Episode 310: 309. Hospital-Associated Venous Thromboembolism Prophylaxis Use by Risk Assessment

Episode 310: 309. Hospital-Associated Venous Thromboembolism Prophylaxis Use by Risk Assessment

https://shmpublications.onlinelibrary.wiley.com/doi/abs/10.1002/jhm.13350


Xu J et al. Hospital-associated venous thromboembolism prophylaxis use by risk assessment at a large integrated health care network in Northern California. J Hosp Med 2024 Jun; 19:449.



Authors took 850,000 adult nonsurgical, non–intensive care unit (ICU) hospitalizations at 21 Kaiser Permanente hospitals in northern California, and did a retrospective study of inpatient pharmacologic VTE prophylaxis, investigators compared risk assessment by admitting physicians with risk assessment according to electronic health record (EHR)-

The EHR used the Padua prediction score which basically ask yes or no questions like does the pt have active cancer, previous vte, reduce mobility, elderly age, heart or resp failure. All questions that could need a human to fill out but also with could AI or HER should be answered without humans doing anything.



In 82% of 850,000 adult nonsurgical, non–intensive care unit (ICU) hospitalizations, the EHR categorized patients as low risk (i.e., not meeting indications for pharmacologic VTE prophylaxis); however, 42% of such patients (≈300,000 patients) received pharmacologic VTE prophylaxis. Among the 18% of hospitalizations where Padua score assessments indicated high risk (i.e., met indications for pharmacologic VTE prophylaxis), only one third received pharmacologic VTE prophylaxis.

There was years of making sure people give VTE but maybe we have went to far but the only way to solve this problem is give doctors fewer patient and more time or make it incorporated into the HER automatically. Make it idiot proof.

Hospitals should begin to incorporate better validated tools within EHRs to guide clinical decision-making for inpatient VTE prophylaxis. But even without such tools, clinicians should be vigilant in applying pharmacologic VTE prophylaxis in high-risk patients and minimizing its use in patients at low risk.

Jaksot(385)

Episode 391: 402. Functional disability after clinically significant extracranial bleeding: a secondary analysis of ASPREE

Episode 391: 402. Functional disability after clinically significant extracranial bleeding: a secondary analysis of ASPREE

https://www.jthjournal.org/article/S1538-7836(25)00109-6/fulltextAntithrombotic agents, like aspirin and anticoagulants, are essential for treating many cardiovascular conditions. However, a common si...

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Episode 390: 401. Add-On Treatment With Zilebesiran for Inadequately Controlled Hypertension

Episode 390: 401. Add-On Treatment With Zilebesiran for Inadequately Controlled Hypertension

https://jamanetwork.com/journals/jama/article-abstract/2834632SummaryThe article examines the effectiveness and safety of zilebesiran, an RNA interference therapeutic agent, when used in combination w...

4 Kesä 20258min

Episode 389: 400. CRP, Lipoprotein A, LDL for cardiac risk assessment

Episode 389: 400. CRP, Lipoprotein A, LDL for cardiac risk assessment

https://www.nejm.org/doi/full/10.1056/NEJMoa2405182?query=recirc_Semantic  Key Takeaways Extended Predictive Value of Biomarkers: High-sensitivity C-reactive protein (CRP), LDL cholesterol, and lipop...

29 Touko 20259min

Episode 388: 399. Use of albumin-adjusted calcium measurements in clinical practice

Episode 388: 399. Use of albumin-adjusted calcium measurements in clinical practice

Desgagnés N et al. Use of albumin-adjusted calcium measurements in clinical practice. JAMA Netw Open 2025 Jan 21; 8:e2455251. (https://doi.org/10.1001/jamanetworkopen.2024.55251)Overall, total calcium...

27 Touko 20257min

Episode 387: 398. Which is Better, Tirzepatide or Semaglutide?

Episode 387: 398. Which is Better, Tirzepatide or Semaglutide?

https://www.nejm.org/doi/10.1056/NEJMoa2416394At 72 weeks, the mean percentage decrease in weight was significantly greater with tirzepatide than with semaglutide (20% vs. 14%). Gastrointestinal side ...

21 Touko 20258min

Episode 386: 397. What is the new drug for smoking cessation?

Episode 386: 397. What is the new drug for smoking cessation?

https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2832701In this multisite trial, 800 adults who smoked 10 or more cigarettes daily (mean duration of smoking, ≈35 years) were randomize...

9 Touko 20255min

Episode 385: 396. Vitamin D and Kids (CME)

Episode 385: 396. Vitamin D and Kids (CME)

What does the evidence and the guidelines say about the use and testing of Vitamin D in kids

7 Touko 20258min

Episode 384: 395. How accurate is the BMI?

Episode 384: 395. How accurate is the BMI?

Aryee EK et al. Prevalence of obesity with and without confirmation of excess adiposity among US adults. JAMA 2025 Apr 17; [e-pub]. (https://doi.org/10.1001/jama.2025.2704)The rate of obesity was 39.7...

6 Touko 20255min

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