Pro Pharma Talks3 Loka 2019

Gender Bias in Medicine and Drug Research

Gender Bias in Medicine and Drug Research

1. Women 51% of population, but few women in clinical research

2. Sex is based on reproductive organs and functions assigned by chromosomes

- Gender is self-representation in response to socials institutions shaped by environment and experience

- Action: Education, research, workforce development

3. Medical Biases against women

- Heart failure – Australia: women < men to receive recommended treatment for heart failure

- Alzheimer’s Disease – women perform better than men in early stages

- Medical trials – women excluded

- 8 Rx in US withdrawn between 1997-2001 for less safe and effective

- Until early 1990’s women excluded from biomedical studies

- Example:

- Women: ASA reduced risk of stroke, but not MI

- Men: ASA reduces risk of MI, but not stroke

- CPR dummies – U of Penn (2018) women less likely to receive CPR

- Endometriosis – 1/10 women wait > 7 years for diagnosis

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