Can modelling tell us what factors influence CAUTI in long and short-term catheters?

Can modelling tell us what factors influence CAUTI in long and short-term catheters?

In this episode, Brett, Phil and Martin discuss a recent paper from Freya Bull and colleagues, who undertook a modelling exercise to determine what factors determine the colonisation process for long and short-term urinary catheters. It turns out that different factors are in play here and that strategies for CAUTI prevention miht be different for each.

You can read the paper here:

Bull F, Tavaddod S, Bommer N, Perry M, Brackley CA, Allen RJ. Different factors control long-term versus short-term outcomes for bacterial colonisation of a urinary catheter. Nat Commun 2025;16(1):3940. https://doi.org/10.1038/s41467-025-59161-y.

Brett's group's previous work on short-term catheters is here:

Fasugba O, Cheng AC, Gregory V, Graves N, Koerner J, Collignon P, et al. Chlorhexidine for meatal cleaning in reducing catheter-associated urinary tract infections: a multicentre stepped-wedge randomised controlled trial. Lancet Infect Dis 2019;19(6):611-9. https://doi.org/10.1016/S1473-3099(18)30736-9.

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