112 | Fyodor Urnov on Gene Editing, CRISPR, and Human Engineering

112 | Fyodor Urnov on Gene Editing, CRISPR, and Human Engineering

Not too long ago nobody carried a mobile phone; now almost everybody does. That's the kind of rate of rapid progress we're seeing with our ability to directly edit genomes. With the use of CRISPR-Cas9 and other techniques, gene editing is becoming commonplace. How does that work — and perhaps more importantly, how are we going to put it to use? Fyodor Urnov has worked in this area from its beginning, having coined the term "gene editing." We talk about how this new technology can be used to cure or prevent disease, as well as the pros and cons of designer babies.

Support Mindscape on Patreon.

Fyodor Urnov received his Ph.D. in Biology from Brown University. He is currently professor of Genetic, Genomics, and Development in the Department of Molecular and Cell Biology at UC Berkeley, as well as Director for Technology and Translation at the Innovative Genomics Institute. His research focuses on using CRISPR gene-editing techniques to develop treatments for sickle cell disease, radiation injury, and other conditions, as well as guiding IGI researchers as they bring these therapies from the lab to the clinic.

Todays episode is sponsored by The Great Courses Plus. Mindscape listeners get a free trial if they sign up at http://thegreatcoursesplus.com/mindscape.

Jaksot(416)

AMA | October 2024

AMA | October 2024

Welcome to the October 2024 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Pat...

7 Loka 20244h 29min

291 | Venki Ramakrishnan on the Biology of Death and Aging

291 | Venki Ramakrishnan on the Biology of Death and Aging

Aging and death happen to the best of us, but there are increasing efforts to do something about it. That effort requires that we have some reasonable understanding of why aging happens, and what proc...

30 Syys 20241h 20min

290 | Hahrie Han on Making Multicultural Democracy Work

290 | Hahrie Han on Making Multicultural Democracy Work

It's a wonder democracy works at all -- a collection of people with potentially different interests have to agree to abide by majority vote even when it goes against their desires. But as we know, it ...

23 Syys 20241h 15min

289 | Cari Cesarotti on the Next Generation of Particle Experiments

289 | Cari Cesarotti on the Next Generation of Particle Experiments

As an experimental facility, the Large Hadron Collider at CERN in Geneva has been extraordinarily successful, discovering the Higgs boson and measuring multiple features of particle-physics interactio...

16 Syys 20241h 21min

288 | Max Richter on the Meaning of Classical Music Today

288 | Max Richter on the Meaning of Classical Music Today

It wasn't that long ago, historically speaking, that you might put on your tuxedo or floor-length evening gown to go out and hear a live opera or symphony. But today's world is faster, more technologi...

9 Syys 20241h 6min

AMA | September 2024

AMA | September 2024

Welcome to the September 2024 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by P...

2 Syys 20243h 50min

287 | Jean-Paul Faguet on Institutions and the Legacy of History

287 | Jean-Paul Faguet on Institutions and the Legacy of History

One common feature of complex systems is sensitive dependence on initial conditions: a small change in how systems begin evolving can lead to large differences in their later behavior. In the social s...

26 Elo 20241h 32min

286 | Blaise Agüera y Arcas on the Emergence of Replication and Computation

286 | Blaise Agüera y Arcas on the Emergence of Replication and Computation

Understanding how life began on Earth involves questions of chemistry, geology, planetary science, physics, and more. But the question of how random processes lead to organized, self-replicating, info...

19 Elo 20241h 20min

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