Ep 54: The Promises and Perils of the Microbiome - Dr. Jonathan Eisen and Jessica Richman

Ep 54: The Promises and Perils of the Microbiome - Dr. Jonathan Eisen and Jessica Richman

By popular demand, an entire episode dedicated to exploring the microbiome! Are you really 90% bacteria and 10% human? How can you manage or optimize your own microbiome? Should we do fecal-matter transplants from "untouched" indigenous tribes to reverse chronic illness? We tackle all this and much more. Jessica Richman is co-founder and CEO of uBiome, a startup backed by Y Combinator and Andreesen Horowitz, which uses citizen science to understand the human microbiome. Jessica attended Stanford University, where she earned degrees in economics and interdisciplinary engineering. She then got a fellowship to Oxford University for her PhD in computational social science. Her work has been featured in Wired, Popular Science, MIT Technology Review, NYT, and dozens of other media outlets. Jonathan Eisen is a Full Professor at the University of California, Davis with appointments in the School of Medicine and the College of Biological Sciences. Dr. Eisen’s research focuses on the evolution, ecology and function of communities of microorganisms. His study systems have included boiling acid pools, surface ocean waters, buildings, agents of many diseases, and the microbial ecosystems (also known as microbiomes) that are found living in and on plants and animals. In addition to his research, Dr. Eisen is a vocal advocate for “open science” especially “open access” to scientific publications. He earned a Ph.D. in Biological Sciences from Stanford University and an A.B. in Biology from Harvard College.

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#842: The Story Behind EpiPen, The Rise of Food Allergies, and What Doctors Got Wrong

#842: The Story Behind EpiPen, The Rise of Food Allergies, and What Doctors Got Wrong

This time around, we have an experimental format, featuring the first episode of a brand-new podcast launching next week, Drug Story. I rarely feature episodes from other shows, but I think this one i...

30 Joulu 202558min

#841: Arthur Brooks — Finding The Meaning of Your Life, The Poet's Protocol, The Holy Half-Hour, and Why Your Suffering is Sacred

#841: Arthur Brooks — Finding The Meaning of Your Life, The Poet's Protocol, The Holy Half-Hour, and Why Your Suffering is Sacred

Arthur C. Brooks is a professor at the Harvard Kennedy School and the Harvard Business School, where he teaches courses on leadership and happiness. His next book, The Meaning of Your Life: Finding Pu...

23 Joulu 20252h 10min

#840: Bill Gurley — Investing in The AI Era, 10 Days in China, and Important Life Lessons from Bob Dylan, Jerry Seinfeld, MrBeast, and More

#840: Bill Gurley — Investing in The AI Era, 10 Days in China, and Important Life Lessons from Bob Dylan, Jerry Seinfeld, MrBeast, and More

Bill Gurley (@bgurley) is a general partner at Benchmark, a leading venture capital firm in Silicon Valley. His new book is Runnin’ Down a Dream: How to Thrive in a Career You Actually Love.This episo...

17 Joulu 20252h 10min

#839: Dr. Fei-Fei Li, The Godmother of AI — Asking Audacious Questions, Civilizational Technology, and Finding Your North Star

#839: Dr. Fei-Fei Li, The Godmother of AI — Asking Audacious Questions, Civilizational Technology, and Finding Your North Star

Dr. Fei-Fei Li (@drfeifei) is the inaugural Sequoia Professor in the Computer Science Department at Stanford University, a founding co-director of Stanford’s Human-Centered AI Institute, and the co-fo...

9 Joulu 20251h 18min

#838: The Random Show — The 2–2–2 Rule, The Future of AI, Bioelectric Medicine, Surviving Modern Dating, The Promises of DORAs for Alzheimer’s, and Wisdom from Anthony de Mello

#838: The Random Show — The 2–2–2 Rule, The Future of AI, Bioelectric Medicine, Surviving Modern Dating, The Promises of DORAs for Alzheimer’s, and Wisdom from Anthony de Mello

Welcome to another wide-ranging "Random Show" episode that I recorded with my close friend Kevin Rose (digg.com)!This episode is brought to you by:Qlosi prescription eye drop used to treat age-related...

3 Joulu 20251h 51min

#837: How to Simplify Your Life in 2026 — New Tips from Derek Sivers, Seth Godin, and Martha Beck

#837: How to Simplify Your Life in 2026 — New Tips from Derek Sivers, Seth Godin, and Martha Beck

As we head into the new year, many of us feel like we’re drowning in invisible complexity. So I wanted to hit pause and ask a simple question: What are 1-3 decisions that could dramatically simplify m...

26 Marras 202532min

#836: The 4-Hour Workweek Principles — 13 Mistakes to Avoid, The Art of Mini-Retirements, and Navigating the Dizziness of Freedom

#836: The 4-Hour Workweek Principles — 13 Mistakes to Avoid, The Art of Mini-Retirements, and Navigating the Dizziness of Freedom

This time around, we have a bit of a different format, featuring the book that started it all for me, The 4-Hour Workweek. Readers and listeners often ask me what I would change or update, but an equa...

19 Marras 20251h 37min

#835: Ben Patrick (KneesOverToesGuy) — 20-Minute Workouts That Produce Wild Results, From Chronic Knee Pain to Dunking Basketballs, Lessons from Charles Poliquin, Bulletproofing the Lower Body, and More

#835: Ben Patrick (KneesOverToesGuy) — 20-Minute Workouts That Produce Wild Results, From Chronic Knee Pain to Dunking Basketballs, Lessons from Charles Poliquin, Bulletproofing the Lower Body, and More

Ben Patrick, better known as “Kneesovertoesguy” (@kneesovertoesguy), is the founder of Athletic Truth Group (ATG), an online and brick-and-mortar training system rooted in rehabilitative strength and ...

12 Marras 20251h 37min

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