Office Hours: Cholesterol and Heart Disease — What I’ve Changed My Mind About

Office Hours: Cholesterol and Heart Disease — What I’ve Changed My Mind About

For decades, we’ve been told that high cholesterol is the main driver of heart disease—and that lowering LDL should be the primary goal. But as science has evolved, so has my thinking. In today’s Office Hours, I explain why cholesterol alone doesn’t tell the full story, what most doctors still aren’t testing, and what’s really driving heart disease for the majority of people. Today we discuss: • Why many people have heart attacks despite “normal” LDL cholesterol • The difference between cholesterol levels and cholesterol particles • How inflammation and insulin resistance fuel heart disease • Why sugar and refined starches are more dangerous than fat • The most important labs to assess real cardiovascular risk • What ApoB, lipoprotein(a), and triglyceride-to-HDL ratio reveal about your health • How metabolic dysfunction—not cholesterol alone—drives plaque buildup Heart disease is far more complex than a single lab value. When you understand the role of metabolic health, inflammation, and the right biomarkers, you can take meaningful steps to protect your heart and long-term health. Visit ⁠functionhealth.com⁠ for 160+ lab tests at just $365 a year. Helpful Resources: Join the 10-Day Detox to Reset Your Metabolic Health https://drhyman.com/pages/10-day-detox Have a question you’d love answered on Office Hours? Submit it here 👉https://docs.google.com/forms/d/e/1FAIpQLSdNF2y4lFWEOMLlzVNlFDpJ4xl7oOpH9NlImMoHr5mHggL_Ww/viewform?usp=header

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Is HRT Safe? 10 Questions Women Ask Most — Answered by a Functional MD

Is HRT Safe? 10 Questions Women Ask Most — Answered by a Functional MD

Hormone replacement therapy is one of the most talked about—and misunderstood—topics in women’s health. For years, women were told HRT was dangerous. Now, the conversation is shifting, but many are st...

25 Touko 46min

The Latest Science on Microplastics — And What They’re Doing to Your Body | Dr. Shanna Swan

The Latest Science on Microplastics — And What They’re Doing to Your Body | Dr. Shanna Swan

We’re surrounded by plastics and environmental chemicals every day, but only recently have scientists begun to understand how deeply they may be affecting human health. On this episode of The Dr. Hym...

20 Touko 1h 12min

Are You Secretly Dehydrated? Why a 1% Drop Kills Your Focus and Mood

Are You Secretly Dehydrated? Why a 1% Drop Kills Your Focus and Mood

Hydration affects far more than thirst. Even mild dehydration can impact your focus, memory, mood, energy, and overall brain performance—yet most people walk through the day without realizing they’re ...

18 Touko 18min

Women Are Not Small Men! Why Fitness Advice Is Failing Half the Population | Dr. Stacy Sims

Women Are Not Small Men! Why Fitness Advice Is Failing Half the Population | Dr. Stacy Sims

Most health and fitness advice for women is based on research done in men. That’s something we need to rethink. On this episode of The Dr. Hyman Show, I sit down with Dr. Stacy Sims, an exercise phys...

13 Touko 1h 23min

The 5 Root Causes of Autoimmune Disease (And How to Start Healing)

The 5 Root Causes of Autoimmune Disease (And How to Start Healing)

Autoimmune disease is often treated as something random, lifelong, and out of your control. But what if it’s not your body malfunctioning—what if it’s your immune system responding exactly the way it’...

11 Touko 27min

The Real Reason You Age (And How to Slow It Down) | Dr. Eric Verdin

The Real Reason You Age (And How to Slow It Down) | Dr. Eric Verdin

We tend to think of heart disease, cancer, and Alzheimer’s as separate problems. But what if they all stem from the same underlying process? On this episode of The Dr. Hyman Show, I sit down with Dr....

6 Touko 1h 12min

6 Root Causes of Migraines (And How to Fix Them)

6 Root Causes of Migraines (And How to Fix Them)

Migraines aren’t just headaches and if you’ve ever had one, you know how debilitating they can be. But they’re not random, and they’re not just genetic. Migraines are a signal that something deeper is...

4 Touko 26min

The Mental Health Crisis Starts in the Gut | Dr. William Li & Dr. Mark Hyman

The Mental Health Crisis Starts in the Gut | Dr. William Li & Dr. Mark Hyman

It’s easy to think of mental health as something happening only in the brain. But more and more, we’re seeing how closely it’s tied to what’s going on in the gut. Today, I’m joined again by Dr. Willi...

29 Huhti 1h 5min

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