First Assist: The Historical Context of Advanced Kidney Cancer, with Eric A. Singer, MD

First Assist: The Historical Context of Advanced Kidney Cancer, with Eric A. Singer, MD

In this episode of First Assist: GU Oncology Unpacked, host Taylor Goodstein, MD, speaks with Eric A. Singer, MD, MA, MS, FACS, FASCO, The Dave Longaberger Endowed Chair in Urology, professor of urology and bioethics, chief of the urologic oncology, and director of the Urologic Oncology Fellowship Program at The Ohio State University in Columbus about how historical milestones in genitourinary oncology; specifically, kidney cancer, have shaped current practice.

Singer traces the evolution of kidney cancer management from the era of radical surgery to today’s precision approaches, highlighting how improved imaging, minimally invasive techniques, and molecular insights have transformed treatment. He underscores the shift from one-size-fits-all surgery toward tailored strategies that balance oncologic control with preservation of renal function and quality of life.

The discussion also explores the arc of immunotherapy in urologic cancers—from early cytokine-based regimens to the immune checkpoint inhibitors now embedded in standard care. Singer reflects on how clinical trial design, patient selection, and biomarker research are driving more individualized therapy choices.

Throughout the conversation, Goodstein emphasizes the value of understanding the past to better interpret the present and anticipate the future. The two also address how a deeper appreciation for the history of GU oncology can help trainees navigate today’s rapidly expanding knowledge base without losing sight of core principles.

Looking ahead, Singer points to ongoing challenges, including optimizing multidisciplinary collaboration, improving trial access for diverse patient populations, and integrating novel therapies in ways that are both evidence-based and patient-centered. His take-home message: progress in GU oncology is built on decades of incremental advances, and the next wave of breakthroughs will require the same blend of innovation, rigorous science, and thoughtful application.

Chapters
1:30 Where does the story of kidney cancer treatment begin?
6:54 The strengths and limitations of IL-2
17:40 Comparing mTOR inhibitors and TKIs
25:38 Cytoreductive nephrectomy
36:00 First-line regimens
45:09 Upcoming trials to watch

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The Expert APProach: Advancing APP Leadership and Expertise in Urology, With Susanne Quallich, PhD, ANP-BC, NP-C

The Expert APProach: Advancing APP Leadership and Expertise in Urology, With Susanne Quallich, PhD, ANP-BC, NP-C

Susanne Quallich, PhD, ANP-BC, NP-C, discusses APP leadership, specialization, professional growth, and expanding the role of APPs in urology.

20 Elo 28min

Pearls & Perspectives: Patient Expectations, Physician Autonomy, and Life Beyond Surgery, With Andrew T. Cohen, MD, FACS

Pearls & Perspectives: Patient Expectations, Physician Autonomy, and Life Beyond Surgery, With Andrew T. Cohen, MD, FACS

In this episode of Pearls & Perspectives, host Amy Pearlman, MD, and plastic surgeon Andrew T. Cohen, MD, FACS, discuss managing patient expectations and the importance of cultivating balance outside ...

12 Elo 39min

The UroOnc Minute: Navigating BCG Maintenance Therapy in NMIBC, With Mark D. Tyson, II, MD, MPH

The UroOnc Minute: Navigating BCG Maintenance Therapy in NMIBC, With Mark D. Tyson, II, MD, MPH

In this episode of The UroOnc Minute, Mark D. Tyson, II, MD, MPH, joins host Adam Weiner, MD, to discuss the importance of BCG maintenance therapy in NMIBC and share strategies for navigating treatmen...

12 Elo 13min

Pearls & Perspectives: Wearable Technology and the Future of Sexual Health, With Elliot Justin, MD

Pearls & Perspectives: Wearable Technology and the Future of Sexual Health, With Elliot Justin, MD

Host Amy Pearlman, MD, and guests Larry Lipshultz, MD, and Elliot Justin, MD, explore the potential of wearable technology to advance the diagnosis, monitoring, and optimization of sexual health for b...

12 Elo 15min

Pearls & Perspectives: From Prostate Cancer Diagnosis to Patient Advocacy, with Gabe Canales

Pearls & Perspectives: From Prostate Cancer Diagnosis to Patient Advocacy, with Gabe Canales

In this episode of Pearls & Perspectives, host Amy Pearlman, MD, is joined by male reproductive specialist Larry Lipshultz, MD, and patient advocate Gabe Canales for a candid conversation about prosta...

12 Elo 15min

The UroOnc Minute: Optimizing Patient Follow-Up in Urologic Oncology, With Jason Hafron, MD

The UroOnc Minute: Optimizing Patient Follow-Up in Urologic Oncology, With Jason Hafron, MD

In this episode of The UroOnc Minute, host Adam Weiner, MD, is joined by Jason Hafron, MD, to discuss how data-driven pathways and patient follow-up systems can improve quality and outcomes in urologi...

24 Heinä 12min

Pearls & Perspectives: Understanding the Long-Term Health Effects of Military Exposures, With Shane Kronstedt, MD

Pearls & Perspectives: Understanding the Long-Term Health Effects of Military Exposures, With Shane Kronstedt, MD

Host Amy Pearlman, MD, and Larry Lipshultz, MD, speak with Shane Kronstedt, MD, about research on the long-term urologic effects of military exposures and how these findings may help improve care for ...

22 Heinä 5min

First Assist: Early Cystectomy in Non–Muscle Invasive Bladder Cancer, with Matvey Tsivian, MD

First Assist: Early Cystectomy in Non–Muscle Invasive Bladder Cancer, with Matvey Tsivian, MD

In this episode of First Assist: GU Oncology Unpacked, host Taylor Goodstein, MD, is joined by Matvey Tsivian, MD, to discuss how patient selection, staging, and quality-of-life considerations influen...

15 Heinä 49min

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