Pathophysiology of Obesity, Part 8 — Why Your Body Defends Fat Mass

Pathophysiology of Obesity, Part 8 — Why Your Body Defends Fat Mass

Why is losing weight so hard and keeping it off nearly impossible? The answer lies in how our brain and gut are wired to protect fat mass, just like they protect red blood cells, bone, or muscle mass.

Every nutrient we consume has receptors in the gut that signal to the brain, telling it how to regulate energy production, storage, and use. When you go on a calorie-restricted diet, your body interprets this as a threat. In response, your brain revs up hunger, lowers energy expenditure, and tries to restore the fat mass.
A landmark study in the New England Journal of Medicine showed that even weeks after weight loss, hunger hormones remained elevated and the drive to eat stayed high. This explains why most people regain weight after dieting. The body's biology pushes them back to their set point, the fat mass the body wants to defend.


The bottom line: calorie restriction alone rarely works long term because the body fights back. The real challenge isn't just losing weight, it's regulating the biology of energy balance so the body no longer fights to restore fat. Next episode: yo-yo dieting and the biology of weight cycling.

🌐 Learn more at weightandmetabolism.com

Tämä jakso on lisätty Podme-palveluun avoimen RSS-syötteen kautta eikä se ole Podmen omaa tuotantoa. Siksi jakso saattaa sisältää mainontaa.

Jaksot(31)

The Neuroscience of Habit — How Patterns Form, Why They Stick, and What It Actually Takes to Change Them

The Neuroscience of Habit — How Patterns Form, Why They Stick, and What It Actually Takes to Change Them

You didn't decide to reach for your phone the moment you woke up. You didn't choose to pour that second cup of coffee on autopilot, take the same route to work, or find yourself halfway through a bag ...

22 Kesä 7min

Hedonic Pleasure — Why More Never Feels Like Enough

Hedonic Pleasure — Why More Never Feels Like Enough

You finally get the thing you wanted. The meal, the moment, the reward you've been looking forward to all week. And for a brief, beautiful window — it's everything. And then it isn't. And then you wan...

15 Kesä 6min

The Pleasure Triad — How You Were Wired to Seek Comfort, Conserve Energy, and Avoid Pain

The Pleasure Triad — How You Were Wired to Seek Comfort, Conserve Energy, and Avoid Pain

You are not broken. You are not lazy. You are not lacking discipline. You are, in fact, doing exactly what a hundred thousand years of human evolution designed you to do.In Part 4 of this series, Dr. ...

8 Kesä 6min

Unhealthy Coping Mechanisms or Numbing

Unhealthy Coping Mechanisms or Numbing

If you've ever reached for food when you weren't hungry, poured a drink to take the edge off, scrolled until midnight to avoid your own thoughts, socialized mindlessly, filling your time with plans th...

1 Kesä 6min

Trauma and ACE

Trauma and ACE

Trauma doesn't just live in memory. It lives in the body — in a nervous system that never got the signal that it was safe to stand down. You may have come to Dr. Deepti Sharma looking for answers abou...

25 Touko 9min

ACE - Adverse Childhood Experiences and their impact on our health

ACE - Adverse Childhood Experiences and their impact on our health

In this foundational episode, Dr. Sharma — triple board-certified physician, certified Menopause Practitioner, and certified life coach — unpacks adverse childhood experiences from the ground up. What...

18 Touko 4min

Contributing Factors to Obesity — Genetics, Epigenetics, Hormones, and Set Point Theory

Contributing Factors to Obesity — Genetics, Epigenetics, Hormones, and Set Point Theory

In the next few episodes, I want to talk about the contributing factors or causes of obesity in detail. The number one thing is genetics. Genetic predisposition plays a foundational role, influencing ...

11 Touko 12min

How Your Weight Impacts Your Health

How Your Weight Impacts Your Health

Let's talk about what obesity actually does to your body — not to shame or scare you, but so you understand what's really at stake.In this episode, I walk through the hard science: obesity is an indep...

8 Touko 4min

Suosittua kategoriassa Terveys ja hyvinvointi

unicast
tiedenaiset-podcast
vakeva-elama-viisaampi-mieli-vahvempi-keho
psykopodiaa-podcast
terapiassa
meditaatiot-suomeksi
rss-pt-paahtio
rss-pitaisko-erota
rss-seksicast
fitnessvastaanotto
voi-hyvin-meditaatiot-2
rss-uplevel-by-sonja-hannus
onnen-kuplia
rss-kuumilla-aalloilla
paritellen
katilon-kahvitunti
junnut-pelissa
rss-vapaudu-voimaasi
rss-rentoudu-podcast-rentoutumiseen-hanna-viljanmaa
kehorauhaa