Episode 171: 171.  Diabetes Drugs, Statins and Muscle Pain, Vitamin D and COVID, Acne and Food

Episode 171: 171. Diabetes Drugs, Statins and Muscle Pain, Vitamin D and COVID, Acne and Food

SGLT2 inhibitors and GLP1 agonists administered without metformin compared to other glucose‐lowering drugs in patients with type 2 diabetes mellitus to prevent cardiovascular events: A systematic review - Escobar - 2021 - Diabetic Medicine - Wiley Online Library

Yes these fancy new drugs work with and without metformin but that does not mean these drugs should be first line!!


Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19: A Randomized Clinical Trial | Complementary and Alternative Medicine | JAMA | JAMA Network


Yep even 200,000IU of vit D does nothing except raise your vit d level.

Diet and acne: review of the evidence from 2009 to 2020 - Dall’Oglio - - International Journal of Dermatology - Wiley Online Library


What you eat does mess with your acne, or at least says this large observational trial.


Statin treatment and muscle symptoms: series of randomised, placebo controlled n-of-1 trials | The BMJ

The muscle aches with statins is a common event that it occurs as frequently with the active drug as it does with placebo

Jaksot(385)

Episode 246: 246. In Giant Cell Arteritis How Soon Do You Need To Get A Biopsy After Starting Steroids?

Episode 246: 246. In Giant Cell Arteritis How Soon Do You Need To Get A Biopsy After Starting Steroids?

Just get he biopsy at less than 6 weeks after starting therapy as the yield was the same at 2 weeks as it was at 4-6 weekshttps://pubmed.ncbi.nlm.nih.gov/36642440/

23 Helmi 20244min

Episode 245: 245. Do Baby Walkers Cause Developmental Delays?

Episode 245: 245. Do Baby Walkers Cause Developmental Delays?

Evidence against baby walker is not enough regarding its negative effect on child development. This subject needs to be addressed more, considering a large number of baby walker users worldwide.https:...

22 Helmi 202420min

Episode 244: 244. Does Testosterone CAUSE Prostate Cancer?

Episode 244: 244. Does Testosterone CAUSE Prostate Cancer?

During average follow-up of in this study the incidence of prostate cancer was less than 1% — and not significantly different  Remember most of these pts had testosterone levels around 350 ish give or...

20 Helmi 20244min

Episode 243: 243. Can Testosterone Improve or Treat Depression?

Episode 243: 243. Can Testosterone Improve or Treat Depression?

From a mean score of 45 points at baseline, mood improved by about 5 points in the placebo group and 6 points in the testosterone group — a statistically significant but small difference. I think you ...

19 Helmi 20246min

Episode 242: 242. Does Testosterone Improve Sexual Function and Erectile Dysfunction?

Episode 242: 242. Does Testosterone Improve Sexual Function and Erectile Dysfunction?

Erectile disfunction should be treated with the appropriate medications like the PDE5 inhbitors—not testosterone—testosterone may make it so you flirt half a time more a day but that is not likely wor...

16 Helmi 20248min

Episode 241: 241. Does Testosterone Therapy Prevent or Cause Fractures?

Episode 241: 241. Does Testosterone Therapy Prevent or Cause Fractures?

even at very small some would argue barely even treating doses of testosterone patients had an increase rate of fractures with a NNH of 100—when you add this to the 1 risk of aki and 2 percent risk of...

15 Helmi 20245min

Episode 240: 240. Does Testosterone Prevent the Progression of Pre-diabetes to Diabetes?

Episode 240: 240. Does Testosterone Prevent the Progression of Pre-diabetes to Diabetes?

Risk of progression from prediabetes to diabetes did not differ significantly between testosterone and placebo groups- and they looked for a change at 6,12,24,36,48 months of follow upNot to sound lik...

14 Helmi 20245min

Episode 239: 239. TRAVERSE Study...Is Testosterone Therapy Safe for the Heart?

Episode 239: 239. TRAVERSE Study...Is Testosterone Therapy Safe for the Heart?

Take awayThe drug companies will say look how safe testosterone therapy is there was no difference in death from cardiovascular causes or myocardial infarction or stroke in those individuals randomize...

13 Helmi 202410min

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