112 | Fyodor Urnov on Gene Editing, CRISPR, and Human Engineering

112 | Fyodor Urnov on Gene Editing, CRISPR, and Human Engineering

Not too long ago nobody carried a mobile phone; now almost everybody does. That's the kind of rate of rapid progress we're seeing with our ability to directly edit genomes. With the use of CRISPR-Cas9 and other techniques, gene editing is becoming commonplace. How does that work — and perhaps more importantly, how are we going to put it to use? Fyodor Urnov has worked in this area from its beginning, having coined the term "gene editing." We talk about how this new technology can be used to cure or prevent disease, as well as the pros and cons of designer babies.

Support Mindscape on Patreon.

Fyodor Urnov received his Ph.D. in Biology from Brown University. He is currently professor of Genetic, Genomics, and Development in the Department of Molecular and Cell Biology at UC Berkeley, as well as Director for Technology and Translation at the Innovative Genomics Institute. His research focuses on using CRISPR gene-editing techniques to develop treatments for sickle cell disease, radiation injury, and other conditions, as well as guiding IGI researchers as they bring these therapies from the lab to the clinic.

Todays episode is sponsored by The Great Courses Plus. Mindscape listeners get a free trial if they sign up at http://thegreatcoursesplus.com/mindscape.

Jaksot(416)

AMA | December 2024

AMA | December 2024

Welcome to the December 2024 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Pa...

2 Joulu 20243h 55min

297 | Emily Wilson on Homer, Poetry, and Translation

297 | Emily Wilson on Homer, Poetry, and Translation

Not too long ago, Brad Pitt and Eric Bana starred in a (loose) adaptation of Homer's epic poem The Iliad; next month, Ralph Fiennes and Juliette Binoche will headline a film based on The Odyssey. Give...

25 Marras 20241h 15min

296 | Brandon Ogbunu on Fitness Seascapes and the Course of Evolution

296 | Brandon Ogbunu on Fitness Seascapes and the Course of Evolution

Biological evolution via natural selection is a simple idea that becomes enormously complicated in its realization. Populations of organisms are driven toward increased "fitness," a measure of how suc...

18 Marras 20241h 15min

295 | Solo: Emergence and Layers of Reality

295 | Solo: Emergence and Layers of Reality

Emergence is a centrally important concept in science and philosophy. Indeed, the existence of higher-level emergent properties helps render the world intelligible to us -- we can sensibly understand ...

11 Marras 20241h 35min

AMA | November 2024

AMA | November 2024

Welcome to the November 2024 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Pa...

4 Marras 20243h 50min

294 | Addy Pross on Dynamics, Stability, and Life

294 | Addy Pross on Dynamics, Stability, and Life

Erwin Schrödinger said that the important characteristic of life is that it "goes on doing something... for a much longer period than we would expect an inanimate piece of matter to keep going under s...

28 Loka 20241h 11min

293 | Doyne Farmer on Chaos, Crashes, and Economic Complexity

293 | Doyne Farmer on Chaos, Crashes, and Economic Complexity

A large economy is one of the best examples we have of complex dynamics. There are multiple components arranged in complicated overlapping hierarchies, out-of-equilibrium dynamics, nonlinear coupling ...

21 Loka 20241h 11min

292 | Jonathan Birch on Animal Sentience

292 | Jonathan Birch on Animal Sentience

It's not immoral to kick a rock; it is immoral to kick a baby. At what point do we start saying that it is wrong to cause pain to something? This question has less to do with "consciousness" and more ...

14 Loka 20241h 10min

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