Episode 171: 171.  Diabetes Drugs, Statins and Muscle Pain, Vitamin D and COVID, Acne and Food

Episode 171: 171. Diabetes Drugs, Statins and Muscle Pain, Vitamin D and COVID, Acne and Food

SGLT2 inhibitors and GLP1 agonists administered without metformin compared to other glucose‐lowering drugs in patients with type 2 diabetes mellitus to prevent cardiovascular events: A systematic review - Escobar - 2021 - Diabetic Medicine - Wiley Online Library

Yes these fancy new drugs work with and without metformin but that does not mean these drugs should be first line!!


Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19: A Randomized Clinical Trial | Complementary and Alternative Medicine | JAMA | JAMA Network


Yep even 200,000IU of vit D does nothing except raise your vit d level.

Diet and acne: review of the evidence from 2009 to 2020 - Dall’Oglio - - International Journal of Dermatology - Wiley Online Library


What you eat does mess with your acne, or at least says this large observational trial.


Statin treatment and muscle symptoms: series of randomised, placebo controlled n-of-1 trials | The BMJ

The muscle aches with statins is a common event that it occurs as frequently with the active drug as it does with placebo

Jaksot(385)

Episode 238: 238. What to do With Low Risk Pulmonary Embolism?

Episode 238: 238. What to do With Low Risk Pulmonary Embolism?

Use the PE Severity Index. If low risk and that is the only reason for admission, then the patient is safe for dischargehttps://www.thelancet.com/journals/lancet/article/PIIS0140-6736(11)60824-6/abstr...

12 Helmi 20245min

Episode 237: 237. Big Take Away from ACP Update to Colon Cancer Screening

Episode 237: 237. Big Take Away from ACP Update to Colon Cancer Screening

american college of physicians says- No need to start colon cancer screening prior to 50. stop at age 75 or with 10 yrs of life left and FIT testing can be every other year and Cologuard is not recomm...

9 Helmi 20245min

Episode 236: 236. Is Weight Loss Beneficial For Hip Osteoarthritis?

Episode 236: 236. Is Weight Loss Beneficial For Hip Osteoarthritis?

While weight loss may be beneficial for individuals with knee osteoarthritis, it does not see to have a protective or beneficial effect for those with hip osteoarthritis. https://agsjournals.onlinelib...

8 Helmi 20244min

Episode 235: 235. When Should A Patient With HIV Be Started On Statin Therapy?

Episode 235: 235. When Should A Patient With HIV Be Started On Statin Therapy?

In patients with HIV and cv risk score of 4.5% there was a NNT of 106 at 5 yrs of follow up to prevent 1 MACEhttps://www.acpjournals.org/doi/10.7326/M22-2643?url_ver=Z39.88-2003&rfr_id=ori:rid:crossre...

7 Helmi 20244min

Episode 234: 234. Does Size Matter...BP Cuff Size

Episode 234: 234. Does Size Matter...BP Cuff Size

A cuff 1-2 sizes too large underestimated bp by 4-9mm Hg BUT a cuff 1-2 sizes too small overestimated the BP 4-20mm Hghttps://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2807853

6 Helmi 20245min

Episode 233: 233. Do GLP1 agonist actually delay gastric emptying?

Episode 233: 233. Do GLP1 agonist actually delay gastric emptying?

GLP1 agonist likely lead to retained gastric products but this effect is larger for once weekly injections than once daily pills.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204182/

5 Helmi 20246min

Episode 232: 232. Is the HPV vaccine that good?

Episode 232: 232. Is the HPV vaccine that good?

During 28 months of follow-up, absolute risks for progression from CIN2 to CIN3 (or worse) were as follows: 23% among women vaccinated before age 15 32% among women vaccinated between ages 15 and 20 3...

2 Helmi 20248min

Episode 231: 231. Is Cancer Actually Associated with Weight Loss?

Episode 231: 231. Is Cancer Actually Associated with Weight Loss?

>10% unintentional weight loss is most likely associated with  gastrointestinal, liver, pancreatic, and biliary cancers (relative risks, 3.1–7.4); Leukemia (RR, 4.2) Breast, prostate, and gynecologic ...

1 Helmi 20245min

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