Does The Microbiome Hold The Key To Treating Parkinson’s, Autism & Other Diseases? CalTech Microbiologist Dr. Sarkis Mazmazian on The Gut-Brain Axis

Does The Microbiome Hold The Key To Treating Parkinson’s, Autism & Other Diseases? CalTech Microbiologist Dr. Sarkis Mazmazian on The Gut-Brain Axis

This week, I am joined by microbiologist Dr. Sarkis Mazmanian, the Luis B. and Nelly Soux Professor at Caltech, to discuss the microbiome's connection to human health—especially the gut-brain axis. Dr. Mazmanian discusses his research evolution from infectious diseases to the microbiome’s role in neurodevelopment and neurodegeneration, as well as how gut microbes influence neurological health, behavior, and conditions like Parkinson's, autism, and depression. He highlights the human gut microbe symbiosis, early-life microbial exposure's influence, and the adult microbiome's malleability. We explore microbiome-based therapeutics' potential, challenges in translating animal models to humans, personalized medicine's future, the microbiome's impact on drug efficacy, gut bacteria's influence on behaviors and cravings, and the importance of a healthy gut diet. Please enjoy! Show notes + MORE Watch on YouTube Newsletter Sign-Up Today’s Sponsors: AG1: Get a FREE 1-year supply of Vitamin D3+K2 AND 5 free AG1 Travel Packs 👉drinkAG1.com/richroll InsideTracker: Use code RICHROLL at checkout and enjoy 10% OFF the InsideTracker Subscription and any plan 👉insidetracker.com/richroll On: 10% OFF your first order of high-performance shoes and apparel w/ code RICHROLL10👉on.com/richroll Roka: Unlock 20% OFF sunglasses & eyewear with code RICHROLL 👉roka.com/richroll Go Brewing: Use the code Rich Roll for 15% OFF my favorite non-alcoholic brews 👉gobrewing.com Squarespace: Use the offer code RichRoll to save 10% off your first purchase of a website or domain 👉Squarespace.com/RichRoll

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The Invisible Injury: Champion Cyclist Rebecca Rusch On Healing From A Traumatic Brain Injury, Concussion Awareness & Why Acceptance Is Strength

The Invisible Injury: Champion Cyclist Rebecca Rusch On Healing From A Traumatic Brain Injury, Concussion Awareness & Why Acceptance Is Strength

Rebecca Rusch is a legendary endurance athlete, 7x world champion, and protagonist of the Emmy-winning film “Blood Road.” This conversation explores the esoteric intersection of trauma and transforma...

11 Marras 20242h

Iron Maiden’s Bruce Dickinson: The Metal God On Piloting 757s Through War Zones, Surviving Cancer, Olympic Fencing & Why He Could Be A Sleeper MI6 Agent

Iron Maiden’s Bruce Dickinson: The Metal God On Piloting 757s Through War Zones, Surviving Cancer, Olympic Fencing & Why He Could Be A Sleeper MI6 Agent

Bruce Dickinson is the legendary frontman of Iron Maiden and a true polymath—a commercial airline pilot, Olympic-caliber fencer, author, and cancer survivor. Joined by acclaimed filmmaker, close coll...

4 Marras 20242h 25min

Our Greatest Power Is Love: Julie Piatt On Transformation, Shedding Beliefs, Inner Magic & Why Being Is The Greatest State Of Awareness

Our Greatest Power Is Love: Julie Piatt On Transformation, Shedding Beliefs, Inner Magic & Why Being Is The Greatest State Of Awareness

Julie Piatt is a modern mystic, accomplished yogi, bestselling author, and the founder/CEO of SriMu, the pioneering plant-based cheese company. She’s also my wife and most frequent podcast guest. Thi...

31 Loka 20241h 44min

Rage Against The Machines: Yuval Noah Harari On Surviving AI, The History Of Information, And The Future Of Humanity

Rage Against The Machines: Yuval Noah Harari On Surviving AI, The History Of Information, And The Future Of Humanity

Yuval Noah Harari is a renowned historian, bestselling author of “Sapiens” and “Homo Deus,” and the mind behind the new book, “Nexus.” This conversation explores AI’s impact on society through Yuval’...

28 Loka 20241h 41min

Introducing Life With Machines: How An AI Song Broke The Internet (And Maybe The Music Industry Forever)

Introducing Life With Machines: How An AI Song Broke The Internet (And Maybe The Music Industry Forever)

Today I’m sharing an episode of Life With Machines—a new podcast hosted by Baratunde Thurston. Subscribe on Spotify and Apple Podcasts. Watch on YouTube. In this episode, Baratunde sits down with K...

24 Loka 20241h 47min

Elite Endurance Master Cam Wurf On Effective Training, Achievable Goals, The Power Of Consistency, & What It Takes To Win

Elite Endurance Master Cam Wurf On Effective Training, Achievable Goals, The Power Of Consistency, & What It Takes To Win

Cam Wurf is a paragon of endurance athleticism, a professional cyclist for INEOS Grenadiers, and an Ironman champion. This conversation explores Cam’s training strategies for Kona, discussing enduran...

21 Loka 20241h 38min

Tom Holland Is More Than Spider-Man: On Living Alcohol-Free, Acting With Authenticity, & Launching A Second Career

Tom Holland Is More Than Spider-Man: On Living Alcohol-Free, Acting With Authenticity, & Launching A Second Career

Tom Holland is the star of Spider-Man, a nascent entrepreneur, and one of Hollywood’s most grounded young actors. This conversation traverses the nexus of fame, personal growth, and Tom’s journey tow...

17 Loka 20241h 44min

Life After Free Solo: Alex Honnold On Risk Post Kids, Transcending Fear, Parenting, The Devil’s Climb, & More

Life After Free Solo: Alex Honnold On Risk Post Kids, Transcending Fear, Parenting, The Devil’s Climb, & More

Alex Honnold is a global climbing icon, founder of the Honnold Foundation, and the protagonist in the Oscar-winning documentary “Free Solo.” This conversation explores the confluence of extreme athle...

14 Loka 20241h 43min

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