Does The Microbiome Hold The Key To Treating Parkinson’s, Autism & Other Diseases? CalTech Microbiologist Dr. Sarkis Mazmazian on The Gut-Brain Axis

Does The Microbiome Hold The Key To Treating Parkinson’s, Autism & Other Diseases? CalTech Microbiologist Dr. Sarkis Mazmazian on The Gut-Brain Axis

This week, I am joined by microbiologist Dr. Sarkis Mazmanian, the Luis B. and Nelly Soux Professor at Caltech, to discuss the microbiome's connection to human health—especially the gut-brain axis. Dr. Mazmanian discusses his research evolution from infectious diseases to the microbiome’s role in neurodevelopment and neurodegeneration, as well as how gut microbes influence neurological health, behavior, and conditions like Parkinson's, autism, and depression. He highlights the human gut microbe symbiosis, early-life microbial exposure's influence, and the adult microbiome's malleability. We explore microbiome-based therapeutics' potential, challenges in translating animal models to humans, personalized medicine's future, the microbiome's impact on drug efficacy, gut bacteria's influence on behaviors and cravings, and the importance of a healthy gut diet. Please enjoy! Show notes + MORE Watch on YouTube Newsletter Sign-Up Today’s Sponsors: AG1: Get a FREE 1-year supply of Vitamin D3+K2 AND 5 free AG1 Travel Packs 👉drinkAG1.com/richroll InsideTracker: Use code RICHROLL at checkout and enjoy 10% OFF the InsideTracker Subscription and any plan 👉insidetracker.com/richroll On: 10% OFF your first order of high-performance shoes and apparel w/ code RICHROLL10👉on.com/richroll Roka: Unlock 20% OFF sunglasses & eyewear with code RICHROLL 👉roka.com/richroll Go Brewing: Use the code Rich Roll for 15% OFF my favorite non-alcoholic brews 👉gobrewing.com Squarespace: Use the offer code RichRoll to save 10% off your first purchase of a website or domain 👉Squarespace.com/RichRoll

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Introducing Mentor Buffet: Zach Braff—Be Yourself Until Somebody Gives You a Chance

Introducing Mentor Buffet: Zach Braff—Be Yourself Until Somebody Gives You a Chance

Today I’m sharing an episode of Mentor Buffet—a new podcast hosted by Alexi Pappas, the Olympian-author-filmmaker. Subscribe on Spotify and Apple Podcasts Watch on YouTube In each episode, Alexi g...

10 Loka 20241h 11min

Never Play It Safe: Chase Jarvis On Risk, Creativity, & 7 Tools To Build The Life You Want

Never Play It Safe: Chase Jarvis On Risk, Creativity, & 7 Tools To Build The Life You Want

Chase Jarvis is a renowned photographer, creative entrepreneur, and author of the new book “Never Play It Safe.” This conversation surveys Chase’s perspective on creativity and personal growth, empha...

7 Loka 20242h 13min

ROLL ON: Alt Media, Streaming Rec’s, AMA, & The Truth About Transformation

ROLL ON: Alt Media, Streaming Rec’s, AMA, & The Truth About Transformation

Adam and I are back on the mics for another rollicking “Roll On”—ready to dissect the kaleidoscope of experiences that have colored our recent existence! We free dive into Adam’s aquatic adventures w...

3 Loka 20241h 59min

The 5 Pillars of Fulfilling Aging: Outdoor Adventurer Caroline Paul On Chasing Risk After 60, & Why Age Is Just A Mindset

The 5 Pillars of Fulfilling Aging: Outdoor Adventurer Caroline Paul On Chasing Risk After 60, & Why Age Is Just A Mindset

Caroline Paul, a bestselling author, ex-firefighter, and adventurer, is here with her latest book “Tough Broad,” which explores how nature redefines aging. This conversation explores the insidious cu...

30 Syys 20242h 1min

The How of Happiness: Psychologist Sonja Lyubomirsky On Connection, Gratitude, Kindness, MDMA, & Other Tools For Greater Joy

The How of Happiness: Psychologist Sonja Lyubomirsky On Connection, Gratitude, Kindness, MDMA, & Other Tools For Greater Joy

Dr. Sonja Lyubomirsky is a pioneering happiness researcher, bestselling author, and Distinguished Professor of Psychology at UC Riverside. This conversation explores the cutting-edge science of happi...

23 Syys 20241h 53min

Dispatches From The Death Zone: Adrian Ballinger On Risk, Reward, & Guiding Earth’s Biggest Mountains

Dispatches From The Death Zone: Adrian Ballinger On Risk, Reward, & Guiding Earth’s Biggest Mountains

Adrian Ballinger is an elite mountaineer, a 9-time Everest summiteer, and the founder of Alpenglow Expeditions. This conversation delves into Adrian’s Everest ascents, his “Rapid Ascent” method, view...

19 Syys 20242h 10min

Ignite Your Evolution: Hakim Tafari is a Master of Mindfulness, Curator of Culture, & The Journeyman of Reinvention

Ignite Your Evolution: Hakim Tafari is a Master of Mindfulness, Curator of Culture, & The Journeyman of Reinvention

Hakim Tafari is a journeyman of reinvention, master of mindfulness, and martial arts practitioner. This conversation explores Hakim’s philosophy of surrender as a superpower and his “Sure Hearts Rele...

16 Syys 20242h 7min

The 5 Stages Of The Heart: Science-Backed Practices To Empower Your Thoughts, Balance Your Emotions, And Unlock Vibrant Health

The 5 Stages Of The Heart: Science-Backed Practices To Empower Your Thoughts, Balance Your Emotions, And Unlock Vibrant Health

Kimberly Snyder is a renowned nutritionist, New York Times bestselling author, and wellness expert. This conversation explores the nexus of ancient wisdom and cutting-edge science in Kimberly’s icono...

9 Syys 20241h 41min

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