Episode 296: 295. What is the Best Blood Pressure In the Nursing Home?

Episode 296: 295. What is the Best Blood Pressure In the Nursing Home?

In a retrospective cohort study of Veterans Affairs (VA) nursing home residents during 2006 to 2019, researchers identified 13,000 residents who initiated a first or additional antihypertensive medication and 52,000 propensity score–matched controls (mean age, 78). The primary outcome was a composite of pelvic fracture, surgically treated hip fracture, and fractures of the humerus, radius, and ulna that required intervention within 30 days of starting antihypertensive medication.

Initiating medication also was associated with elevated risks for falls that required emergency room visits or hospitalizations (aHR, 1.8) and elevated risks of syncope (aHR, 1.7).

Fracture risks were elevated, compared with controls, in initiators with a systolic blood pressure ≥140 mm Hg (aHR, 3.1), diastolic blood pressure ≥80 mm Hg (aHR, 4.4), and no recent antihypertensive medication use (aHR, 4.8).

Jaksot(386)

Episode 327: 326. Should We Prescribe Inhaled Insulin? INHALE-3 TRIAL

Episode 327: 326. Should We Prescribe Inhaled Insulin? INHALE-3 TRIAL

INHALE-3, a randomized trial, 123patients with type 1 dm that compared the efficacy of an inhaled insulin regimen (Afrezza) plus degludec insulin (Tresiba®) against usual care over 17 weeks The study'...

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Episode 326: 325. The Mysterious NNT

Episode 326: 325. The Mysterious NNT

What is a quick and easy way to calculate the NNT

30 Heinä 20247min

Episode 325: 324. METHODS MONDAY

Episode 325: 324. METHODS MONDAY

What is the different between Absolute and Relative risk reduction

29 Heinä 20248min

Episode 324: 323. Is Calcium Bad For You? Calcium Supplementation? Eating Calcium?

Episode 324: 323. Is Calcium Bad For You? Calcium Supplementation? Eating Calcium?

https://heart.bmj.com/content/108/12/964https://www.ahajournals.org/doi/10.1161/JAHA.116.003815We have a study that says leads to increase all cause death with calcium supplementsWe have a study that ...

26 Heinä 202413min

Episode 323: 322. Follow-up to Adolescence after Early Peanut Introduction for Allergy Prevention

Episode 323: 322. Follow-up to Adolescence after Early Peanut Introduction for Allergy Prevention

https://evidence.nejm.org/doi/full/10.1056/EVIDoa2300311Peanut consumption, starting in infancy and continuing to age 5 years, provided lasting tolerance to peanut into adolescence irrespective of sub...

24 Heinä 20245min

Episode 322: 321. Long-Term Outcomes in Patients with Low Risk Prostate Cancer

Episode 322: 321. Long-Term Outcomes in Patients with Low Risk Prostate Cancer

https://jamanetwork.com/journals/jama/article-abstract/2819352Conclusions and Relevance  In this study, 10 years after diagnosis, 49% of men remained free of progression or treatment, less than 2% dev...

23 Heinä 20246min

Episode 321: 320. What is the Association of Blood Lipids, Lipoproteins, and Apolipoproteins With Risk of Coronary Heart Disease

Episode 321: 320. What is the Association of Blood Lipids, Lipoproteins, and Apolipoproteins With Risk of Coronary Heart Disease

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11179824/This study did something smart in that they broke it down by white black Chinese and then also had 36 lab test they were looking at and they then ...

19 Heinä 20248min

Episode 320: 319. President Biden has COVID, Should the First Lady Take Paxlovid?

Episode 320: 319. President Biden has COVID, Should the First Lady Take Paxlovid?

https://www.nejm.org/doi/full/10.1056/NEJMoa2309002In this placebo-controlled trial, postexposure prophylaxis with nirmatrelvir–ritonavir for 5 or 10 days did not significantly reduce the risk of symp...

18 Heinä 20248min

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