Episode 171: 171.  Diabetes Drugs, Statins and Muscle Pain, Vitamin D and COVID, Acne and Food

Episode 171: 171. Diabetes Drugs, Statins and Muscle Pain, Vitamin D and COVID, Acne and Food

SGLT2 inhibitors and GLP1 agonists administered without metformin compared to other glucose‐lowering drugs in patients with type 2 diabetes mellitus to prevent cardiovascular events: A systematic review - Escobar - 2021 - Diabetic Medicine - Wiley Online Library

Yes these fancy new drugs work with and without metformin but that does not mean these drugs should be first line!!


Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19: A Randomized Clinical Trial | Complementary and Alternative Medicine | JAMA | JAMA Network


Yep even 200,000IU of vit D does nothing except raise your vit d level.

Diet and acne: review of the evidence from 2009 to 2020 - Dall’Oglio - - International Journal of Dermatology - Wiley Online Library


What you eat does mess with your acne, or at least says this large observational trial.


Statin treatment and muscle symptoms: series of randomised, placebo controlled n-of-1 trials | The BMJ

The muscle aches with statins is a common event that it occurs as frequently with the active drug as it does with placebo

Jaksot(385)

Episode 286: 285. Does Exercise Improve Hip OA?

Episode 286: 285. Does Exercise Improve Hip OA?

https://www.acpjournals.org/doi/10.7326/M23-3225researchers randomized 160 patients with mostly unilateral hip OA to two 60-minute sessions weekly for 12 weeks,you were randomized to receive either ne...

14 Touko 20245min

Episode 285: 284. Do Electronic Cigarettes Increase Smoking Cessation?

Episode 285: 284. Do Electronic Cigarettes Increase Smoking Cessation?

adult smokers who are given e-cigarettes are significantly more likely to be abstinent at 6 months from a target quit date with a  (NNT = 8) but those individuals were not more likely to be abstinent ...

13 Touko 20247min

Episode 284: 283. New Guidelines from American College of Cardiology on Atrial Fibrillation

Episode 284: 283. New Guidelines from American College of Cardiology on Atrial Fibrillation

However, screening is not recommended because it has not been shown to improve patient outcomes.. Lifestyle recommendations include moderating alcohol use, quitting smoking, exercising, and losing wei...

9 Touko 20248min

Episode 283: 282. New Guidelines For Management of Acute Pancreatitis

Episode 283: 282. New Guidelines For Management of Acute Pancreatitis

https://journals.lww.com/ajg/fulltext/2024/03000/american_college_of_gastroenterology_guidelines_.14.aspx2 of the 3 following criteria: (i) abdominal pain consistent with the disease, (ii) serum amyla...

3 Touko 20247min

Episode 282: 281. What Do You Do With Elevated Childhood Cholesterol?

Episode 282: 281. What Do You Do With Elevated Childhood Cholesterol?

Bottom line-Elevated cholesterol as a child into an adult is bad but we still don’t know if treating children with medication improves this badness but we can say if you have elevated cholesterol as a...

2 Touko 20246min

Episode 281: 280. How Much Weight Does an Obese Mother Need to Gain?

Episode 281: 280. How Much Weight Does an Obese Mother Need to Gain?

Weight gain <5 kg was not associated with risk for the composite outcome among women with class 1 and 2 obesity (BMIs, ≥30–39.9 kg/m2). Weight gain <5 kg and weight loss were associated with lower ris...

1 Touko 20245min

Episode 280: 279. Does Sitting In a Chair Improve Patient Stay in the Hospital?

Episode 280: 279. Does Sitting In a Chair Improve Patient Stay in the Hospital?

Chair placement was not associated with a difference in patients’ ability to name their physician (P=1.0), ability to successfully identify their reason for hospital admission (P=0.82), or perceptions...

29 Huhti 20247min

Episode 279: 278. Does a Swiss Ball Help During Labor and Delivery?

Episode 279: 278. Does a Swiss Ball Help During Labor and Delivery?

primary outcome was Duration of the first stage of labor was the primary outcome. AND It was 179 minutes shorter (95% CI 146 - 213) in the intervention group than in the control group (392 minutes; st...

26 Huhti 20248min

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