The a16z Show
The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

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The Shift in Global Drug Development

The Shift in Global Drug Development

Theo Jaffee and Gabriel Dickinson speak with Cremieux about China’s rapid rise to the top of global clinical trial output. They discuss the regulatory reforms that accelerated China’s progress, the su...

29 Apr 57min

John and Patrick Collison on Stripe's Growth, Agent Commerce, and the Future of Software

John and Patrick Collison on Stripe's Growth, Agent Commerce, and the Future of Software

This interview with Stripe cofounders John and Patrick Collison originally aired on TBPN. They discuss Stripe's 34% growth and new employee tender offer, how agent commerce and stablecoins may require...

28 Apr 20min

Ben Horowitz on Venture Capital and AI

Ben Horowitz on Venture Capital and AI

Anjney Midha, founder of AMP PBC, speaks with Ben Horowitz, cofounder of a16z, about how venture capital changed from a small, relationship-driven business into a scalable system for backing new techn...

27 Apr 1h 9min

AI Inside the Enterprise

AI Inside the Enterprise

Steven Sinofsky, board partner at a16z, Aaron Levie, CEO of Box, and Martin Casado, general partner at a16z, discuss the reality of AI inside enterprises. They cover the gap between Silicon Valley and...

24 Apr 1h

Martin Shkreli on AI, Pharma, and What Actually Matters

Martin Shkreli on AI, Pharma, and What Actually Matters

Erik Torenberg speaks with Martin Shkreli, American investor and businessman, about how he sees the AI landscape, from OpenAI to Anthropic, and what actually matters beyond the hype. They also talk th...

23 Apr 48min

Balaji Srinivasan: Prove Correct, Not Just Go Direct

Balaji Srinivasan: Prove Correct, Not Just Go Direct

Erik Torenberg and Theo Jaffee speak with Balaji Srinivasan, angel investor, entrepreneur, and author of The Network State, about how AI is transforming media, eroding trust, and reshaping how informa...

22 Apr 2h 1min

Marc Andreessen: Monitoring the Situation and the Future of Media

Marc Andreessen: Monitoring the Situation and the Future of Media

Erik Torenberg and Theo Jaffee speak with Marc Andreessen, cofounder and general partner at a16z, about the launch of Monitoring the Situation (MTS), a new, always-on media network on X. They discuss ...

21 Apr 1h 7min

Rethinking Git for the Age of Coding Agents with GitHub Cofounder Scott Chacon

Rethinking Git for the Age of Coding Agents with GitHub Cofounder Scott Chacon

Matt Bornstein speaks with Scott Chacon, cofounder of GitHub and CEO of GitButler, about why Git's user interface has barely changed since 2005, how GitButler is rethinking version control for both hu...

20 Apr 47min

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