Episode 270: 269. What is the Harm in Aspirin?

Episode 270: 269. What is the Harm in Aspirin?

The trial was terminated after 1015 patients with atrial cardiopathy had been randomized to receive either apixaban or aspirin for a mean follow-up of 1.8 years, recurrent stroke rates were identical (40 events per group; 4.4% annualized rate). There were 7 symptomatic intracranial hemorrhages in the aspirin group and none in the apixaban group, though other major hemorrhages occurred at similar rates

Aspirin is not benign and has real risk--

BTW don't give anticoagulation if the patient does not have atrial fib.

https://jamanetwork.com/journals/jama/article-abstract/2814933

Jaksot(385)

159. Alzheimer's Disease and Financial Events --JAMA

159. Alzheimer's Disease and Financial Events --JAMA

Alzheimers disease—doesn’t say what you think it says https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/jamainternmed.2020.6432?guestAccessKey=807ca0d3-63aa-48f9-8a1d-16df0d828...

4 Joulu 202014min

158. Levothyroxine VS Synthroid And TSH

158. Levothyroxine VS Synthroid And TSH

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2771041#:~:text=Conclusions%20and%20Relevance%20Initiation%20of,effective%20as%20brand%2Dname%20levothyroxine. Comparative Effectiveness of...

1 Joulu 20207min

157. Thankful For Well Done Studies & Errors In Lab Values

157. Thankful For Well Done Studies & Errors In Lab Values

www.bmj.com/content/368/bmj.m149No one wants to get pregnant two minutes after having a baby. And also agrees that an IUD is most effective form of conception. However placing IUD after delivering a c...

26 Marras 202023min

156. Mask, COVID-19, Annals of Internal Medicine

156. Mask, COVID-19, Annals of Internal Medicine

Questioning medicine dailyhttps://www.acpjournals.org/doi/10.7326/M20-7448 https://www.acpjournals.org/doi/10.7326/M20-6817 Effectiveness of Adding a Mask Recommendation to Other Public Health Measure...

19 Marras 202015min

155. Lancet and Statin in the Elderly

155. Lancet and Statin in the Elderly

https://www.clinicalkey.com/#!/content/journal/1-s2.0-S0140673620322339?scrollTo=%23hl0000424 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32233-9/fulltext do statins work in old...

18 Marras 20209min

154. SGLT2, Mindfulness, Pill on a String

154. SGLT2, Mindfulness, Pill on a String

https://www.acpjournals.org/doi/10.7326/M20-2470 Pharmacologic Approaches to Glycemic Treatment of Type 2 Diabetes: Synopsis of the 2020 American Diabetes Association's Standards of Medical Care in Di...

15 Marras 202024min

153. Weight Loss, Fever, Back Pain, EKGs

153. Weight Loss, Fever, Back Pain, EKGs

https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2771093 meta-analysis of 78 original studies, looking to find the accuracy of ECG interpretation. In this analysis they looked at stud...

8 Marras 202020min

152. Atypical Drug Trials, SGLT2, Frozen Shoulder, Physical Therapy

152. Atypical Drug Trials, SGLT2, Frozen Shoulder, Physical Therapy

https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2771670 trials are not real life. We know that. Realistically if your drug just barely hits 0.05 in a clinical trial then in the imper...

1 Marras 202022min

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