112 | Fyodor Urnov on Gene Editing, CRISPR, and Human Engineering

112 | Fyodor Urnov on Gene Editing, CRISPR, and Human Engineering

Not too long ago nobody carried a mobile phone; now almost everybody does. That's the kind of rate of rapid progress we're seeing with our ability to directly edit genomes. With the use of CRISPR-Cas9 and other techniques, gene editing is becoming commonplace. How does that work — and perhaps more importantly, how are we going to put it to use? Fyodor Urnov has worked in this area from its beginning, having coined the term "gene editing." We talk about how this new technology can be used to cure or prevent disease, as well as the pros and cons of designer babies.

Support Mindscape on Patreon.

Fyodor Urnov received his Ph.D. in Biology from Brown University. He is currently professor of Genetic, Genomics, and Development in the Department of Molecular and Cell Biology at UC Berkeley, as well as Director for Technology and Translation at the Innovative Genomics Institute. His research focuses on using CRISPR gene-editing techniques to develop treatments for sickle cell disease, radiation injury, and other conditions, as well as guiding IGI researchers as they bring these therapies from the lab to the clinic.

Todays episode is sponsored by The Great Courses Plus. Mindscape listeners get a free trial if they sign up at http://thegreatcoursesplus.com/mindscape.

Jaksot(416)

285 | Nate Silver on Prediction, Risk, and Rationality

285 | Nate Silver on Prediction, Risk, and Rationality

Being rational necessarily involves engagement with probability. Given two possible courses of action, it can be rational to prefer the one that could possibly result in a worse outcome, if there's al...

12 Elo 20241h 11min

AMA | August 2024

AMA | August 2024

Welcome to the August 2024 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patr...

5 Elo 20243h 37min

284 | Doris Tsao on How the Brain Turns Vision Into the World

284 | Doris Tsao on How the Brain Turns Vision Into the World

The human brain does a pretty amazing job of taking in a huge amount of data from multiple sensory modalities -- vision, hearing, smell, etc. -- and constructing a coherent picture of the world, const...

29 Heinä 20241h 2min

283 | Daron Acemoglu on Technology, Inequality, and Power

283 | Daron Acemoglu on Technology, Inequality, and Power

Change is scary. But sometimes it can all work out for the best. There's no guarantee of that, however, even when the change in question involves the introduction of a powerful new technology. Today's...

22 Heinä 20241h 17min

282 | Joel David Hamkins on Puzzles of Reality and Infinity

282 | Joel David Hamkins on Puzzles of Reality and Infinity

The philosophy of mathematics would be so much easier if it weren't for infinity. The concept seems natural, but taking it seriously opens the door to counterintuitive results. As mathematician and ph...

15 Heinä 20241h 18min

Ask Me Anything | July 2024

Ask Me Anything | July 2024

Welcome to the July 2024 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreo...

8 Heinä 20243h 21min

281 | Samir Okasha on the Philosophy of Agency and Evolution

281 | Samir Okasha on the Philosophy of Agency and Evolution

Just like with physics, in biology it is perfectly possible to do most respectable work without thinking much about philosophy, but there are unmistakably foundational questions where philosophy becom...

1 Heinä 20241h 11min

280 | François Chollet on Deep Learning and the Meaning of Intelligence

280 | François Chollet on Deep Learning and the Meaning of Intelligence

Which is more intelligent, ChatGPT or a 3-year old? Of course this depends on what we mean by "intelligence." A modern LLM is certainly able to answer all sorts of questions that require knowledge far...

24 Kesä 20241h 41min

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