them have a medicine," he says. "None of them are druggable. They're all foodable." His book also documents how processed food has impacted human health, the economy, and the environment over the past 50 years. “It’s not about obesity, it never was,” Dr. Lustig says. “The key to the kingdom is that it is not about obesity, it is about metabolic dysfunction and anyone can get it, and that’s what makes it a public health crisis, because obesity is a result of the problem, not the cause.”See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
30 Dec 20211h 12min

Upgrade Your Energy with a Hormone-Gut-Immune Trifecta – Dr. Amy Shah – Best of 2021
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Nature’s Nootropic: https://trukava.com, use code DAVE15 to get 15% offStop Junk Light: https://truedark.com and use code DAVE to get 15% off glasses for adults & kidsImprove Your Home Biome: https://homebiotic.com/dave/ to get 15% offIN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™…… Dr. Amy Shah’s approach to managing energy struck a chord with listeners.Dr. Shah, a double board-certified physician, searched for a complete mental, hormonal, and inflammatory reset after she experienced a car accident and personal energy crisis.And while she uses an integrative and holistic approach to wellness in her medical practice, what she learned about energy and fatigue connected a lot of dots.Regulating the “energy trifecta,” made up of balanced hormones, a well-functioning gut, and a healthy immune system, makes all the difference. (She’s also an expert in circadian rhythm fasting.) “These three areas communicate, and they talk to the brain constantly,” says Dr. Shah, who studied and trained at Cornell, Columbia, and Harvard Universities. “And if any of those are broken, then you're going to be tired. And so things like short fasting, circadian fasting, sinking with nature and circadian rhythms, which is our internal clock and eating the right foods really can make a difference. And of course, there's this whole component of mind, body health, which we sorely miss in Western culture.” What you eat, when you eat and mind-body health rule your energy patterns and likely could be the root cause of your fatigue. She lays out solutions in her book, "I'M SO EFFING TIRED: A Proven Plan to Beat Burnout, Boost Your Energy, and Reclaim Your Life."See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
28 Dec 202159min

Kindness: The Win-Win Superpower – Jamil Zaki, Ph.D. & Leon Logothetis : 888
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Kratom for Energy, Focus & Pain Relief: https://superspeciosa.com, use code DAVE to get 20% offUpgrade Digestive Health: https://globalhealing.com/dave; use code DAVE15 to get 15% offMore Meditation in Less Time: https://40yearsofzen.comIN THIS EPISODE OF THE HUMAN UPGRADE...… the conversation centers on what kindness is, how to practice it, and why it matters. Kindness is a powerful tool – it helps people feel less alone and truly makes the world a more joyful and tolerant place. The two insightful guests you’ll hear from in this episode – Jamil Zaki, Ph.D., and Leon Logothetis – will leave you feeling lighter, more optimistic and, well, kinder!Jamil Zaki, Ph.D., uses tools from psychology and neuroscience to help you understand how empathy works. As a professor of Psychology at Stanford University and the director of the Stanford Social Neuroscience Lab, he explains how kindness is a learnable skill. You can use it in your life more often.Jamil’s kindness research includes empathy and compassion to form a triad. “Kindness is a behavior that benefits another person,” he explains. Scientists view empathy like a big umbrella term for emotional connection and then compassion as one of the components of emotional connectedness to others.You can dive into more of his research in his book, “The War for Kindness: Building Empathy in a Fractured World.”Leon Logothetis invites you to join the kindness rebellion. He’s certain you’ll find wealth in health and happiness, success in inner peace and a definite cool factor in being kind. Leon’s a motivational speaker, adventurer and philanthropist known as the “The Kindness Guy.” His travels take him all over the world looking for and spreading kindness (binge watch both seasons of “The Kindness Diaries”). He speaks to children and adults at schools and companies about the importance of being kind in the world. Empathy and compassion have a lot to do with that.Check out his latest book: “Go Be Kind-A Life-Changing Little Journal: 28½ Adventures Guaranteed to Make You Happier,” to find out how you can get in on the kindness movement.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
23 Dec 202134min

How to Build Your Emotional Agility and Resilience – Susan David, Ph.D. & Joan Rosenberg, Ph.D. : 887
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Powerhouse Mushrooms: https://lifecykel.com, use code ASPREY25 to save 25%Track Your Health: https://info.insidetracker.com/dave, sign up to get your promo code for 25% off storewideSupplement Bioavailability: https://www.quicksilverscientific.com, use code DAVE15 to save 15% on your first order IN THIS EPISODE OF BULLLETPROOF RADIO...…you’ll learn that being adaptive to change is a skill you can cultivate. One of the most sustainable ways to keep going with the flow is knowing how to build emotional awareness. These two guests give tips on managing your emotional states so you can be more resilient in all areas of your life.Expert psychologist, trainer and speaker Joan Rosenberg, Ph.D., guides yoou to achieve your highest potential by teaching you how to be in control of your own emotions. Award-winning Harvard Medical School psychologist Susan David, Ph.D., describes all the psychological skills necessary for you to thrive in uncertain times. She challenges the common attitude that you have to “fix” your difficult emotions through positive thinking. “Emotional agility is about the capacity to be with ourselves,” Susan says. “That includes our difficult thoughts and emotions and stories and past experiences in a way that's compassionate and curious and that doesn't hold us back from being the people that we most want to be.”Since you can’t get away from emotions, there’s power in knowing how to deal with them. “We've got to be able to reconnect with ourselves so that we can move forward in the world,” Susan says.Get ready to learn some foundational skills that will make you an emotional agility pro.About Joan: The author of “90 Seconds to a Life You Love: How to Master Your Difficult Feelings to Cultivate Lasting Confidence, Resilience, and Authenticity,” teaches you how to be in control of your own emotions.Joan guides you through eight unpleasant feelings she’s pinpointed: sadness, shame, helplessness, anger, vulnerability, embarrassment, disappointment and frustration. She says the best way to approach these feelings is with confrontation and empathy.“The single most important thing I can do is to recognize someone’s pain, and just in essence, hold a mirror up to it, even if it sounds like you’re saying the things that are so obvious,” Joan says. “It has a huge impact of calming someone else’s nervous system down.”About Susan: She’s the author of “Emotional Agility: Get Unstuck, Embrace Change, and Thrive in Work and Life,” based on 20 years of research of how to get through uncertainty “For people to be healthy with themselves, with the inner worlds, these are not soft skills,” Susan says. “These are the most fundamental skills that we can have as human beings.” See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
21 Dec 202138min

Mini-Episode: Cool Facts Friday #18
In this Episode of The Human Upgrade™...Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.Beer & blue cheese found in ancient fecesBlood marker detects dementia earlyTeam flow shows up as a unique brain stateTrauma-focused psychotherapy works for PTSDMDMA improves PTSD symptoms EPISODE SPONSOR: All your cells require minerals to function. Fulvic and humic complexes provide cellular nutrition to support detoxification. Go to https://www.beamminerals.com and use code DAVE20 to get 20% offLISTEN: "Follow" or "subscribe" to The Human Upgrade™ with Dave Asprey on your favorite podcast platform.REVIEW: Go to Apple Podcasts at daveasprey.com/apple and leave a (hopefully) 5-star rating and a creative review.FEEDBACK: Got a comment, idea or question for the podcast? Submit via this form!SOCIAL: Follow @thehumanupgradepodcast on Instagram and Facebook.JOIN: Learn directly from Dave Asprey alongside others in a membership group: ourupgradecollective.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
17 Dec 202110min

Erectile Dysfunction: Causes, Solutions and Why It’s Normal – Dr. Paul Thompson : 886
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Sleep Better on Natural Memory Foam: https://myessentia.com, use code DAVEVIP to get an exclusive discountControl Blood Glucose: https://pendulumlife.com, sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipmentSubscription Box for Biohackers: Each season (and limited editions, too!) discover and enjoy innovative wellness products, hand-curated by Dave Asprey, that you may not find anywhere else. https://daveaspreybox.comSPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERSVisit https://getmyphoenix.com/dave and use code DAVE100 to save $100.IN THIS EPISODE OF THE HUMAN UPGRADE™… …urologist, surgeon and age medicine specialist Dr. Paul Thompson discusses the challenges men can experience with their sexual health, energy and performance. Erectile dysfunction happens to men at all ages and is actually quite normal. Causes can be physical, and hormones play a role. Nutrition or exercise habits may be culprits. And state of mind factors in.Dr. Thompson shares his clinical expertise on how getting to the root of what’s going on with men's sexual functioning will not only improve erectile dysfunction but also support other critical areas of men’s health. The conversation looks at the pros and cons of eating meat, what your cholesterol numbers really mean, and why cardiovascular health matters at every age.Guys, listening to this, if your doctor isn't asking you for Lp-PLA2, which is an enzyme that's expressed when there's damage to your arteries, then you have a problem. If they aren't looking at C-reactive protein, you have a problem; and if they're not looking at homocysteine, you have a problem. So, you could ask your doctor for them or you could ask your doctor, “Hey, what do you know about these?”You’ll also find out why oral health is so important and why you have to pay attention to your nitric oxide production.Dr. Thompson talks about the at-home device he helped develop at Launch Medical (he’s chief medical officer there) that's pioneering a solution for erectile dysfunction. It’s based on clinical acoustic wave therapy treatment. “Acoustic wave is really simple and it works, and it has to do with the growth of blood vessels,” he explains. The Phoenix device helps men improve and/or restore their sexual functioning.Guys and women who love guys or guys who love guys, this thing is real technology. It does work, it is not too good to be true, and it's worth talking about.This conversation takes any embarrassment or shame out of the ED equation and gets into the details of plaque, blood flow and how you can find a fix and reclaim your sexual health.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
16 Dec 20211h 25min

The Stress-Sleep Connection That’s Keeping You Up at Night – Dr. Dave Rabin : 885
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!High-Performance Leadership: https://www.humanpotentialinstitute.com/coach-training/Track Your Health: https://info.insidetracker.com/dave, sign up to get your promo code for 25% off storewideSupplement Bioavailability: https://www.quicksilverscientific.com, use code DAVE15 to save 15% on your first order SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERSVisit https://apolloneuro.com/DAVE10 to get 10% off an Apollo Neuro device.IN THIS EPISODE OF THE HUMAN UPGRADE™…...you'll learn about the impact of chronic stress in humans, how it wrecks your sleep and what you can do about it.For more than a decade, neuroscientist, board-certified psychiatrist, health tech entrepreneur and inventor David Rabin (an M.D. and Ph.D.) has been immersed in the science of stress. He’s been researching causes and ways to manage it. He’s also been helping people deal with the consequences of both acute and chronic stress.He’s back on the show (don’t miss episodes #729 and #730) to talk about how stress disturbs systems of your body and mind, which, of course, affects your sleep.Stress is not inherently bad because we require it to grow, Dr. Rabin says. “We require the stress to help us learn how to overcome the challenges that are signaled by the stress to become better, stronger, fuller versions of ourselves.” … “There are the situations where we start to see acute stress that can be healthy and very helpful to growth turn into chronic stress,” he continues. “And that chronic stress increases inflammation on a daily basis. It’s that chronic stress that increases likelihood of disease.”Dr. Rabin co-founded Apollo Neuroscience, a company that developed the first scientifically validated wearable technology that actively improves energy, focus and relaxation. This tech uses a novel touch therapy that signals safety to the brain. In new studies, it’s had a terrific impact on stress and sleep.“Health means the restoration and maintenance of balance for all of us,” Dr. Rabin says. “Critically important is managing our sleep and our circadian rhythms, and our sleep and wake cycles. Maintaining sleep and making sure we do things to have a healthy sleep rhythm is going to maximize our performance and energy availability during the day and psychedelic medicines and wearables can play as important to role in that for us as the day-to-day practices of breathwork and meditation, yoga, exercise and nutrition.”See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
15 Dec 20211h 10min






















