
Tracking planes; Peer review; Mega-virus; Astronaut
Are black boxes outdated technology? With GPS widely available in everyday gadgets like mobile phones, how could Malaysia Airlines Flight MH370 just disappear? Adam Rutherford speaks to Dr Matt Greaves, a Lecturer in Accident Investigation at Cranfield University, about how we track aircraft.Earlier this year, a new study from Japan announced a curiously easy way to make stem cells, by placing them in a mild acid bath. It seemed too good to be true, and according to recent critics, it is. One of the authors has declared that the paper should be withdrawn, that he has 'lost faith in it'.Ivan Oransky runs the site RetractionWatch, dedicated to scrutinizing irregular research. He talks to Adam about the value of post-publication peer review, and public scrutiny of science on the internet.A 30,000 year old killer, buried 100 feet under the Siberian permafrost, has risen from the dead. It's a mega virus, with the largest genome of any known virus, and, happily, only infects amoebae. Virologist Professor Jonathan Ball, of the University of Nottingham, explains the implications of reanimating dead viruses.And actual spaceman, retired NASA pilot Captain Jon McBride, came into the studio to share his out-of-this-world memories and prediction that the next generation of astronauts will be chosen on brains not brawn.Producer: Fiona Roberts.
13 Mars 201428min

LG - Chemical weapons, Turtles, Tech for wildlife, Climate
Chemical weapons Disposing of Syria's chemical weapons is a difficult task, both politically and technically. The Organisation for the Prohibition of Chemical Weapons (OPCW), responsible for the decommissioning, has kitted out a special ship, the MV Cape Ray to hydrolyse "priority" toxic substances. Hamish de Bretton Gordon, a chemical weapons expert from SecureBio, explains why destroying chemical precursors on dry land is not an option and whether the job will be done on time.Tracking turtles Satellite tags have finally given researchers insight into the "lost years" of loggerhead turtles. After many failed attempts, researchers have worked out how to attach the tiny tags to the months-old animals during the uncertain period when they leave US coastal waters and head out into the Atlantic Ocean. The data suggests the loggerheads can spend some time living in amongst floating mats of Sargassum seaweed, in the Sargasso Sea.Technology for Nature The tools and gadgets available to remotely track animals and monitor populations and their habitats are getting better and more mechanised. Cameras mounted on birds can record where they fly; audio recordings capture bat calls; satellite images monitoring habitat change. However all this digital data needs to be analysed. Professor Kate Jones, an expert on biodiversity at University College London, thinks that this is where more technological advances are needed. She wants image recognition programmes to scan through millions of remote camera images, or sound recognition of hundreds of thousands of bat calls to be developed.Climate The recent extreme rainfall has left many asking, is this weather linked to climate change? A new project 'weather@home' 2014, aims to use a large citizen science experiment to answer this question. Myles Allen, Professor of Geosystems Science at the School of Geography and the Environment, and Dr Nathalie Schaller, both of Oxford University, explain that they aim to run two sets of weather simulations. One will represent conditions and "possible weather" in the winter 2014, and the second will represent the weather in a "world that might have been" if human behaviour had not changed the composition of the atmosphere through greenhouse gas emissions. By comparing the numbers of extreme rainfall events in the two ensembles, 'Weather@Home' will work out if the risk of a wet winter has increased, decreased or been unaffected by human influence on climate.Producer: Fiona Roberts.
6 Mars 201428min

Brain Machine Interfaces; Question on Gay Genes; Studying Drinking Behaviour
Neuroscientist Miguel Nicolelis is one of the world's leading researchers into using the mind to control machines. He is involved in the "Walk Again Project" which aims to build a suit that a paraplegic person can wear and control so that he or she can kick a football at the opening ceremony of the 2014 World Cup in Brazil. Adam is joined by biomedical engineer, Professor Christopher James from Warwick University, who puts the field of Brain Machine Interfaces in context.Work published last week by Professor Ziv Williams looks at the possibility of rewiring the body. Paralysis is normally confined to spinal cord damage, not the limbs themselves. Ziv Williams' work aims to use implanted chips to bypass the injury and have the individual control their own paralysed arms.Listeners ask if there is a gene for fundamentalist intolerance. We put the question to Professor Tim Spector, author of Identically Different.Adam Rutherford heads down to the psychology department at London's South Bank University... for a pint. Dr Tony Moss has built a fake pub, complete with lighting, music and even a fruit machine, to make drinkers feel that they are in a real bar. He says the venue treads a middle ground between a sterile lab, and an actual pub, where there are too many variables to reliably study behaviour.Professor John Shepherd from Cardiff studies alcohol and behaviour from the other end - the drunken nights out that end up in A&E. A few simple initiatives have helped reduce violence levels by 40%Producer: Fiona Roberts.
27 Feb 201427min

Bees; Whales; Pain; Gay genes
Bees - Nearly all bees in the UK suffering serious declines. They're mostly threatened by habitat and land-use change. But disease also plays a part. Adam Rutherford talks to Professor Mark Brown about new work he's done looking at the evidence of diseases harboured by honeybees, spilling over into wild bumblebees.Pain and epigenetics - Marnie Chesterton goes to Kings College, London to watch identical twins being tested for pain tolerance. The study is to gain insight into the genetic components of pain perception. One area which is fascinating researchers like Professor Tim Spector is the role of epigenetics in how we process pain. Our epigenome is a system that changes the way our DNA is interpreted. Genes can be dialled up or down, like a dimmer switch, by adding little chemical tags to the DNA. These chemical tags, unlike DNA, are changeable, in response to the changing environment. So could the way we live affect the pain we feel?Whales from Space - More listeners' questions, this time, asking whether surveys using images from satellites to see whales underwater, could be hijacked by whale hunters? Peter Fretwell from the British Antarctic Survey has the answer.Genetics of sexual preference - The media is all of a twitter this week over unpublished work recently revealed on research looking for genes related to homosexuality. We hear from Professor Tim Spector on the topic, and Adam talks to Professor Steve Jones about the science.Producer: Fiona Roberts.
20 Feb 201427min

Whales from space; Flood emails; SUYI JET Lasers; CERN's new tunnel; Discoveries exhibition
Whales from Space. Scientists have demonstrated how new satellite technology can be used to count whales, and ultimately estimate their population size. Using Very High Resolution (VHR) satellite imagery, alongside image processing software, they were able to automatically detect and count whales breeding in part of the Golfo Nuevo, Peninsula Valdes in Argentina.The new method could revolutionise how whale population size is estimated. Marine mammals are extremely difficult to count on a large scale and traditional methods are costly, inaccurate and dangerous; several whales researchers have died in light aircraft accidents. How long will the floods last? Is this a trend caused by climate change? Should I turn on the kitchen taps so that house is at least flooded with clean water? We put listeners' flood questions to experts from the Centre of Ecology and Hydrology and the British Geological Survey.The instrument we're shown this week is from JET (Joint European Torus) in Culham,. It's the world's largest 'tokamak' - a type of nuclear fusion reactor. The hope is that in a few decades it could be supplying much of the world's electricity. It works by fusing nuclei of hydrogen together to produce helium and a lot of excess energy. It's the power source of the Universe, as all stars run on fusion energy. But on Earth we have to go to much more extreme conditions to achieve it. Upwards of 100 million degrees Celsius, which is around ten times hotter than the Sun. Joanne Flannagan, shows us her lasers which measure the hot fusion plasma inside JET.CERN wants a new tunnel. The 27km long, Large Hadron Collider in Geneva found evidence of the Higgs boson recently. But if we want to know more about this elusive particle and others that make up our universe, the physicists say they're going to have to go bigger. With a 100km long tunnel, in fact. Talks are afoot as to where and how they will build it. But Lucie asks reporter Roland Pease whether it'll be worth it?The current Discoveries exhibition at Two Temple Place, on the banks of the Thames, brings together treasures from eight University of Cambridge museums, in a beautiful period building, built by Waldorf Astor. The show combines objects from science and arts collections to explore the theme of 'Discoveries'. Curator Professor Nick Thomas gives Lucie Green a tour.Producer: Fiona Roberts.
13 Feb 201428min

Engineering for floods; Neanderthal genes; Switching senses; Genes in Space game
The warning that floods are likely to become more common, or more severe, won't be a high priority for those with homes currently deluged. But it is something architects, engineers and planners have been taking very seriously. Dr. Adam Rutherford finds out about some of the innovations, both in UK and abroad, being designed for homes in areas prone to flooding - from simple door guards and waterproofing which can be retrofitted to existing houses - to entire city re-landscaping, or 'waterscaping' which aims to make room for the river, rather than fighting against it.Last week Adam talked about research showing that most people of European or East Asian descent carry a small percentage of Neanderthal DNA - about 2%. He examined some of the physical characteristics we may have got from the genes of our ancient cousins. This week Inside Science addresses some of the questions this fascinating work prompted.A new study in the journal Neuron this week, looks at what happens in the brain when one of the senses is dulled. Dr. Patrick Kanold, from the University of Maryland in the States, and his colleagues simulated blindness in mice by keeping them in the dark for a week, to see what happened to the parts of their brains involved in hearing. The found that the mouse's hearing improved. We sometimes talk about the brain being 'hardwired': all the neurons locked in place from early childhood. It was assumed that there was only a short, finite period when the brain was still capable of changing, but the new research shows parts of the brain still has room to manoeuvre.A recurring problem in science is that we are far better at collecting vast amounts of scientific data than we are at actually analysing them. To combat this problem, the charity Cancer Research UK have just launched a mobile phone game, 'Genes In Space', that farms statistical analysis out to the masses. Under the guise of flying a spaceship through a meteor storm, game players actually navigate their way through genetic sequence data from breast cancer patients. The information on the virtual path they take is automatically uploaded to the database and fed back into the scientific process.Producer: Fiona Roberts.
6 Feb 201428min

Neanderthals; Plague; Wind Tunnel; Music Timing; Stem Cells
We now know that Neanderthals and our ancestors interbred over 40,000 years ago. Recent research has shown that most people of European or East Asian descent carry a small percentage of Neanderthal DNA - about 2%. But two new papers this week examine some of the physical characteristics we may have got from the genes of our ancient cousins. They include some disease susceptibilities and hair and skin characteristics, which may have helped our forebears survive in northern climes.There have been many sensationalist headlines in the news this week suggesting that the deadly bubonic plague could return, when really, it never went away. And while it can still be deadly, it can be treated early with antibiotics. In the Middle Ages the Black Death is thought to have killed up to half of the European population and so too did the Justinian Plague 800 years earlier. Now scientists have compared these two plague genomes to find that they were both caused by distinct strains of the same bacterium, Yersinia Pestis. Knowing how the pathogen evolved in the past is crucial to our understanding of possible future strains of plague. Lead author Dr David Wagner from the University of Arizona tells Dr Adam Rutherford that it's very unlikely the plague will return on a mass scale.It's a windy Show Us Your Instrument this week - Prof Konstantinos ('Kostas') Kontis, Professor of Aerospace Engineering shows us around his wind tunnel. It's used to help develop more effective plane wings, helicopter rotors, and wind turbine blades, but cyclist Sir Chris Hoy has also been a test sample. Glasgow University is currently building a hypersonic wind tunnel, which can test air flow at speeds of up to Mach 10.We all unconsciously synchronise our movements and researchers at the University of Birmingham have shown how professional musicians make tiny adjustments in their playing to keep time with their colleagues. Alan Wing, Professor of Human Movement in Psychology tells Adam how this research about minute synchronisation is helping to inform how robots can be designed to interact with humans.Stem cells can become any other cell in the body from nerve to bone to skin, and they are touted as the future of medicine. Embryos are one, often ethically charged, source of stem cells and in 2006 Nobel prize winning research showed that skin cells could be "genetically reprogrammed" to become stem cells. These were called induced pluripotent stem cells. Scientists in Japan have now shown, in mice, that this previous painstaking method of making the versatile cells can be replaced by little more than a short dip in acid. Professor Chris Mason from University College London tells Adam that this major breakthrough could be faster, cheaper and possibly safer than other cell reprogramming technologies.Producer: Fiona Hill.
30 Jan 201428min

Higgs Boson; Neutrinos; Antarctic echo locator; Rainforest fungi; Alabama rot
The Higgs boson has been discovered, providing the final piece of the jigsaw puzzle for the Standard Model of particle physics, a description of how the universe works. But what physicists haven't found yet, which they should have, are supersymmetry or SUSY particles. Roland Pease attended a recent meeting of top physicists, and shares with Adam Rutherford the latest discussions about where to look next.The history of neutrinos is littered with interesting characters. It was Wolfgang Pauli who first suggested their existence. Pauli was so unsettled by his proposal that he bet a case of champagne against anyone being able to discover these "pathologically shy" particles. Since then, scientists have built ever more elaborate experiments to try and detect these particles. Ray Jayawardhana, Professor of Astrophysics and author of a new book "The Neutrino Hunters" explains more about the most abundant particle in the universe.This week's Show Us Your Instrument is a tool used to help scientists measure the glaciers in the Antarctic. Julian Dowdeswell, a glaciologist from the University of Cambridge, uses an echo-locator to look at the dynamics of large ice masses and their response to climate change.Fungi, not viewed favourably by gardeners, can be good for rainforest biodiversity. Dr Owen Lewis from Oxford University tells Melissa Hogenboom that plots sprayed with fungicide soon become dominated by a few species at the expense of many others, leading to a marked drop in diversity.A mysterious illness killing dogs has been in the headlines this week. David Walker a veterinary specialist, says that although it's not clear what's causing the disease, people should not panic.
23 Jan 201428min