Science’s leading role in the restoration of Notre Dame and the surprising biology behind how our body develops its tough skin

Science’s leading role in the restoration of Notre Dame and the surprising biology behind how our body develops its tough skin

On this week’s show, freelance writer Christa Lesté-Lasserre talks with host Sarah Crespi about the scientists working on the restoration of Notre Dame, from testing the changing weight of wet limestone, to how to remove lead contamination from four-story stained glass windows. As the emergency phase of work winds down, scientists are also starting to use the lull in tourist activity to investigate the mysteries of the cathedral’s construction. Also this week, Felipe Quiroz, an assistant professor in the biomedical engineering department at the Georgia Institute of Technology and Emory University, talks with Sarah about his paper on the cellular mechanism of liquid-liquid phase separation in the formation of the tough outer layer of the skin. Liquid-liquid phase separation is when two liquids “demix,” or separate, like oil and water. In cells, this process created membraneless organelles that are just now starting to be understood. In this work, Quiroz and colleagues create a sensor for phase separation in the cell that works in living tissue, and show how phase separation is tied to the formation of the outer layers of skin in mice. Read the related Insight. This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF). [Image: r. nial bradshaw/Flickr; Music: Jeffrey Cook] Authors: Sarah Crespi; Christa Lesté-Lasserre Learn more about your ad choices. Visit megaphone.fm/adchoices

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Tales from an Italian crypt, and the science behind ‘dad bods’

Tales from an Italian crypt, and the science behind ‘dad bods’

First up on the podcast, Contributing Correspondent Andrew Curry talks with host Sarah Crespi about his visit to 17th century crypts under an old hospital in Italy. Researchers are examining tooth pla...

1 Touko 202532min

A caterpillar that haunts spiderwebs, solving the last riddles of a famed friar, and a new book series

A caterpillar that haunts spiderwebs, solving the last riddles of a famed friar, and a new book series

First up on the podcast, bringing Gregor Mendel’s peas into the 21st century. Back in the 19th century Mendel, a friar and naturalist, tracked traits in peas such as flower color and shape over many g...

24 Huhti 202545min

Linking cat domestication to ancient cult sacrifices, and watching aurorae wander

Linking cat domestication to ancient cult sacrifices, and watching aurorae wander

First up on the podcast, Online News Editor David Grimm joins host Sarah Crespi to talk about how an Egyptian cult that killed cats may have also tamed them.   Next on the show, we hear about when the...

17 Huhti 202526min

The metabolic consequences of skipping sleep, and cuts and layoffs slam NIH

The metabolic consequences of skipping sleep, and cuts and layoffs slam NIH

First up on the podcast, ScienceInsider Editor Jocelyn Kaiser joins host Sarah Crespi to discuss big changes in science funding and government jobs this month, including an order to cut billions in co...

10 Huhti 202528min

Talking about engineering the climate, and treating severe nausea and vomiting during pregnancy

Talking about engineering the climate, and treating severe nausea and vomiting during pregnancy

Geoengineering experiments face an uphill battle, and a way to combat the pregnancy complication hyperemesis gravidarum First up on the podcast, climate engineers face tough conversations with the pu...

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Studying urban wildfires, and the challenges of creating tiny AI robots

Studying urban wildfires, and the challenges of creating tiny AI robots

First up this week, urban wildfires raged in Los Angeles in January. Contributing Correspondent Warren Cornwall discusses how researchers have come together to study how pollution from buildings at su...

27 Maalis 202532min

Why seals don’t drown, and tracking bird poop as it enters the sea

Why seals don’t drown, and tracking bird poop as it enters the sea

First up this week, Newsletter Editor Christie Wilcox joins host Sarah Crespi to discuss stories from the sea, including why scientists mounted cameras on seabirds, backward and upside-down; newly dis...

20 Maalis 202538min

Why sign language could be crucial for kids with cochlear implants, studying the illusion of pain, and recent political developments at NIH

Why sign language could be crucial for kids with cochlear implants, studying the illusion of pain, and recent political developments at NIH

First up this week, science policy editor Jocelyn Kaiser joins host Sarah Crespi to discuss the latest news about the National Institutes of Health—from reconfiguring review panels to canceled grants ...

13 Maalis 202542min

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