Towards model-informed precision dosing of piperacillin: multicenter systematic external evaluation of pharmacokinetic models in critically ill adults with a focus on Bayesian forecasting
Numerous Population Pharmacokinetic (PopPK) models have been developed for Piperacillin (PIP), most of which are based on small monocentric studies and may not be generalizable to other populations. A...
14 Helmi 202417min
Green ICU - Environmental Sustainability in intensive care
The concept of a "green ICU" is increasingly important in today's world, as sustainability and environmental considerations become integral to healthcare practices. Hospitals, including ICUs, can have...
7 Helmi 202412min
Diving into ARDS with Prof. Gattinoni. From the new guidelines to bedside applied physiology.
Acute respiratory distress syndrome (ARDS) is the term applied to a spectrum of conditions with different etiologies that share common clinical-pathological characteristics including: increased perme...
20 Joulu 202339min
Sepsis-associated acute kidney injury in the intensive care unit. A multicenter observational study
Sepsis‐associated acute kidney injury (SA‐AKI) is a common, increasingly prevalent problem in the intensive care unit (ICU). The association between sepsis and AKI has been studied previously. However...
8 Marras 202315min
Patient Transportation in Critical Care: introduction to our ACE course
Transportation of critically ill patients is inevitable in most health systems. Prehospital transportation (PHT) may be necessary after a major injury or as a result of a life-threatening illness – fo...
4 Loka 202312min
Interprofessional teamwork in ICU
Intensive care units (ICU) are the most peculiar units in hospitals where the quality and safety of health care delivery should be at the highest level. The most critical patients are treated in this ...
27 Syys 202324min
Artesunate treatment in severely injured patients with traumatic haemorrhage
Multiple organ dysfunction syndrome (MODS) is common after major trauma, affecting up to two-thirds of patients with critical injuries. Post-trauma MODS is associated with a mortality of over 20% and ...
20 Syys 202318min
Life after sepsis in adult and paediatric patients
Sepsis is a life-threatening acute organ dysfunction secondary to infection and affects more than 19 million people annually. In 2017, it was estimated that almost 49 million people were infected by s...
13 Syys 202325min
