The Truth About Treatment-Resistant Depression: Part Two (TMS and Psychedelics)

Treatment-resistant depression can feel like the end of the road, but there are more options than most people realize. Beyond traditional antidepressants, a range of innovative treatments exist, including:

• Electroconvulsive therapy (ECT)
• Repetitive Transcranial magnetic stimulation (rTMS)
• Vagus nerve stimulation
• Rapid-acting compounds like ketamine, esketamine, and psilocybin

These treatments are offering new hope for patients who haven’t found relief in the current standard of care.

In this second part of our three-part series, Dr. Georgia Ede and Dr. Bret Scher dive deep into the science, effectiveness, and practical considerations of these approaches. You’ll learn how these treatments work, the evidence behind them, and what to expect in terms of accessibility, cost, and side effects.

From the rapid results of ketamine (sometimes within a single day) to the growing public awareness of rTMS, this discussion explores both cutting-edge and underutilized options, plus the barriers that still keep many from accessing them.

Watch now to discover why “treatment-resistant” doesn’t mean “hopeless,” and be on the lookout for Part 3, where we’ll explore powerful (and accessible) lifestyle and metabolic interventions that can complement or even replace medical treatments.

Expert Featured:

Dr. Georgia Ede

• Website: https://www.diagnosisdiet.com/
• Book: https://www.diagnosisdiet.com/change-your-diet-change-your-mind
• YouTube: ‪@GeorgiaEdeMD‬
• X: https://x.com/GeorgiaEdeMD
• IG: https://www.instagram.com/georgiaedemd/

Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.

Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/

About us:

Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.

Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.