Episode 342: 341. Methods Monday! What is the problem with stopping a trial EARLY?
Stopping Trials Early for Benefit: Insights From Recent Pivotal Trials in Chronic Kidney Disease - ScienceDirect There are 4 major reasons why trials might be stopped early: 1) unequivocal benefit; ...
4 Marras 20248min
Episode 341: 340. ACOI -- Vitamin D and Calcium Made Easy
You get the CME knowledge without the CME payment!
30 Loka 202438min
Episode 340: 339. Reaction Risk to Direct Penicillin Challenges
10% of hospitalized patients have penicillin allergy listed in their records, fewer than 1% of patients have true allergies. Use of more-expensive and broader-spectrum antibiotics is associated with l...
29 Loka 20245min
Episode 339: 338. Hypertension Treatment With New Triple Single Pill Combination
Efficacy and Safety of a Novel Low-Dose Triple Single-Pill Combination Compared With Placebo for Initial Treatment of HypertensionJ Am Coll Cardiol 2024 Aug 30;[EPub Ahead of Print], A Rodgers, A Sala...
25 Loka 20249min
Episode 338: 337. What is the ideal Vitamin D Level to target?
In 2011, the Endocrine Society published a guideline on “Evaluation, Treatment, and Prevention of Vitamin D Deficiency” Now, the Society has issued an updated guideline, Demay MB et al. Vitamin D fo...
22 Loka 20245min
Episode 337: 336. 24 Hours After a Stroke for EVT- 2 yr Follow-Up
Huijberts I et al. Collateral-based selection for endovascular treatment of acute ischaemic stroke in the late window (MR CLEAN-LATE): 2-year follow-up of a phase 3, multicentre, open-label, randomise...
18 Loka 20246min
Episode 336: 335. Do GLP-1 Cause Residual Gastric Contents
Because glucagon-like peptide-1 (GLP-1) receptor agonists can slow gastric emptying, they might confer risk for residual gastric contents — and possibly aspiration!!!! Should we stop the glp-1 Should ...
10 Loka 20245min
Episode 335: 334. Do Thicken Liquids Prevent Dysphagia?
Oropharyngeal dysphagia is highly prevalent in hospitalized patients with Alzheimer disease or other dementias. These patients often are prescribed thick liquid diets Makhnevich A et al. Thick liquids...
8 Loka 20245min
