Episode 203: 203. Medical Update 203 -- HEAD CT, Weekend warrior, REDUCE-IT, SGLT-2, HF, DMARD, Blood test

Episode 203: 203. Medical Update 203 -- HEAD CT, Weekend warrior, REDUCE-IT, SGLT-2, HF, DMARD, Blood test

https://www.ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.122.059410?af=R

The Biomarkers say REDUCE-IT was a scam

https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2791663

NO! Just NO-- stick with the calculator for now

https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.059038

start the SLGT-2 inhibitors early! maybe an early discharge

https://pubmed.ncbi.nlm.nih.gov/35849407/

If we could get the EMR to do it automatically else you cant expect providers to

https://pubmed.ncbi.nlm.nih.gov/35727595/

the head CT for psych stuff can probably be put on hold

https://eprints.whiterose.ac.uk/180135/

continue the disease modifying agents

Jaksot(386)

Episode 376: 387. Methods Monday and an Example of Subgroup Analysis

Episode 376: 387. Methods Monday and an Example of Subgroup Analysis

https://www.nejm.org/doi/full/10.1056/NEJMoa2405923?query=clinical-medicine Mineralocorticoid receptor antagonists have been shown to reduce mortality in patients after myocardial infarction with cong...

17 Maalis 20258min

Episode 375: 386. Could half dose anticoagulation be the answer?

Episode 375: 386. Could half dose anticoagulation be the answer?

Estimated 5-year incidence of recurrent VTE was similar in the reduced-dose and full-dose groups (2.2% and 1.8%). Estimated 5-year bleeding incidence was significantly lower with reduced-dose than wi...

14 Maalis 20258min

Episode 374: 385. PRACTICE CHANGER! Male-Partner Treatment to Prevent Recurrence of Bacterial Vaginosis

Episode 374: 385. PRACTICE CHANGER! Male-Partner Treatment to Prevent Recurrence of Bacterial Vaginosis

https://www.nejm.org/doi/full/10.1056/NEJMoa2405404NNT of 4! systemic metronid and topical clinda bid for one week

12 Maalis 20256min

Episode 373: 384. Chronic Kidney Disease and Empagliflozin Legacy Effect

Episode 373: 384. Chronic Kidney Disease and Empagliflozin Legacy Effect

What Was Studied?The EMPA-KIDNEY trial followed 6,609 CKD patients at risk of disease progression. Participants were randomly assigned to receive empagliflozin (10 mg daily) or a placebo for a median ...

11 Maalis 20259min

Episode 372: 383. What is the GFR at which we stop metforin?

Episode 372: 383. What is the GFR at which we stop metforin?

Metformin while not necessarily first line therapy for diabetes depending on the patients co-morbid conditions it is certainly highly ranked on the list of medications! I know often metformin is stopp...

6 Maalis 202510min

Episode 371: 382. Is it safe to give the flu and covid vaccine at the same time?

Episode 371: 382. Is it safe to give the flu and covid vaccine at the same time?

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2825813Conclusions and Relevance  In this randomized clinical trial assessing simultaneous vs sequential administration of mRNA COVID-19 an...

4 Maalis 20257min

Episode 370: 381. Relative efficacy of prehabilitation interventions and their components

Episode 370: 381. Relative efficacy of prehabilitation interventions and their components

https://www.bmj.com/content/388/bmj-2024-081164systematic review and meta-analysis on prehabilitation before surgery, published in the BMJ in February 2025.Prehabilitation aims to prepare patients for...

27 Helmi 20257min

Episode 369: 380. REPOST mammo part 2

Episode 369: 380. REPOST mammo part 2

Mammograms

24 Helmi 202520min

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